Ramifenazone
Based on 1 Customer Validation
Ramifenazone (Isopropylaminoantipyrine) is a pyrazolone non-steroidal anti-inflammatory agent (NSAID) and a potent COX-2 inhibitor. Ramifenazone exhibits analgesic, antipyretic, anti-inflammatory, and antibacterial activities. Ramifenazone can be used for research on inflammation.
For research use only. We do not sell to patients.
- Purity : 98.99%
- CAS No.: 3615-24-5
- Formula: C14H19N3O
- Molecular Weight:245.32
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Storage:
4°C, protect from light
* The compound is unstable in solutions, freshly prepared is recommended.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
Description
IC50 & Target
[3]|
COX-2 |
In Vitro
Ramifenazone can be detected and quantified in bovine muscle by an LC-MS/MS multi-residue method, with a decision limit of 23 μg/kg and a detection capability of 26 μg/kg, demonstrating adequate apparent recovery, repeatability, and within-laboratory reproducibility[4].
Ramifenazone is detected and quantified in bovine milk by an LC-MS/MS multi-residue method, with a decision limit of 25 μg/kg and a detection capability of 31 μg/kg, and RMZ in milk exhibits the highest measurement uncertainty (47%), indicating reduced method ruggedness for this compound[4].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 3615-24-5
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Appearance Solid
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Molecular Weight 245.32
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Formula C14H19N3O
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Color White to off-white
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SMILES
O=C1N(C2=CC=CC=C2)N(C)C(C)=C1NC(C)C
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Synonyms
Isopropylaminoantipyrine
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
4°C, protect from light
* The compound is unstable in solutions, freshly prepared is recommended.
Purity & Documentation
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Data Sheet (282 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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Handling Instructions (2659 KB)
References
[2]. Surendra Kumar R, et al. Anti-inflammatory and antimicrobial activities of novel pyrazole analogues. Saudi journal of biological sciences. 2016 Sep;23(5):614-20. [Content Brief]
[3]. Nehra B, et al. Recent advancements in the development of bioactive pyrazoline derivatives. European journal of medicinal chemistry. 2020 Nov 01;205:112666. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Ramifenazone Related Classifications
HY-B1137 Related Classifications
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