TLR7 agonist 8
TLR7 agonist 8 is a TLR7 agonist with an EC50 of 0.12 nM for TLR7 and an EC50 of 0.76 nM for IL-6 induction. TLR7 agonist 8 can be used for research on diseases such as fibrosis, inflammatory diseases, cancer, or pathogen infections.
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- CAS No.: 2380231-81-0
- Formule: C29H32N6O3
- Masse moléculaire:512.60
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Stockage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Activité biologique
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Chemical Information
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- Pureté et documentation
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Help & FAQs
Activité biologique
Description
IC50 & Target
[1]|
TLR7 0.12 nM (EC50) |
IL-6 0.76 nM (EC50) |
In Vitro
TLR7 agonist 8 (Compound IIb-34) potently activates TLR7 in HEK Blue cells with an EC50 of 0.12 nM[1].
TLR7 agonist 8 potently induces IL-6 with an EC50 of 0.76 nM[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 2380231-81-0
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Masse moléculaire 512.60
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Formule C29H32N6O3
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SMILES
OC(N1C2=NC(OCC/C=C\CC3=CC(C1)=CC=C3C4=CC=C(C=C4)CNC5CCOCC5)=N6)=NC2=C6N
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Livraison
Room temperature in continental US; may vary elsewhere.
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Stockage
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureté et documentation
Références
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
TLR7 agonist 8 Related Classifications
HY-153073 Related Classifications
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