MMV676584
Based on 1 Customer Validation
MMV676584 has anti-tuberculosis avtivity. MMV676584 is a novel agent candidate for eumycetoma.
For research use only. We do not sell to patients.
- Purity: 99.82%
- CAS No.: 750621-19-3
- Formula: C12H8ClFN2OS2
- Molecular Weight:314.79
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Storage:
4°C, protect from light
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
Chemical Information
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CAS No. 750621-19-3
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Appearance Solid
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Molecular Weight 314.79
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Formula C12H8ClFN2OS2
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Color White to off-white
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SMILES
O=C(C1=C(Cl)C2=C(C=C(C=C2)F)S1)NC3=NCCS3
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
4°C, protect from light
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
Solvent & Solubility
DMSO : 125 mg/mL (397.09 mM; ultrasonic and warming and heat to 60°C; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (270 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Portuguese - PT (252 KB)
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Handling Instructions (2659 KB)
References
[1]. Wilson Lim, et al. Addressing the most neglected diseases through an open research model: The discovery of fenarimols as novel drug candidates for eumycetoma. PLoS Negl Trop Dis. 2018 Apr 26;12(4):e0006437. [Content Brief]
[2]. Clinton G L Veale, et al. Unpacking the Pathogen Box-An Open Source Tool for Fighting Neglected Tropical Disease. ChemMedChem. 2019 Feb 19;14(4):386-453. [Content Brief]
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 3.1767 mL | 15.8836 mL | 31.7672 mL | 79.4180 mL |
| 5 mM | 0.6353 mL | 3.1767 mL | 6.3534 mL | 15.8836 mL | |
| 10 mM | 0.3177 mL | 1.5884 mL | 3.1767 mL | 7.9418 mL | |
| 15 mM | 0.2118 mL | 1.0589 mL | 2.1178 mL | 5.2945 mL | |
| 20 mM | 0.1588 mL | 0.7942 mL | 1.5884 mL | 3.9709 mL | |
| 25 mM | 0.1271 mL | 0.6353 mL | 1.2707 mL | 3.1767 mL | |
| 30 mM | 0.1059 mL | 0.5295 mL | 1.0589 mL | 2.6473 mL | |
| 40 mM | 0.0794 mL | 0.3971 mL | 0.7942 mL | 1.9855 mL | |
| 50 mM | 0.0635 mL | 0.3177 mL | 0.6353 mL | 1.5884 mL | |
| 60 mM | 0.0529 mL | 0.2647 mL | 0.5295 mL | 1.3236 mL | |
| 80 mM | 0.0397 mL | 0.1985 mL | 0.3971 mL | 0.9927 mL | |
| 100 mM | 0.0318 mL | 0.1588 mL | 0.3177 mL | 0.7942 mL |
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