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Cat. No.: HY-B1137S

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Ramifenazone-d₇

Name: Ramifenazone-d7
Brand: MedChemExpress
SKU: HY-B1137S
Availability: PreOrder

(Synonyms: Isopropylaminoantipyrine-d₇)

Ramifenazone-d₇ (Isopropylaminoantipyrine-d₇) is the deuterated-labeled Ramifenazone (HY-B1137). Ramifenazone (Isopropylaminoantipyrine) is a pyrazolone non-steroidal anti-inflammatory agent (NSAID) and a potent COX-2 inhibitor. Ramifenazone exhibits analgesic, antipyretic, anti-inflammatory, and antibacterial activities. Ramifenazone can be used for research on inflammation.

For research use only. We do not sell to patients.

CAS No.: 1330180-51-2
Formula: C₁₄H₁₂D₇N₃O
Molecular Weight:252.36

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (282 KB)

Ramifenazone-d₇ Chemical Structure

CAS No.: 1330180-51-2

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Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

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Description

IC₅₀ & Target

^[3]

COX-2

All COX Isoforms :

Application

1. This compound can be used as a tracer
2. This compound can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.

Chemical Information

CAS No. 1330180-51-2
Unlabeled CAS 3615-24-5
Molecular Weight 252.36
Formula C₁₄H₁₂D₇N₃O
SMILES

O=C1N(N(C)C(C)=C1NC(C([2H])([2H])[2H])(C([2H])([2H])[2H])[2H])C2=CC=CC=C2
Synonyms

Isopropylaminoantipyrine-d₇
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (282 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Nath R, et al. Pyrazole Derivatives as Selective COX-2 Inhibitors: An Updated Review. Antiinflamm Antiallergy Agents Med Chem. 2026;25(2):91-106.

[2]. Surendra Kumar R, et al. Anti-inflammatory and antimicrobial activities of novel pyrazole analogues. Saudi journal of biological sciences. 2016 Sep;23(5):614-20. [Content Brief]

[3]. Nehra B, et al. Recent advancements in the development of bioactive pyrazoline derivatives. European journal of medicinal chemistry. 2020 Nov 01;205:112666. [Content Brief]

[4]. van Pamel E, et al. A multiresidue liquid chromatographic/tandem mass spectrometric method for the detection and quantitation of 15 nonsteroidal anti-inflammatory drugs (NSAIDs) in bovine meat and milk. Analytical and bioanalytical chemistry. 2015 Jun;407(15):4485-94.

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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Ramifenazone-d7

All COX Isoforms

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