2. Inflammation/Immunology

Inflammation/Immunology

Inflammation/Immunology

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The diseases caused by disorders of the immune system fall into two broad categories: immunodeficiency and autoimmunity. Immunotherapy is also often used in the immunosuppressed (such as HIV patients) and people suffering from other immune deficiencies or autoimmune diseases. This includes regulating factors such as IL-2, IL-10, IFN-α. Infection with HIV is characterized not only by development of profound immunodeficiency but also by sustained inflammation and immune activation. Chronic inflammation as a critical driver of immune dysfunction, premature appearance of aging-related diseases, and immune deficiency.

Cat. No. Product Name CAS No. Purity Chemical Structure
  • HY-W087907
    Acetylsalicylsalicylic acid 530-75-6 99.24%
    Acetylsalicylsalicylic acid exhibits immunogenicity that induces contact sensitivity and causes skin erythema and slight edema in guinea pigs.
    Acetylsalicylsalicylic acid
  • HY-W097268
    L-Lysinamide dihydrochloride 51127-08-3 99.90%
    L-Lysinamide dihydrochloride is an amide form of L-Lysine (HY-N0469). L-Lysinamide dihydrochloride can be conjugated with Cholesterol (HY-N0322) and L-ornithinamide for use as a DNA delivery agent.
    L-Lysinamide dihydrochloride
  • HY-W099331
    Monoethylglycinexylidide hydrochloride 7729-94-4 98.82%
    Monoethylglycinexylidide (MEGX) hydrochloride is a metabolite of Lidocain (HY-B0185) via oxidative N-deethylation of Lignocaine by liver cytochrome P-450 enzymes in the liver. Monoethylglycinexylidide has proven to be a highly sensitive indicator of hepatic dysfunction, especially in the field of liver transplantation.
    Monoethylglycinexylidide hydrochloride
  • HY-W109299
    Cedrol methyl ether 19870-74-7 98%
    Cedrol methyl ether is an active ingredient that can be extracted from ginger. Cedrol methyl ether has anti-inflammatory activity. Cedrol methyl ether can be used for research on hyperhidrosis and abnormal vaginal discharge.
    Cedrol methyl ether
  • HY-W121887
    Zomepirac acyl-O-β-D-glucuronide 75871-31-7 98%
    Zomepirac acyl-O-β-D-glucuronide (Zomepirac glucuronide) is a dipeptidyl peptidase IV Inhibitor. Zomepirac acyl-O-β-D-glucuronide is an unstable and chemically reactive metabolite of Zomepirac (HY-B0890A). Zomepirac acyl-O-β-D-glucuronide forms covalent adducts with cell membrane glycoproteins. Zomepirac acyl-O-β-D-glucuronide can be used for research on immunotoxicity.
    Zomepirac acyl-O-β-D-glucuronide
  • HY-W184893
    Atranol 526-37-4 99.48%
    Atranol is a strong contact allergen found in oak moss absolute (OMA). Atranol causes contact dermatitis by inducing immune system allergic reactions. Atranol is promising for research of etiology of contact dermatitis and cosmetic allergens.
    Atranol
  • HY-W265314
    Arvelexin 4837-74-5 98%
    Arvelexin is a biologically active compound. Arvelexin can be found in Brassica rapa L. (Brassicaceae). Arvelexin inhibits NF-κB activation and the expressions of IL-8. Arvelexin inhibits colonic inflammation.
    Arvelexin
  • HY-W268542
    4-Acetylaminoantipyrine 83-15-8 99.60%
    4-Acetylaminoantipyrine (4-AA) is a derivative of antipyrine (HY-B0171). 4-Acetylaminoantipyrine acts as a PGE2-dependent blocker and inhibitor of cyclooxygenase (COX). 4-Acetylaminoantipyrine can inhibit Cu/ZnSOD. 4-Acetylaminoantipyrine can spontaneously bind with bovine serum albumin (BSA) and alter its conformation.
    4-Acetylaminoantipyrine
  • HY-W345359
    PAF C-18:1 85966-90-1 99.9%
    PAF C-18:1 is a naturally occurring phospholipid produced by cells upon inflammatory responses. PAF C-18:1 is a chemoattractant, and induces human neutrophil chemotaxis.
    PAF C-18:1
  • HY-W354369
    1-(4-Fluorobenzyl)-1H-indazole-3-carboxylic acid 50264-63-6 99.90%
    1-(4-Fluorobenzyl)-1H-indazole-3-carboxylic acid (Compound 31) is a metabolite of AB-FUBINACA. 1-(4-Fluorobenzyl)-1H-indazole-3-carboxylic acid is a MRGPRX4 antagonist (IC50: >2.5 μM).
    1-(4-Fluorobenzyl)-1H-indazole-3-carboxylic acid
  • HY-W587806
    9-cis Retinol 22737-97-9
    9-cis Retinol is a precursor of 9-cis-Retinal (HY-W009310). 9-cis Retinol can inhibit 9-cis-Retinoic acid (HY-15128) synthesis in Hep G2 cells.
    9-cis Retinol
  • HY-W698462
    (S)-3-Hydroxymyristic acid 35683-15-9 99.73%
    (S)-3-Hydroxymyristic acid ((3S)-3-Hydroxytetradecanoic acid) is the enantiomer of (R)-3-hydroxytetradecanoic acid (a lipid A component) (HY-W288375), and enhances the inherent immune adjuvant activity of lipid A.
    (S)-3-Hydroxymyristic acid
  • HY-W744739
    Betulinic acid-d3 99.9%
    Betulinic acid-d3 (Lupatic acid-d3) is a deuterium labeled Betulinic acid (HY-10529). Betulinic acid is a natural pentacyclic triterpenoid, acts as a eukaryotic topoisomerase I inhibitor, with an IC50 of 5 μM, and possesses anti-HIV, anti-malarial, anti-inflammatory and anti-tumor properties. Betulinic acid can cross the blood-brain barrier.
    Betulinic acid-d3
  • HY-W750674
    Indole-3-carboxaldehyde-13C8
    Indole-3-carboxaldehyde-13C8 (3-Formylindole-13C8) is the 13C-labeled Indole-3-carboxaldehyde (HY-W007376). Indole-3-carboxaldehyde, a banlangen extract, is the product of the oxidative degradation of indole-3-acetic acid (IAA) by crude enzyme preparations from etiolated pea seedlings. Indole-3-carboxaldehyde is a biochemical used to prepare analogs of the indole phytoalexin cyclobrassinin. Indole-3-carboxaldehyde also enhances the epithelial barrier and anti-inflammatory activity in the intestinal tract.
    Indole-3-carboxaldehyde-13C8
  • HY-W778340
    16α-Hydroxy-11-keto prednisolone 3754-05-0 98%
    16α-Hydroxy-11-keto prednisolone (compound M-X) is a metabolite of Budesonide (HY-13580). Budesonide, an inhaled glucocortical steroid, is an orally active glucocorticoid receptor agonist. Budesonide is a widely used for study of asthma, rhinitis, and inflammatory bowel disease.
    16α-Hydroxy-11-keto prednisolone
  • HY-W782079
    Geraniol-d6 (Major) 1660976-93-1
    Geraniol-d6 (Major) is the deuterated labeled Geraniol (Major). Geraniol is an olefin terpene with oral activity. Geraniol inhibits cell proliferation and promotes apoptosis. Geraniol has antibacterial, antifungal, antioxidant, anti-inflammatory and antitumor activities. Geraniol can be used to study diabetes.
    Geraniol-d6 (Major)
  • HY-113008AS
    cis-Urocanic acid-13C3 99.46%
    cis-Urocanic acid-13C3 is the 13C-labeled cis-Urocanic acid. cis-Urocanic acid is a 5-HT2A receptor agonist. cis-Urocanic acid binds to 5-HT receptor with relatively high affinity (Kd=4.6 nM). cis-Urocanic acid is an immune modulator that induces immunosuppression by binding to the 5-HT2A receptor.
    cis-Urocanic acid-13C3
  • HY-113066AR
    Guanosine 5'-diphosphate disodium salt (Standard) 7415-69-2
    Guanosine 5'-diphosphate (disodium salt) (Standard) is the analytical standard of Guanosine 5'-diphosphate (disodium salt). This product is intended for research and analytical applications. Guanosine 5'-diphosphate (GDP) disodium salt, a purine nucleoside diphosphate, is interconverted to guanosine by the action of exonucleotidase and phosphorylation of nucleoside to guanine. Guanosine 5'-diphosphate disodium salt activates adenosine 5'-triphosphate-sensitive K+ channel and is used to study the kinetics and characteristics of GTPases such as those associated with G-protein coupled receptors (GPCR). Guanosine 5'-diphosphate disodium salt is a potential iron mobilizer, which prevents the Hepcidin (HY-P70400)-ferroportin interaction and modulates the interleukin-6 (IL-6)/stat-3 pathway. Elevated levels of guanosine 5’-diphosphate are associated with the pathogenesis of neurological diseases. Guanosine 5'-diphosphate disodium salt is promising for the research of inflammation, such as anemia of inflammation (AI).
    Guanosine 5'-diphosphate disodium salt (Standard)
  • HY-132187S1
    Sphingosylphosphorylcholine-d7 2260670-14-0 99.90%
    Sphingosylphosphorylcholine-d7 is the deuterium labeled Sphingosylphosphorylcholine (HY-132187).
    Sphingosylphosphorylcholine-d7
  • HY-160144S1
    (S)-Lomedeucitinib 2328068-38-6 99.09%
    (S)-Lomedeucitinib ((S)-BMS-986322) is a S-enantiomer of Lomedeucitinib (HY-160144S). Lomedeucitinib is a tyrosine protein kinase (TYK2) inhibitor.
    (S)-Lomedeucitinib
Cat. No. Product Name / Synonyms Application Reactivity