1. Inflammation/Immunology

Inflammation/Immunology (炎症/免疫)

The diseases caused by disorders of the immune system fall into two broad categories: immunodeficiency and autoimmunity. Immunotherapy is also often used in the immunosuppressed (such as HIV patients) and people suffering from other immune deficiencies or autoimmune diseases. This includes regulating factors such as IL-2, IL-10, IFN-α. Infection with HIV is characterized not only by development of profound immunodeficiency but also by sustained inflammation and immune activation. Chronic inflammation as a critical driver of immune dysfunction, premature appearance of aging-related diseases, and immune deficiency.

製品番号 製品名 CAS 番号 純度 構造式
  • HY-P990820
    Anti-Mouse TIM-4 Antibody (RMT4-53)
    Anti-Mouse TIM-4 Antibody (RMT4-53) is a rat-derived IgG2b κ type antibody inhibitor, targeting to mouse TIM-4. Anti-Mouse TIM-4 Antibody (RMT4-53) can block T cell immunoglobulin and mucin domain 4 (TIM-4). Anti-Mouse TIM-4 Antibody (RMT4-53) can inhibit the engulfment of apoptotic cells and T cell proliferation. Anti-Mouse TIM-4 Antibody (RMT4-53) can be used for the researches of cancer, immunology and metabolic disease, such as MC38 tumor and graft.
    Anti-Mouse TIM-4 Antibody (RMT4-53)
  • HY-P990835
    Anti-LFA-1α/CD11a Antibody (TS-1/22.1.1.13)
    Anti-LFA-1α/CD11a Antibody (TS-1/22.1.1.13) is a kind of mouse IgG1 chimeric antibody inhibitor, targeting to human LFA-1α/CD11a. Anti-LFA-1α/CD11a Antibody (TS-1/22.1.1.13) reacts with human LFA-1α (lymphocyte function-associated antigen 1 alpha) also known as integrin alpha L chain and CD11a. Anti-LFA-1α/CD11a Antibody (TS-1/22.1.1.13) can be used for the researches of immunology and infection, such as human immunodeficiency virus (HIV).
    Anti-LFA-1α/CD11a Antibody (TS-1/22.1.1.13)
  • HY-P990898
    Amlenetug 2850367-41-6 99.85%
    HY-P990898 is an SNCA-targeting IgG1κ type human antibody, the recommed isotype control is Human IgG1 kappa, Isotype Control (HY-P99001).
    Amlenetug
  • HY-P990913
    Dalmitamig 2765077-69-6
    HY-P990913 is an EGFR/CD28-targeting IgG4κ type human antibody, the recommed isotype control is Human IgG4 (S228P) kappa, Isotype Control (HY-P99003).
    Dalmitamig
  • HY-P990918
    Emiltatug 2855971-15-0 99%
    HY-P990918 is an VTCN1-targeting IgG1κ type human antibody, the recommed isotype control is Human IgG1 kappa, Isotype Control (HY-P99001).
    Emiltatug
  • HY-P991114
    Adezkibart 2921564-55-6
    Adezkibart is a human monoclonal antibody immunosuppressant targeting the human FMS-like tyrosine kinase 3 ligand (FLT3LG). Adezkibart is found in the Chinese hamster ovary cell line CHO-K1, which binds to FLT3LG to block the relevant signaling pathway, inhibits the immune response, and exerts immunosuppressive activity. Adezkibart is promising for research of immune-related diseases.
    Adezkibart
  • HY-P991209
    Nebratamig 2694723-68-5
    Nebratamig (GNC-035) is an anti-ROR1/anti-CD3/anti-PD-L1/anti-4-1BB tetra-specific antibody with potential immunostimulatory and antineoplastic activities.
    Nebratamig
  • HY-P991907
    Anti-CD80 Antibody (TKMF5)
    Anti-CD80 Antibody (TKMF5) is an antibody against human CD80. Recommend Isotype Controls:?Human IgG1 kappa, Isotype Control (HY-P99001).
    Anti-CD80 Antibody (TKMF5)
  • HY-W010625
    Lithium 2-hydroxypropanoate 867-55-0
    Lithium 2-hydroxypropanoate is a lithium salt. Lithium 2-hydroxypropanoate has immunomodulatory activity (slightly enhancing PHA (HY-N7038)-induced lymphocyte proliferation). Lithium 2-hydroxypropanoate can be used in antioxidant activity assays. Lithium 2-hydroxypropanoate can be used in the research of mental diseases.
    Lithium 2-hydroxypropanoate
  • HY-W011398
    Linoleate sodium 822-17-3 99.88%
    Linoleate sodium is an orally active IL8 regulator via the JNK and NF-κB pathway. Linoleate sodium can change the composition of fatty acids and the production of metabolites in cells. Linoleate sodium has anti-inflammatory, immune-regulating, and tumor cell growth-affecting activities.
    Linoleate sodium
  • HY-W032848
    Tinoridine 24237-54-5
    Tinoridine (Y-3642) is an orally active non-steroidal anti-inflammatory agent with potent antiperoxidative ability and radical scavenger activity. Tinoridine acts function by inhibiting COX enzyme, involves in hepatotoxicity inhibition. .
    Tinoridine
  • HY-W040471
    3′,5′-Dimethoxyacetophenone

    3′,5′-Dimethoxyacetophenone

    39151-19-4 99.91%
    3′,5′-Dimethoxyacetophenone is a ketone compound with antioxidant activity. 3′,5′-Dimethoxyacetophenone is also a building block in chemical synthesis.
    3′,5′-Dimethoxyacetophenone
  • HY-W091541
    4-Hydroxy-1H-indole-3-carbaldehyde 81779-27-3 99.67%
    4-Hydroxy-1H-indole-3-carbaldehyde (4-Hydroxyindole-3-carboxaldehyde) is a plant metabolite. 4-Hydroxy-1H-indole-3-carbaldehyde can be isolated from Capparis spinosa L. 4-Hydroxy-1H-indole-3-carbaldehyde can be used in the synthesis of fluorescent probe. 4-Hydroxy-1H-indole-3-carbaldehyde can be used in the study of inflammation-related diseases.
    4-Hydroxy-1H-indole-3-carbaldehyde
  • HY-W097994
    DHMB 4055-69-0 98.67%
    DHMB (2,3-Dihydroxy-4-methoxybenzaldehyde) is a small organic molecule with anti-fungal and anti-inflammatory activity. DHMB has protective effect on intestinal epithelial cells.
    DHMB
  • HY-W440915
    DSPE-PEG2000-FITC 1000788-53-3 99.76%
    DSPE-PEG2000-FITC is a PEG lipid conjugated with fluorescein. FITC is a green dye with a peak absorption at 494 nm and a maximum emission at 520 nm, which is used for staining biological samples or nanoparticles. DSPE-PEG2000-FITC spontaneously forms lipid bilayers or micelles in water and can be used to prepare liposomes for delivering substances such as mRNA vaccines.
    DSPE-PEG2000-FITC
  • HY-W442049
    Hydroxypinacolone retinoate 893412-73-2 99.33%
    Hydroxypinacolone retinoate (HPR) is a retinol derivative, which binds directly with retinoic acid receptors (RARs). Hydroxypinacolone retinoate, when used in combination with Retinyl propionate, can be used in anti-skin aging research.
    Hydroxypinacolone retinoate
  • HY-W709553
    Glyceryl Triformate 32765-69-8
    Glyceryl Triformate (Triglyceride) is the major form of storage and transport of fatty acids within cells and in the plasma. Glyceryl Triformate forms lipoproteins with cholesterol ester, and participates in the blood circulation. Glyceryl Triformate can lead to hypertriglyceridemia (HTG), which increases the risk of atherosclerotic cardiovascular disease (ASCVD) and pancreatitis.
    Glyceryl Triformate
  • HY-W011927R
    4,4'-Sulfonyldiphenol (Standard) 80-09-1 99.33%
    4,4'-Sulfonyldiphenol (Bisphenol S; Bis(4-hydroxyphenyl) sulfone) (Standard) is the analytical standard of 4,4'-Sulfonyldiphenol (HY-W011927). This product is intended for research and analytical applications. 4,4'-Sulfonyldiphenol, a substitute for Bisphenol A (HY-18260), is widely used in industrial and consumer products. 4,4'-Sulfonyldiphenol is an estrogen receptor (ER) agonist and can competitively bind to thyroid hormone receptors (TR) with IC50 values for TRα and TRβ are 2650 μM and 2294 μM respectively, thereby affecting breast development and reducing the expression of androgen receptor (AR) in fetal testes. 4,4'-Sulfonyldiphenol promotes the progression of glioblastoma by upregulating the EZH2 mediated PI3K/AKT/mTOR pathway. Under chronic exposure, 4,4'-Sulfonyldiphenol can cause significant lipid deposition and dyslipidemia in the mouse liver by upregulating JunB and Atf3, and has a role in causing obesity at low doses. 4,4'-Sulfonyldiphenol induces intestinal inflammation by altering the intestinal microbiome. 4,4'-Sulfonyldiphenol accelerates the progression of atherosclerosis in zebrafish embryo larvae.
    4,4'-Sulfonyldiphenol (Standard)
  • HY-101041
    (E)-AG 556 133550-41-1 99.91%
    (E)-AG 556 is a highly selective EGFR inhibitor and also blocks LPS-induced TNF-α production.
    (E)-AG 556
  • HY-115532
    BCL6-IN-7 2097518-46-0 99.79%
    BCL6-IN-7 is a potent BCL6−corepressor interaction inhibitor.
    BCL6-IN-7
製品番号 製品名 / Synonyms Application Reactivity