1330180-51-2
Chemical Structure
Ramifenazone-d7
Synonym(s): Isopropylaminoantipyrine-d7
- CAS No.: 1330180-51-2
- Formula:C14H12D7N3O
- Molecular Weight:252.36
IUPAC Name: 1,5-dimethyl-2-phenyl-4-((propan-2-yl-d7)amino)-1,2-dihydro-3H-pyrazol-3-one
InChIKey: XOZLRRYPUKAKMU-SVMCCORHSA-N
SMILES: O=C1N(N(C)C(C)=C1NC(C([2H])([2H])[2H])(C([2H])([2H])[2H])[2H])C2=CC=CC=C2
Biological Activity: Ramifenazone-d7 (Isopropylaminoantipyrine-d7) is the deuterated-labeled Ramifenazone (HY-B1137). Ramifenazone (Isopropylaminoantipyrine) is a pyrazolone non-steroidal anti-inflammatory agent (NSAID) and a potent COX-2 inhibitor. Ramifenazone exhibits analgesic, antipyretic, anti-inflammatory, and antibacterial activities. Ramifenazone can be used for research on inflammation[1][2][3][4].
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Ramifenazone-d7 | Ramifenazone-d7 (Isopropylaminoantipyrine-d7) is the deuterated-labeled Ramifenazone (HY-B1137). Ramifenazone (Isopropylaminoantipyrine) is a pyrazolone non-steroidal anti-inflammatory agent (NSAID) and a potent COX-2 inhibitor. Ramifenazone exhibits analgesic, antipyretic, anti-inflammatory, and antibacterial activities. Ramifenazone can be used for research on inflammation. | |||||||||||||||||||||
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Ramifenazone (Standard) | ≥98% | Ramifenazone (Isopropylaminoantipyrine) Standard is the analytical standard of Ramifenazone (HY-B1137). This product is intended for research and analytical applications. Ramifenazone (Isopropylaminoantipyrine) is a pyrazolone non-steroidal anti-inflammatory agent (NSAID) and a potent COX-2 inhibitor. Ramifenazone exhibits analgesic, antipyretic, anti-inflammatory, and antibacterial activities. Ramifenazone can be used for research on inflammation. | ||||||||||||||||||||
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Ramifenazone | 98.99% | Ramifenazone (Isopropylaminoantipyrine) is a pyrazolone non-steroidal anti-inflammatory agent (NSAID) and a potent COX-2 inhibitor. Ramifenazone exhibits analgesic, antipyretic, anti-inflammatory, and antibacterial activities. Ramifenazone can be used for research on inflammation. | ||||||||||||||||||||
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References
- [1]. Nath R, et al. Pyrazole Derivatives as Selective COX-2 Inhibitors: An Updated Review. Antiinflamm Antiallergy Agents Med Chem. 2026;25(2):91-106.
- [2]. Surendra Kumar R, et al. Anti-inflammatory and antimicrobial activities of novel pyrazole analogues. Saudi journal of biological sciences. 2016 Sep;23(5):614-20. [Content Brief]
- [3]. Nehra B, et al. Recent advancements in the development of bioactive pyrazoline derivatives. European journal of medicinal chemistry. 2020 Nov 01;205:112666. [Content Brief]
- [4]. van Pamel E, et al. A multiresidue liquid chromatographic/tandem mass spectrometric method for the detection and quantitation of 15 nonsteroidal anti-inflammatory drugs (NSAIDs) in bovine meat and milk. Analytical and bioanalytical chemistry. 2015 Jun;407(15):4485-94.
