2. Infection

Infection

Infection

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Infection is a pathophysiological process that involves the invasion and colonization of a living organism (host) by disease-causing infectious agents, the reaction of host tissues to these agents and the toxins they produce, and the transmission of infectious agents to other hosts. Common infectious agents include viruses, viroids, prions, bacteria, nematodes, arthropods, and other macroparasites such as tapeworms. Hosts can fight infections using their immune system. Mammals often engage both innate and adaptive immune systems to eliminate infectious agents or inhibit their growth and transmission. When infection occurs, anti-infective drugs can suppress the infection. Several broad types of anti-infective drugs exist, depending on the type of organism targeted; they include antibacterial (antibiotic), antiviral, antifungal and antiparasitic agents.

Cat. No. Product Name CAS No. Purity Chemical Structure
  • HY-N2984
    Calanolide E 142566-61-8 98%
    Calanolide E is a natural coumarin with weakly inhibitory towards the Bacilli strains with MIC values ranging from 0.25-0.50 mg/mL.
    Calanolide E
  • HY-N3060
    (S)-5,7-Diacetoxyflavanone 111441-88-4 98%
    (S)-5,7-Diacetoxyflavanone is a flavanone with antimicrobial activity.
    (S)-5,7-Diacetoxyflavanone
  • HY-N3088
    Phaseollidin hydrate 76122-57-1 98%
    Phaseollidin hydrate is the hydrate form of the antimicrobial phytoalexin Phaseollidin, which has lower antifungal activity than the original Phaseollidin.
    Phaseollidin hydrate
  • HY-N3094
    Periglaucine A 1025023-04-4 98%
    Periglaucine A, a hasubanane-type alkaloid, can be isolated from Pericampylus glaucus. Periglaucine A can inhibits HBV surface antigen (HBsAg) secretion in Hep G2.2.15 cells. Periglaucine A also shows anti-HIV-1 activity in C8166 cells (EC50: 204 μM).
    Periglaucine A
  • HY-N3160
    Erythrinasinate B 101959-37-9 98%
    Octacosyl (E)-ferulate (Erythrinasinate B) (Compound 1) is an antiplasmodial compound. Octacosyl (E)-ferulate can be isolated from Erythrina.
    Erythrinasinate B
  • HY-N3185
    N-Methylcalycinine 86537-66-8 98%
    N-Methylcalycinine is a nature product with AChE inhibitory activity. N-Methylcalycinine can be isolated from the roots of Stephania epigaea. N-Methylcalycinine can be used for the research of asthma, cancer, dysentery, fever, hyperglycemia, intestinal complaints, inflammation, sleep disturbances, tuberculosis and so on.
    N-Methylcalycinine
  • HY-N3212
    Naringenin trimethyl ether 38302-15-7 98.76%
    Naringenin trimethyl ether is a constituent of twigs and leaves of Aglaia duperreana. Naringenin trimethyl exhibits significant molluscicidal activity, with a LC50 of 3.9 μg/ mL for P. canaliculata.
    Naringenin trimethyl ether
  • HY-N3445
    Jaceidin triacetate 14397-69-4 98%
    Jaceidin triacetate(compound 54) is a natural compound isolated formmarulabark.Jaceidin triacetatecan inhibitSARS-CoV-2 Mpro, with theIC50of 11.9μM.Jaceidin triacetateinhibits the replication of Sars-Cov-2 Viral in Vero-E6 cells.
    Jaceidin triacetate
  • HY-N3549
    Catalpin 1390-72-3 98%
    Catalpin is an iridoid that can be isoalted from Catalpae Fructus.Catalpin shows mutagenic activity towards Salmonella typhimurium strain TA100.
    Catalpin
  • HY-N3569
    Cerbinal 65597-42-4 98%
    Cerbinal is a natural compound isolated from Gardenia jasminoides Ellis. Cerbinal has antifungal activity.
    Cerbinal
  • HY-N3609
    Coclauril 127350-68-9 98%
    Coclauril is an inhibitor of HBV. Coclauril inhibits HBV replication in the human hepatoblastoma cell line with an EC50 of 7.6 μg/mL.
    Coclauril
  • HY-N3640
    Crenatine 26585-14-8 98%
    Crenatine is an antibacterial agent. Crenatine is more effective against Gram-positive than Gram-negative bacteria.
    Crenatine
  • HY-N3700
    Decarine 54354-62-0 98%
    Decarine (Rutaceline) is a benzophenanthridine alkaloid found in Zanthoxylum species. Decarinewith shows anti-inflammatory, antimycobacterial, and anti-HIV activity. Decarine inhibits NO, TNF-α, IL-1β, IL-6, and IL-8 production in inflammatory cell models. Decarine inhibits growth of Mycobacterium tuberculosis strains, reduces intracellular Mycobacterium tuberculosis survival, and shows low cytotoxicity toward human macrophages. Decarine inhibits HIV replication in acutely infected lymphocytes. Decarine can be used for the researches of inflammation, tuberculosis, and HIV infection.
    Decarine
  • HY-N3702
    Dehydroabietinol 3772-55-2 98.90%
    Dehydroabietinol is a SYK inhibitor with an IC50 of 46.4 μM. Dehydroabietinol inhibits the growth of Trypanosoma cruzi epimastigotes, Leishmania braziliensis promastigotes and Leishmania infantum promastigotes. Dehydroabietinol indirectly inhibits the growth of Plasmodium falciparum, alters the erythrocyte membrane, and induces spherostomatocyte transformation and endovesicle formation. Dehydroabietinol can be used in studies related to immune-mediated diseases, Chagas disease, leishmaniasis and malaria.
    Dehydroabietinol
  • HY-N3989
    Haplopine 5876-17-5 99.49%
    Haplopine is a substance with anti-inflammatory, antioxidant and photoactivated antibacterial activities. It also acts as an inhibitor of UGT1A7 and a photoactivated restriction endonuclease inhibitor. Haplopine inhibits the mRNA/protein expression of IL-6, TSLP, GM-CSF, G-CSF, IL-4, IL-13 and COX-2, while upregulating the mRNA/protein expression of SOD, CAT and HO-1. Haplopine inhibits the glucuronidation reaction catalyzed by UGT1A7 through competitive hydrophobic binding. Haplopine exerts photoactivated restriction endonuclease inhibitory effects by binding to DNA. Haplopine exhibits photoactivated activity against methicillin-resistant Staphylococcus aureus. Haplopine alleviates symptoms of atopic dermatitis. Haplopine can be used in research related to atopic dermatitis and methicillin-resistant Staphylococcus aureus infections.
    Haplopine
  • HY-N5167
    Argimicin A 321846-46-2 98%
    Argimicin A is an antibiotic that can be isolated from Sphingomonas sp.. Argimicin A exhibits algicidal activity against toxic cyanobacteria, inhibits M. viridis and M. aeruginosa with IC50s of 12 ng/mL and 100 ng/mL.
    Argimicin A
  • HY-N5168
    Argimicin B 663910-32-5 98%
    Argimicin B is an antibiotic that can be isolated from Sphingomonas sp.. Argimicin B exhibits algicidal activity against a variety of toxic cyanobacteria with MIC of low micromolar levels.
    Argimicin B
  • HY-N5169
    Argimicin C 663910-33-6 98%
    Argimicin C is an antibiotic that can be isolated from Sphingomonas sp.. Argimicin C exhibits algicidal activity against a variety of toxic cyanobacteria with MIC of low micromolar levels.
    Argimicin C
  • HY-N5173
    Aibellin 151036-29-2 98%
    Aibellin, a peptide antibiotic, is a useful and potent modifier of rumen fermentation.
    Aibellin
  • HY-N5174
    Azetomycin II 59481-55-9 98%
    Azetomycin II (Azet-II) has the effect of anti-Gram positive bacteria.
    Azetomycin II
Cat. No. Product Name / Synonyms Application Reactivity