1. GPCR/G Protein Immunology/Inflammation
  2. CXCR
  3. (R)-SCH 546738

(R)-SCH 546738 is the R-isomer of SCH 546738 (HY-10017). SCH 546738 is an orally active and non-competitive antagonist for CXCR3 with Ki of 0.4 nM for human CXCR3 receptor.

For research use only. We do not sell to patients.

(R)-SCH 546738 Chemical Structure

(R)-SCH 546738 Chemical Structure

CAS No. : 2181148-54-7

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Based on 1 publication(s) in Google Scholar

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Description

(R)-SCH 546738 is the R-isomer of SCH 546738 (HY-10017). SCH 546738 is an orally active and non-competitive antagonist for CXCR3 with Ki of 0.4 nM for human CXCR3 receptor[1].

Molecular Weight

492.44

Formula

C23H31Cl2N7O

CAS No.
SMILES

O=C(N)C1=NC(Cl)=C(N2CCN(C3CCN(CC4=CC=C(Cl)C=C4)CC3)[C@H](CC)C2)N=C1N

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Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation
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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Product Name:
(R)-SCH 546738
Cat. No.:
HY-10017A
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