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Cat. No.: HY-P5942

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Pterinotoxin-2

Pterinotoxin-2 is a sodium channel inhibitor peptide toxin.

For research use only. We do not sell to patients.

Formula: C₁₅₆H₂₃₇N₄₅O₄₂S₇
Molecular Weight:3639.28

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Pterinotoxin-2 Chemical Structure

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Top Publications Citing

Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- Description
- IC₅₀ & Target
Chemical Information
Purity & Documentation
References
Calculators
Help & FAQs
Bioz

Biological Activity

Description

Pterinotoxin-2 is a sodium channel inhibitor peptide toxin^[1].

IC₅₀ & Target

Nav1.3

Nav1.7

All Sodium Channel Isoforms :

Chemical Information

Molecular Weight 3639.28
Formula C₁₅₆H₂₃₇N₄₅O₄₂S₇
Sequence

Tyr-Cys-Gln-Glu-Phe-Leu-Trp-Thr-Cys-Asp-Glu-Glu-Arg-Lys-Cys-Cys-Gly-Asp-Met-Val-Cys-Arg-Leu-Trp-Cys-Lys-Lys-Arg-Leu-NH2 (Disulfide bridge: Cys2-Cys16,Cys9-Cys21,Cys15-Cys25)
Sequence Shortening

YCQEFLWTCDEERKCCGDMVCRLWCKKRL-NH2 (Disulfide bridge: Cys2-Cys16,Cys9-Cys21,Cys15-Cys25)
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (260 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Marit Poffers, et al. Sodium Channel Nav1.3 Is Expressed by Polymorphonuclear Neutrophils during Mouse Heart and Kidney Ischemia InVivo and Regulates Adhesion, Transmigration, and Chemotaxis of Human and Mouse Neutrophils In Vitro. Anesthesiology. 2018 Jun;128(6):1151-1166. [Content Brief]

Calculators

Molarity Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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Dilution Calculator

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Keywords

100 mg

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