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Cat. No.: HY-N1190

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DL-Syringaresinol

(Synonyms: (±)-Syringaresinol)

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Based on 1 Customer Validation

DL-Syringaresinol ((±)-Syringaresinol), a lignin, inhibits UVA-induced upregulation of MMP-1 by suppressing MAPK/AP-1 signaling in human HaCaT keratinocytes and dermal fibroblasts (HDFs). DL-Syringaresinol has antiphotoaging properties against UVA-induced skin aging. DL-Syringaresinol exhibits weak antimycobacterial activity against Mycobacterium tuberculosis H37Rv.

For research use only. We do not sell to patients.

Purity: 96%
CAS No.: 1177-14-6
Formula: C₂₂H₂₆O₈
Molecular Weight:418.44

Storage:

4°C, sealed storage, away from moisture and light

* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)

DL-Syringaresinol Chemical Structure

CAS No.: 1177-14-6

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Top Publications Citing

Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity

Description

All p38 MAPK Isoforms :

All AP-1 Isoforms :

Chemical Information

CAS No. 1177-14-6
Appearance Solid
Molecular Weight 418.44
Formula C₂₂H₂₆O₈
Color Light brown to yellow
SMILES

OC1=C(OC)C=C([C@H]2OC[C@@]3([H])[C@]2([H])CO[C@@H]3C4=CC(OC)=C(O)C(OC)=C4)C=C1OC
Synonyms

(±)-Syringaresinol
Structure Classification
- Phenylpropanoids
- Lignans
Initial Source
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

4°C, sealed storage, away from moisture and light

* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (272 KB)
SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Su-Yen Chang, et al. Antimycobacterial butanolides from the root of Lindera akoensis. Chem Biodivers. 2008 Dec;5(12):2690-8. [Content Brief]

[2]. Jung Hwan Oh, et al. Syringaresinol Inhibits UVA-Induced MMP-1 Expression by Suppression of MAPK/AP-1 Signaling in HaCaT Keratinocytes and Human Dermal Fibroblasts. Int J Mol Sci. 2020 Jun 1;21(11):3981. [Content Brief]

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Keywords

100 mg

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Biological Activity
- Description
Chemical Information
Purity & Documentation
References

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DL-Syringaresinol

All p38 MAPK Isoforms

All AP-1 Isoforms