2. Inflammation/Immunology

Inflammation/Immunology

Inflammation/Immunology

Related Products

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The diseases caused by disorders of the immune system fall into two broad categories: immunodeficiency and autoimmunity. Immunotherapy is also often used in the immunosuppressed (such as HIV patients) and people suffering from other immune deficiencies or autoimmune diseases. This includes regulating factors such as IL-2, IL-10, IFN-α. Infection with HIV is characterized not only by development of profound immunodeficiency but also by sustained inflammation and immune activation. Chronic inflammation as a critical driver of immune dysfunction, premature appearance of aging-related diseases, and immune deficiency.

Cat. No. Product Name CAS No. Purity Chemical Structure
  • HY-P5923
    E70K 98%
    E70K is a CXCL8 C-terminal peptide with a substitution of glutamic acid (E) 70 with lysine (K). E70K can reduce neutrophil adhesion and migration during inflammation.
    E70K
  • HY-P5925
    Ssm spooky toxin 98%
    Ssm Spooky Toxin is found in Scolopendra mutilans that potently inhibits KCNQ (voltage-gated potassium channel family 7) channels, with IC50s of 2.8 μM, 5.26 μM and 0.1-0.3 M for Kv7.4, Kv1.3, and Shal channel, respectivily. Ssm Spooky Toxin inhibits cytokine generation by specifically acting on the KV1.3 channel in T cells. Ssm Spooky Toxin plays an essential role in the centipede’s circulatory system .
    Ssm spooky toxin
  • HY-P5929
    VnP-16 98%
    VnP-16 can promote bone formation by accelerating osteoblast differentiation and activity through direct interaction with β1 integrin followed by FAK activation.
    VnP-16
  • HY-P5942
    Pterinotoxin-2 98%
    Pterinotoxin-2 is a sodium channel inhibitor peptide toxin.
    Pterinotoxin-2
  • HY-P5952
    Bilaid B1 2393866-07-2 98%
    Bilaid B1 (Compound Bilaid 2b) is an analgesics compound
    Bilaid B1
  • HY-P6177
    SGP8 855790-98-6 98%
    SGP8 (IAVPGEVA) is an octapeptide produced by hydrolysis of soybean 11S globulin, which has the effects of regulating lipid metabolism, inflammation and fibrosis. SGP8 (IAVPGEVA) exhibits inhibitory activity against DPP4 and inhibits the JNK-c-Jun signaling pathway, and has the ability to inhibit non-alcoholic steatohepatitis (NASH).
    SGP8
  • HY-P6441
    KP-6 2102414-23-1 98%
    KP-6, a polypeptide, is a Wnt/β-catenin signal inhibitor. KP-6 inhibits TGF-β and blocks rush fibrosis signal path crucial in vivo. KP-6 suppresses Renal tissues damage and renal fibrosis, and reverse the course of disease of chronic kidney disease (CKD).
    KP-6
  • HY-P9942
    Sulesomab 167747-19-5
    Sulesomab (IMMU-MN3) is a murine monoclonal antibody fragment of the IgG1 class that binds to Normal Cross-Reactive Antigen-90 present on leukocytes. Sulesomab is cleared into infection nonspecifically through increased capillary membrane permeability.
    Sulesomab
  • HY-100084
    Methyl-3β-hydroxycholenate 20231-57-6 98%
    Methyl-3β-hydroxycholenate is a ROR gamma modulator extracted from patent US20110263046 A1, in figure 2.
    Methyl-3β-hydroxycholenate
  • HY-100087
    Budesonide impurity C 1040085-99-1 98.58%
    Budesonide impurity C is an impurity of Budesonide. Budesonide, an inhaled glucocortical steroid, is an orally active glucocorticoid receptor agonist.
    Budesonide impurity C
  • HY-100125
    Timegadine 71079-19-1 98%
    Timegadine, a new antiinflammatory agent, is found to be a potent, competitive inhibitor of cyclo-oxygenase (COX) and lipo-oxygenase, with IC50s ranging from 5 nM (washed rabbit platelets) to 20 μM (rat brain) for COX and 100 μM for lipo-oxygenase both in the cytosol fraction of horse platelet homogenates, and in washed rabbit platelets.
    Timegadine
  • HY-100139
    Diflumidone 22736-85-2 98%
    Diflumidone is a non-steroidal antiinflammatory agent.
    Diflumidone
  • HY-100142
    Clozic 22494-47-9 98%
    Clozic is a potential anti-arthritic agent.
    Clozic
  • HY-100146
    Pirazolac 71002-09-0 99.08%
    Pirazolac is a non-steroidal anti-inflammatory drug.
    Pirazolac
  • HY-100148
    ICI 211965 129424-08-4 98%
    ICI 211965 (ZM-211965) is a selective and orally potent 5-Lipoxygenase (5-LPO) inhibitor.
    ICI 211965
  • HY-100158
    FCE-20696 hydrochloride 83359-86-8 98%
    FCE-20696 hydrochloride is an orally active immunomodulator. FCE-20696 hydrochloride also shows anti-inflammation and anti-infection effects. FCE-20696 hydrochloride can be used for the researches of infection, inflammation and immunology, such as adjuvant arthritis.
    FCE-20696 hydrochloride
  • HY-100162
    TOK-8801 105963-46-0 98%
    TOK-8801 is a synthesized dihydroimidazothiazole carboxamide and is under development as an immunomodulator.
    TOK-8801
  • HY-100173
    DW-1350 491577-61-8 98%
    DW-1350 is a LTB4 receptor antagonist.
    DW-1350
  • HY-10017A
    (R)-SCH 546738 2181148-54-7 99.75%
    (R)-SCH 546738 is the R-isomer of SCH 546738 (HY-10017). SCH 546738 is an orally active and non-competitive antagonist for CXCR3 with Ki of 0.4 nM for human CXCR3 receptor.
    (R)-SCH 546738
  • HY-100191
    BMY-25271 78441-82-4 98%
    BMY-25271 is a histamine H2 receptor antagonist.
    BMY-25271
Cat. No. Product Name / Synonyms Application Reactivity