4-Acetylaminoantipyrine
Based on 1 Customer Validation
4-Acetylaminoantipyrine (4-AA) is a derivative of antipyrine (HY-B0171). 4-Acetylaminoantipyrine acts as a PGE2-dependent blocker and inhibitor of cyclooxygenase (COX). 4-Acetylaminoantipyrine can inhibit Cu/ZnSOD. 4-Acetylaminoantipyrine can spontaneously bind with bovine serum albumin (BSA) and alter its conformation.
For research use only. We do not sell to patients.
- Purity : 99.60%
- CAS No.: 83-15-8
- Formula: C13H15N3O2
- Molecular Weight:245.28
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Storage:Powder -20°C, 3 years ; In solvent -80°C, 6 months , -20°C, 1 month
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
Description
Chemical Information
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CAS No. 83-15-8
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Appearance Solid
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Molecular Weight 245.28
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Formula C13H15N3O2
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Color Off-white to light yellow
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SMILES
CC1=C(NC(C)=O)C(N(N1C)C2=CC=CC=C2)=O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Powder -20°C 3 years In solvent -80°C 6 months -20°C 1 month
Solvent & Solubility
In Vitro:
DMSO : 100 mg/mL (407.70 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (274 KB)
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SDS (393 KB)
- English - EN (393 KB)
- Français - FR (393 KB)
- Deutsch - DE (393 KB)
- Norwegian - NO (393 KB)
- Español - ES (393 KB)
- Swedish - SV (393 KB)
- Italian - IT (393 KB)
- Korean - KR (393 KB)
- Portuguese - PT (393 KB)
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Handling Instructions (2659 KB)
References
[1]. Berno CR, et al. Aminoantipyrine reduces toxic and genotoxic effects of doxorubicin, cisplatin, and cyclophosphamide in male mice. Mutat Res Genet Toxicol Environ Mutagen. 2016 Jul;805:19-24. [Content Brief]
[2]. Teng Y, et al. Insights into potentially toxic effects of 4-aminoantipyrine on the antioxidant enzyme copper-zinc superoxide dismutase. J Hazard Mater. 2013 Nov 15;262:318-24. [Content Brief]
[3]. Teng Y, et al. The interaction between 4-aminoantipyrine and bovine serum albumin: multiple spectroscopic and molecular docking investigations. J Hazard Mater. 2011 Jun [Content Brief]
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
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| DMSO | 1 mM | 4.0770 mL | 20.3849 mL | 40.7697 mL | 101.9243 mL |
| 5 mM | 0.8154 mL | 4.0770 mL | 8.1539 mL | 20.3849 mL | |
| 10 mM | 0.4077 mL | 2.0385 mL | 4.0770 mL | 10.1924 mL | |
| 15 mM | 0.2718 mL | 1.3590 mL | 2.7180 mL | 6.7950 mL | |
| 20 mM | 0.2038 mL | 1.0192 mL | 2.0385 mL | 5.0962 mL | |
| 25 mM | 0.1631 mL | 0.8154 mL | 1.6308 mL | 4.0770 mL | |
| 30 mM | 0.1359 mL | 0.6795 mL | 1.3590 mL | 3.3975 mL | |
| 40 mM | 0.1019 mL | 0.5096 mL | 1.0192 mL | 2.5481 mL | |
| 50 mM | 0.0815 mL | 0.4077 mL | 0.8154 mL | 2.0385 mL | |
| 60 mM | 0.0679 mL | 0.3397 mL | 0.6795 mL | 1.6987 mL | |
| 80 mM | 0.0510 mL | 0.2548 mL | 0.5096 mL | 1.2741 mL | |
| 100 mM | 0.0408 mL | 0.2038 mL | 0.4077 mL | 1.0192 mL |
4-Acetylaminoantipyrine Related Classifications
HY-W268542 Related Classifications
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