1. Inflammation/Immunology

Inflammation/Immunology

The diseases caused by disorders of the immune system fall into two broad categories: immunodeficiency and autoimmunity. Immunotherapy is also often used in the immunosuppressed (such as HIV patients) and people suffering from other immune deficiencies or autoimmune diseases. This includes regulating factors such as IL-2, IL-10, IFN-α. Infection with HIV is characterized not only by development of profound immunodeficiency but also by sustained inflammation and immune activation. Chronic inflammation as a critical driver of immune dysfunction, premature appearance of aging-related diseases, and immune deficiency.

Cat. No. Product Name CAS No. Purity Chemical Structure
  • HY-B1137
    Ramifenazone 3615-24-5 98.99%
    Ramifenazone (Isopropylaminoantipyrine) is a pyrazole derivative and acts as a non-steroidal anti-inflammatory agent (NSAID). Ramifenazone has analgesic, antipyretic, anti-inflammatory and antimicrobial activities.
    Ramifenazone
  • HY-B1166
    Cefamandole nafate 42540-40-9
    Cefamandole nafate (Cefamandole formate sodium) is a second-generation broad-spectrum cephalosporin antibiotic.
    Cefamandole nafate
  • HY-B2205
    Magnesium silicate 1343-88-0
    Magnesium silicate (Activated magnesium silicate) is an orally active compound composed of magnesium oxide (MgO) and silicon dioxide (SiO2). Magnesium silicate can be used in the preparation of food additives, antacids and anti-ulcer agents. Magnesium silicate is also a piezoelectric biomaterial, deodorant, decolorizing agent and antifungal agent.
    Magnesium silicate
  • HY-113152
    Hypogeic acid (50mg/ml in ethanol) 2416-19-5 ≥98.0%
    Hypogeic acid is a fatty acid and endogenous metabolite, with a concentration of 50 mg/mL in ethanol. The plasma level of Hypogeic acid is negatively correlated with the prevalence of interstitial lung disease in idiopathic inflammatory myopathy. Hypogeic acid can be used in studies related to idiopathic inflammatory myopathy.
    Hypogeic acid (50mg/ml in ethanol)
  • HY-122756
    N-Palmitoyl-l-leucine 14379-42-1 99.98%
    N-Palmitoyl-l-leucine (GK144) is a secreted phospholipases A2 inhibitor. N-Palmitoyl-l-leucine can be used for inflammatory diseases.
    N-Palmitoyl-l-leucine
  • HY-131686
    Ganglioside GT1b (bovine) ammonium 59247-13-1 98.0%
    Ganglioside GT1b (bovine) ammonium is a member of the ganglioside family. Ganglioside GT1b (bovine) ammonium acts as a protective signal against nerve injury-induced spinal synapse elimination. Ganglioside GT1b (bovine) ammonium induces HA synthesis and the phosphorylation of Akt/mTOR in orbital fibroblasts. Ganglioside GT1b (bovine) ammonium enhances porcine oocyte maturation and induce activation of EGFR and ERK1/2 signaling. Ganglioside GT1b (bovine) ammonium is a putative host cell receptor for the Merkel cell polyomavirus. Ganglioside GT1b (bovine) ammonium can be used for the researches of cancer, infection, immunology, endocrinology and neurological disease, such as Thyroid eye disease.
    Ganglioside GT1b (bovine) ammonium
  • HY-134560
    N-(3-Oxodecanoyl)-L-homoserine lactone 147795-40-2 99.62%
    N-(3-Oxodecanoyl)-L-homoserine lactone (3-Oxo-C10-HSL) is a bacterial quorum sensing signal autoinducer molecule.
    N-(3-Oxodecanoyl)-L-homoserine lactone
  • HY-15036A
    Diclofenac diethylamine 78213-16-8 99.95%
    Diclofenac diethylamine is a potent and nonselective anti-inflammatory agent, acts as a COX inhibitor, with IC50s of 4 and 1.3 nM for human COX-1 and COX-2 in CHO cells, and 5.1 and 0.84 μM for ovine COX-1 and COX-2, respectively. Diclofenac diethylamine induces apoptosis of neural stem cells (NSCs) via the activation of the caspase cascade.
    Diclofenac diethylamine
  • HY-158285
    25-OH Vitamin D3/BSA
    25-OH Vitamin D3/BSA is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
    25-OH Vitamin D3/BSA
  • HY-40354S
    Tofacitinib-13C3 2256762-71-5 99.77%
    Tofacitinib-13C3 is the 13C-labeled Tofacitinib. Tofacitinib is an orally available JAK3/2/1 inhibitor with IC50s of 1, 20, and 112 nM, respectively.
    Tofacitinib-13C3
  • HY-B1193R
    Terfenadine (Standard) 50679-08-8 99.91%
    Terfenadine (Standard) is the analytical standard of Terfenadine. This product is intended for research and analytical applications. Terfenadine ((±)-Terfenadine) is a potent open-channel blocker of hERG with an IC50 of 204 nM. Terfenadine, an H1 histamine receptor antagonist, acts as a potent apoptosis inducer in melanoma cells through modulation of Ca2+ homeostasis. Terfenadine induces ROS-dependent apoptosis, simultaneously activates Caspase-4, -2, -9.
    Terfenadine (Standard)
  • HY-N0337R
    Eugenol (Standard) 97-53-0 99.87%
    Eugenol (Standard) is the analytical standard of Eugenol. This product is intended for research and analytical applications. Eugenol is an essential oil found in cloves with antibacterial, anthelmintic and antioxidant activity. Eugenol is shown to inhibit lipid peroxidation.
    Eugenol (Standard)
  • HY-N0709R
    Coumarin (Standard) 91-64-5 99.96%
    Coumarin (Standard) is the analytical standard of Coumarin. This product is intended for research and analytical applications. Coumarin is a potent and orally active anti-inflammatory agent. Coumarin shows an antinociceptive effect. Coumarin shows antibacterial, antifungal and anticancer activity.
    Coumarin (Standard)
  • HY-N0808R
    Camphor (Standard) 76-22-2 99.86%
    Camphor (Standard) is the analytical standard of Camphor. This product is intended for research and analytical applications. Camphor ((±)-Camphor) is a topical anti-infective and anti-pruritic and internally as a stimulant and carminative. However, Camphor is poisonous when ingested. Antiviral, antitussive, and anticancer activities. Camphor is a TRPV3 agonist.
    Camphor (Standard)
  • HY-N10620
    Melitidin 1162664-58-5 98.63%
    Melitidin is a flavanone glycoside, that can be isolated from Citrus grandis 'Tomentosa'. Melitidin shows a good antitussive effect on cough induced by citric acid in Guinea pig.
    Melitidin
  • HY-N12777
    Coixenolide 29066-43-1 99.93%
    Coixenolide can be isolated from coix seeds, and exhibits anti-inflammatory, anti-tumor and pain-reducing activities. Coixenolide stimulates the lung, heart, striated and smooth muscles at low doses, while inhibits at high doses. Coixenolide dilates pulmonary veins and improves pulmonary blood circulation. Coixenolide can also be used as nutraceuticals and functional foods. Coixenolide enhances the prodcutionof mycelia biomass and polysaccharides when added to the media of submerged culture of G. lucidum. Coixenolide affects the synthesis level of phosphoglucose isomerase and α-phosphoglucomutase.
    Coixenolide
  • HY-N1981R
    Triolein (Standard) 122-32-7 99.88%
    Triolein (Standard) is the analytical standard of Triolein. This product is intended for research and analytical applications. Triolein is a symmetric triacylglycerol that reduces upregulation of MMP-1 and has strong antioxidant and anti-inflammatory activities.
    Triolein (Standard)
  • HY-N2041R
    Myristic acid (Standard) 544-63-8 99.98%
    Myristic acid (Standard) is the analytical standard of Myristic acid. This product is intended for research and analytical applications. Myristic acid is an orally active saturated 14-carbon fatty acid found in most animal and plant fats, especially milk fat coconut oil, palm oil and nutmeg oil. Myristic acid exerts anti-inflammatory activity through the NF-κB pathway. Myristic acid has antibacterial, anti-inflammatory and analgesic properties.
    Myristic acid (Standard)
  • HY-N6911A
    18α-Glycyrrhizic acid 83896-44-0 99.90%
    18α-Glycyrrhizic acid is a derivate of Glycyrrhizic acid. 18α-Glycyrrhizic acid has weak antihepatotoxic anti-inflammatory activities.
    18α-Glycyrrhizic acid
  • HY-P99135
    Anti-Mouse MHC Class I (H-2Kb) Antibody (Y-3) 99.16%
    Anti-Mouse MHC Class I (H-2Kb) Antibody (Y-3) is a mouse-derived IgG2b antibody inhibitor, targeting to mouse MHC Class I (H-2Kb). Anti-Mouse MHC Class I (H-2Kb) Antibody (Y-3) reacts with the mouse H-2Kb, H-2Kk, H-2Kq, H-2Kr, H-2ks MHC class I alloantigens and not H-2Kd. Anti-Mouse MHC Class I (H-2Kb) Antibody (Y-3) can block MHC Class I. Anti-Mouse MHC Class I (H-2Kb) Antibody (Y-3) can be used for immunology research.
    Anti-Mouse MHC Class I (H-2Kb) Antibody (Y-3)
Cat. No. Product Name / Synonyms Application Reactivity