2. Infection

Infection

Infection

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Infection is a pathophysiological process that involves the invasion and colonization of a living organism (host) by disease-causing infectious agents, the reaction of host tissues to these agents and the toxins they produce, and the transmission of infectious agents to other hosts. Common infectious agents include viruses, viroids, prions, bacteria, nematodes, arthropods, and other macroparasites such as tapeworms. Hosts can fight infections using their immune system. Mammals often engage both innate and adaptive immune systems to eliminate infectious agents or inhibit their growth and transmission. When infection occurs, anti-infective drugs can suppress the infection. Several broad types of anti-infective drugs exist, depending on the type of organism targeted; they include antibacterial (antibiotic), antiviral, antifungal and antiparasitic agents.

Cat. No. Product Name CAS No. Purity Chemical Structure
  • HY-152614
    Antimalarial agent 19 2897630-89-4 98%
    Antimalarial agent 19 (compound 6e) is an antimalarial active agent. Antimalarial agent 19 has antimalarial activity for the blood stage of P. falciparum K1 and P. berghei with EC50 values of 0.3 µM, 15.3 µM, respectively. Antimalarial agent 19 has good aqueous solubility, intestinal permeability and microsomal stability compared to gamhepathiopine.
    Antimalarial agent 19
  • HY-152668
    Urease-IN-4 98%
    Urease-IN-4 is an effective inhibitor of urease with an IC50 value of 1.64 µM. Urease-IN-4 has low cytotoxicity and shows inhibitory activity on P. vulgaris with an IC50 value of 15.27 µg/mL.
    Urease-IN-4
  • HY-152669
    Urease-IN-5 98%
    Urease-IN-5 is an inhibitor of urease with an IC50 value of 1.473 µM. Urease-IN-5 has low cytotoxicity and inhibitory activity on P. vulgaris with an IC50 value of 17.78 µg/mL.
    Urease-IN-5
  • HY-152726
    TLR7 agonist 9 2389988-38-7 98%
    TLR7 agonist 9 (compound 10) is an aonist of TLR7. TLR7 agonist 9 can be used for research of cancer and infectious disease. TLR7 agonist 9 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
    TLR7 agonist 9
  • HY-15278R
    Utidelone (Standard) 189453-10-9
    Utidelone (Standard) (Epothilone D (Standard)) is the analytical standard ofUtidelone. This product is intended for research and analytical applications. Utidelone is a potent microtubule stabilizer.
    Utidelone (Standard)
  • HY-152896
    Ys-II 897386-27-5 98%
    Ys-II (Compound 1) is a spirostanol glycoside that can be isolated from the stem of Yucca elephantipe. Ys-II has antifungal activity against the growth of Candida albicans and Cryptococcus neoformans (IC50: 5 and 6 μg/mL respectively).
    Ys-II
  • HY-152909
    Nystatin A2 65086-32-0 98%
    Nystatin A2 is an active component of antifungal agent, Nystatin (HY-17409). Nystatin is an orally active polyene antifungal antibiotic effective against yeast and mycoplasma.
    Nystatin A2
  • HY-152957
    STING agonist-24 2408722-91-6 98%
    STING agonist-24 (CF504) is a non-nucleotide small-molecule STING agonist. STING agonist-23 activates STING, increases phosphorylation of STING, TBK1 and IRF3. STING agonist-23 promotes the levels of IFN-β, IL-6, CXCL-10, TNF-α, ISG-15, and CCL-5 in tumor cells. STING agonist-23 exhibits activity against SARS-CoV series strains.
    STING agonist-24
  • HY-152958
    STING agonist-25 2408723-10-2 98%
    STING agonist-25 (CF505) is a non-nucleotide small-molecule STING agonist. STING agonist-23 activates STING, increases phosphorylation of STING, TBK1 and IRF3. STING agonist-23 promotes the levels of IFN-β, IL-6, CXCL-10, TNF-α, ISG-15, and CCL-5 in tumor cells. STING agonist-23 exhibits activity against SARS-CoV series strains.
    STING agonist-25
  • HY-152960
    STING agonist-27 2868261-45-2 98%
    STING agonist-27 (CF509) is a non-nucleotide small-molecule STING agonist. STING agonist-23 activates STING, exhibits activity against SARS-CoV series strains.
    STING agonist-27
  • HY-152961
    STING agonist-28 2868261-50-9 98%
    STING agonist-28 (CF510) is a non-nucleotide small-molecule STING agonist. STING agonist-23 activates STING, increases phosphorylation of STING, TBK1 and IRF3. STING agonist-23 promotes the levels of IFN-β, IL-6, CXCL-10, TNF-α, ISG-15, and CCL-5 in tumor cells. STING agonist-23 exhibits activity against SARS-CoV series strains.
    STING agonist-28
  • HY-152962
    STING agonist-29 2868261-51-0 98%
    STING agonist-29 (CF511) is a non-nucleotide small-molecule STING agonist. STING agonist-23 activates STING, exhibits activity against SARS-CoV series strains.
    STING agonist-29
  • HY-153005
    (2RS)-FPMPA 135295-27-1 98%
    (2RS)-FPMPA can be used for synthesis of antiretroviral agents against HIV-1 and HIV-2.
    (2RS)-FPMPA
  • HY-153009
    MMV676584 750621-19-3 99.82%
    MMV676584 has anti-tuberculosis avtivity. MMV676584 is a novel agent candidate for eumycetoma.
    MMV676584
  • HY-15303S
    Pritelivir-d4-1 98%
    Pritelivir-d4-1 (AIC316-d4-1) is deuterium labeled Pritelivir. Pritelivir (AIC316), an inhibitor of the viral helicase-primase complex, exhibits antiviral activity in vitro and in animal models of herpes simplex virus (HSV) infection. Pritelivir is active against herpes simplex virus types 1 and 2 (HSV-1 and HSV-2) with the IC50 of 0.02 μM against HSV1-2.
    Pritelivir-d4-1
  • HY-153062
    6-Chloro-7-deazapurine-2F-β-D-arabinofuranose 169516-60-3 98%
    6-Chloro-7-deazapurine-2F-β-D-arabinofuranose is a nucleoside derivative. 6-Chloro-7-deazapurine-2F-β-D-arabinofuranose can be used for synthesis of antiviral agent against hepatitis C virus infection.
    6-Chloro-7-deazapurine-2F-β-D-arabinofuranose
  • HY-153073
    TLR7 agonist 8 2380231-81-0 98%
    TLR7 agonist 8 is a TLR7 agonist with an EC50 of 0.12 nM for TLR7 and an EC50 of 0.76 nM for IL-6 induction. TLR7 agonist 8 can be used for research on diseases such as fibrosis, inflammatory diseases, cancer, or pathogen infections.
    TLR7 agonist 8
  • HY-153238
    AN15368 2152662-92-3 98%
    AN15368 is an orally active trypanocidal agent and a prodrug of AN14667. AN15368 selectively targets CPSF3-mediated mRNA maturation in intracellular amastigotes of Trypanosoma cruzi, reducing the mRNA levels of the parasite. As a prodrug, AN15368 can be cleaved into its active carboxylate form by CBP of Trypanosoma cruzi. AN15368 completely clears long-term naturally acquired Trypanosoma cruzi infections in non-human primates. AN15368 can be used in the research of Chagas disease.
    AN15368
  • HY-153247
    GSK3839919A 2081127-77-5 98%
    GSK3839919A is a potent and allosteric HIV-1integrase inhibitor.
    GSK3839919A
  • HY-153271
    Antibacterial agent 321 67389-41-7 98%
    Antifungal agent 147 (compound 2) is a lipophilic antibacterial agent with dark toxicity. Antifungal agent 147 shows a phototoxic effect on S. aureus and E. coli. Antifungal agent 147 can penetrate the bacterial cell membrane and disturb its structure, leading to dark toxicity. Antifungal agent 147 can be used for bacteria infection research.
    Antibacterial agent 321
Cat. No. Product Name / Synonyms Application Reactivity