2. Infection

Infection

Infection

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Infection is a pathophysiological process that involves the invasion and colonization of a living organism (host) by disease-causing infectious agents, the reaction of host tissues to these agents and the toxins they produce, and the transmission of infectious agents to other hosts. Common infectious agents include viruses, viroids, prions, bacteria, nematodes, arthropods, and other macroparasites such as tapeworms. Hosts can fight infections using their immune system. Mammals often engage both innate and adaptive immune systems to eliminate infectious agents or inhibit their growth and transmission. When infection occurs, anti-infective drugs can suppress the infection. Several broad types of anti-infective drugs exist, depending on the type of organism targeted; they include antibacterial (antibiotic), antiviral, antifungal and antiparasitic agents.

Cat. No. Product Name CAS No. Purity Chemical Structure
  • HY-N1054
    Zamanic acid 260393-05-3 98%
    Zamanic acid is a potent inhibitor of glutathione reductase. Zamanic acid inhibits the growth of Mycobacterium tuberculosis in culture and has also been shown to have anti-inflammatory activity.
    Zamanic acid
  • HY-N1117
    Tristin 139101-67-0 99.26%
    Tristin is a PTP1B inhibitor (IC50=21.2 μM) with antioxidant and antifungal activities. Tristin inhibits lipid peroxidation and NO production in LPS-stimulated macrophages, and also exhibits activity against a variety of phytopathogenic fungi. Tristin is also able to inhibit cancer cell proliferation. Tristin can be used in the research of diseases associated with phytopathogenic fungal infection, leukemia, type 2 diabetes and inflammatory responses.
    Tristin
  • HY-N1151
    Thunberginol C 147517-06-4 98%
    Thunberginol C is an orally active, selective, and non-competitive inhibitor of AChE and BChE, with IC50 values of 41.96 and 42.36 μM, respectively. Thunberginol C exerts cytoprotective, pro-collagen type I restorative, MMP-1 inhibitory, hyaluronic acid restorative, anti-photoaging effects in skin cells. Thunberginol C exerts neuroprotective, anxiolytic, TNF-α inhibitory, neuroinflammation inhibitory, and oxidative stress inhibitory effects. Thunberginol C can be used for the research of Alzheimer’s disease, UVB-induced skin photoaging, allergic reactions, oral bacterial infections, and stress-induced anxiety.
    Thunberginol C
  • HY-N1180
    Tanshinlactone 105351-70-0 98%
    Tanshinlactone is a compound found in Salvia miltiorrhiza with anti-coronavirus (CoV) and anti-tumor activities. Tanshinlactone induces methuocytic cell death (methuosis) by activating the NRF2 pathway, and selectively kills ER+, HER2+/EGFR+ breast cancer cells. Tanshinlactone is applicable to research related to breast cancer and coronavirus infections.
    Tanshinlactone
  • HY-N1190
    DL-Syringaresinol 1177-14-6
    DL-Syringaresinol ((±)-Syringaresinol), a lignin, inhibits UVA-induced upregulation of MMP-1 by suppressing MAPK/AP-1 signaling in human HaCaT keratinocytes and dermal fibroblasts (HDFs). DL-Syringaresinol has antiphotoaging properties against UVA-induced skin aging. DL-Syringaresinol exhibits weak antimycobacterial activity against Mycobacterium tuberculosis H37Rv.
    DL-Syringaresinol
  • HY-N1300
    Shizukanolide F 120061-96-3 98%
    Shizukanolide F is a dimeric sesquiterpene, which is derivated from Chloranthus japonicus Sieb. Shizukanolide F exhibits potent antifungal activities against various plant pathogenic fungi and anti-metastasis breast cancer.
    Shizukanolide F
  • HY-N1320
    Sambutoxin 160047-56-3 98%
    Sambutoxin is a mycotoxin. Sambutoxin can be isolated from wheat culture of Fusarium sambucinum.
    Sambutoxin
  • HY-N1520
    Rediocide A 280565-85-7 98%
    Rediocide A is a highly modified daphnane with potent insecticidal activity. Rediocide A can be isolated from Trigonostemon reidioides.
    Rediocide A
  • HY-N1672
    5,7,2′,6′-Tetrahydroxyflavanone 80604-16-6 98%
    5,7,2 ',6 '-Tetrahydroxyflavanone is an extract isolated from Scutellaria baicalensis. 5,7,2 ',6 '-Tetrahydroxyflavanone has significant antibacterial activity against gram-positive bacteria. 5,7,2 ',6 '-Tetrahydroxyflavanone can be used to study the treatment of inflammatory diseases .
    5,7,2′,6′-Tetrahydroxyflavanone
  • HY-N1751
    (Rac)-Phytene-1,2-diol 438536-34-6 98%
    7,11,15-Trimethyl-3-methylidenehexadecane-1,2-diol is a terpenoid that can be isolated from Eupatorium fortunei. 7,11,15-Trimethyl-3-methylidenehexadecane-1,2-diol is used in dropsy, chill, and fever research.
    (Rac)-Phytene-1,2-diol
  • HY-N1779
    (E)-3,4-Dimethoxycinnamyl alcohol 40918-90-9 98%
    (E)-3,4-Dimethoxycinnamyl alcohol is an antimutagenic. (E)-3,4-Dimethoxycinnamyl alcohol has antimutagenic activity against furylfuramide, Trp-P-1, and activated Trp-P-1.
    (E)-3,4-Dimethoxycinnamyl alcohol
  • HY-N2225
    Isorhamnetin-3-O-sophoroside-7-O-rhamnoside 41328-75-0 98%
    Isorhamnetin-3-O-sophoroside-7-O-rhamnoside, the major flavonol glycoside, is isolated from sea buckthorn (Hippopha rhamnoides). Isorhamnetin-3-O-sophoroside-7-O-rhamnoside has the algicidal activity against the growth of the harmful microalgae.
    Isorhamnetin-3-O-sophoroside-7-O-rhamnoside
  • HY-N2351
    Paeonoside 20309-70-0 99.59%
    Paeonoside is a bioactive compound identified in P. suffruticosa that promotes wound healing and migration in osteoblast differentiation. Paeonoside has also been reported to have some antidiabetic activity and may prevent sepsis-induced lethality.
    Paeonoside
  • HY-N2789
    (9Z)-9,17-Octadecadiene-12,14-diyne-1,11,16-triol 211238-60-7 98%
    (9Z)-9,17-Octadecadiene-12,14-diyne-1,11,16-triol is a nature product that could be isolated from the ethyl acetate extract of Cassonia barteri (Araliaceae) leaves. (9Z)-9,17-Octadecadiene-12,14-diyne-1,11,16-triol has antibacterial activity against Bacillus subtilis and Pseudomonas fluorescens, antifungal activity against Cladosporium cucumerinum, moiluscicidal activity against Biomphalaria glabrata. (9Z)-9,17-Octadecadiene-12,14-diyne-1,11,16-triol is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
    (9Z)-9,17-Octadecadiene-12,14-diyne-1,11,16-triol
  • HY-N2876
    Anisofolin A 83529-71-9 98%
    Anisofolin A is a flavonoid that can be isolated from Anisomeles indica. Anisofolin A has antimalarial activity (IC50: 4.39 μM), and antimycobacterium activity (IC50: 4.50 μM) against M. tuberculosis H37Ra.
    Anisofolin A
  • HY-N2899
    Arteannuin M 207446-90-0 98%
    Arteannuin M can be isolated from Artemisia annua, and can be used for anti-malarial research.
    Arteannuin M
  • HY-N2903
    Artoheterophyllin B 1174017-37-8 98%
    Artoheterophyllin B can be isolated from A. heterophyllus. Artoheterophyllin B shows antiplasmodial activity (IC50: 13.7 μM against FcB1 strain). Artoheterophyllin B can be used for anti-malarial research.
    Artoheterophyllin B
  • HY-N2927
    Costic acid 3650-43-9 98%
    Costic acid (β-Costic acid) is a natural product, that can be isolated from Dittrichia viscosa. Costic acid exhibits potent in vivo acaricidal activity against the parasite. Costic acid is not toxic for human umbilical vein endothelial cells (HUVEC) at concentrations of up to 230 μM. Costic acid can be used for the research of varroosis in honey bee colonies.
    Costic acid
  • HY-N2932
    β-Yohimbine 549-84-8 98%
    β-Yohimbine (Amsonin) is an indole alkaloid that can be isolated from Aspidosperma ulei Markgr. β-Yohimbine shows antiplasmodial activity against the Chloroquine (HY-17589A)-resistant Fc M29-Cameroon strain (IC50: > 1 μg/mL).
    β-Yohimbine
  • HY-N2982
    Caesalmin E 204185-91-1 98%
    Caesalmin E is a natural cassane furanoditerpene with anti-Para3 (Parainfluenza virus type 3) virus activities.
    Caesalmin E
Cat. No. Product Name / Synonyms Application Reactivity