2. Inflammation/Immunology

Inflammation/Immunology

Inflammation/Immunology

Related Products

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The diseases caused by disorders of the immune system fall into two broad categories: immunodeficiency and autoimmunity. Immunotherapy is also often used in the immunosuppressed (such as HIV patients) and people suffering from other immune deficiencies or autoimmune diseases. This includes regulating factors such as IL-2, IL-10, IFN-α. Infection with HIV is characterized not only by development of profound immunodeficiency but also by sustained inflammation and immune activation. Chronic inflammation as a critical driver of immune dysfunction, premature appearance of aging-related diseases, and immune deficiency.

Cat. No. Product Name CAS No. Purity Chemical Structure
  • HY-129113R
    α-?Chaconine (Standard) 20562-03-2
    α-Chaconine (Standard) is the analytical standard of α-Chaconine. This product is intended for research and analytical applications. α-Chaconine inhibits the expressions of COX-2, IL-1β, IL-6, and TNF-α at the transcriptional level. α-Chaconine inhibits the LPS-induced expressions of iNOS and COX-2 at the protein and mRNA levels and their promoter activities in RAW 264.7 macrophages. Anti-inflammatory effects.
    α-?Chaconine (Standard)
  • HY-129440R
    N-(p-Coumaroyl) Serotonin (Standard) 68573-24-0 98%
    N-(p-Coumaroyl) Serotonin (Standard) is the analytical standard of N-(p-Coumaroyl) Serotonin (HY-129440). This product is intended for research and analytical applications. N-(p-Coumaroyl) Serotonin is an orally active polyphenol found in safflower seeds with potent anti-inflammatory, antioxidant, and antitumor activities. N-(p-Coumaroyl) Serotonin suppresses NF‑κB, TLR4/MyD88 and MAPK signaling, activates NQO1/HO‑1 pathways, and inhibits pro‑inflammatory cytokines, iNOS and COX‑2 and ROS production. N-(p-Coumaroyl) Serotonin induces S‑phase arrest and apoptosis in glioblastoma cells, reduces atherosclerotic lesions, and alleviates renal and vascular injuries. N-(p-Coumaroyl) Serotonin acts as a vasodilator, regulates calcium dynamics. N-(p-Coumaroyl) Serotonin can be used for the research of neurodegenerative diseases, atherosclerosis, glioblastoma, and acute renal failure.
    N-(p-Coumaroyl) Serotonin (Standard)
  • HY-129524R
    Ethylene dimethanesulfonate (Standard) 4672-49-5
    Ethylene dimethanesulfonate (Standard) is the analytical standard of Ethylene dimethanesulfonate. This product is intended for research and analytical applications. Ethylene dimethane sulfonate is a mild alkylating, non-volatile methanesulfonic diester of ethylene glycol. Ethylene dimethanesulfonate has selective pro-apoptotic effects on LCs.
    Ethylene dimethanesulfonate (Standard)
  • HY-130046R
    16-Epiestriol (Standard) 547-81-9
    16-Epiestriol (Standard) is the analytical standard of 16-Epiestriol (HY-130046). This product is intended for research and analytical applications. 16-Epiestriol (16-epi-Estriol; 16β,17β-Estriol) is a natural stereoisomer of estriol and an anti-inflammatory agent that targets UGT. The Ki values of 16-Epiestriol against human UGT1A10 and UGT2B7 are 98.1 μM and 162 μM, respectively. As a glucuronidation substrate, 16-Epiestriol can be modified at the 3-OH, 16-OH and 17-OH sites by various UGT enzymes; in liver microsomes, the modification mainly occurs at the 16-OH and 17-OH sites, while reactions take place at all three sites in intestinal microsomes. 16-Epiestriol acts on the phase II inflammatory process by blocking edema mediated by prostaglandins and leukocyte infiltration. It lacks glycogenic activity or any effect on blood glucose levels, and serves as an important candidate molecule in the research of inflammatory diseases.
    16-Epiestriol (Standard)
  • HY-130313R
    Sodium lauroyl glutamate (Standard) 29923-31-7
    Sodium lauroyl glutamate (Standard) is the analytical standard of Sodium lauroyl glutamate. This product is intended for research and analytical applications. Sodium lauroyl glutamate is an anionic amino acid surfactant. Sodium lauroyl glutamate has the irritant contact dermatitis potential, and possible anti-irritating potential in a surfactant mixture on human skin.
    Sodium lauroyl glutamate (Standard)
  • HY-130320A
    Monophosphoryl lipid A free acid 960324-04-3 98%
    Monophosphoryl lipid A (free acid) is a toll-like receptor 4 agonist. Monophosphoryl lipid A (free acid) is derived from the cell wall of nonpathogenic Salmonella. Monophosphoryl lipid A (free acid) can be used for the research of immunization and vaccine.
    Monophosphoryl lipid A free acid
  • HY-13038AR
    Fostamatinib (Standard) 901119-35-5 98%
    Fostamatinib (Standard) is the analytical standard of Fostamatinib. This product is intended for research and analytical applications. Fostamatinib (R788) is the oral proagent of the active compound R406. R406 is an orally available and competitive Syk/FLT3 inhibitor with a Ki of 30 nM and an IC50 of 41 nM. R406 also inhibits Lyn (IC50=63 nM) and Lck (IC50=37 nM).
    Fostamatinib (Standard)
  • HY-13038BR
    Fostamatinib disodium hexahydrate (Standard) 914295-16-2
    Fostamatinib (disodium hexahydrate) (Standard) is the analytical standard of Fostamatinib (disodium hexahydrate). This product is intended for research and analytical applications. Fostamatinib (R788) disodium hexahydrate is the oral proagent of the active compound R406. R406 is an orally available and competitive Syk/FLT3 inhibitor with a Ki of 30 nM and an IC50 of 41 nM. R406 also inhibits Lyn (IC50=63 nM) and Lck (IC50=37 nM).
    Fostamatinib disodium hexahydrate (Standard)
  • HY-131106S
    Clorprenaline-d7 2748354-86-9 98%
    Clorprenaline-d7 is a deuterium labeled Clorprenaline. Clorprenaline is a β2-adrenergic receptor agonist that is implicated in bronchial expansion. Clorprenaline has the potential for asthma research.
    Clorprenaline-d7
  • HY-131118R
    Desmethyl Ketoprofen (Standard) 22071-22-3
    Desmethyl Ketoprofen (Standard) is the analytical standard of Desmethyl Ketoprofen. This product is intended for research and analytical applications.
    Desmethyl Ketoprofen (Standard)
  • HY-131145R
    Brombuterol hydrochloride (Standard) 21912-49-2
    Brombuterol (hydrochloride) (Standard) is the analytical standard of Brombuterol (hydrochloride). This product is intended for research and analytical applications. Brombuterol hydrochloride (Bromobuterol hydrochloride) is a β-adrenergic receptor agonist.
    Brombuterol hydrochloride (Standard)
  • HY-131150R
    Ristomycin sulfate (Standard) 11140-99-1
    Norfenefrine (hydrochloride) (Standard) is the analytical standard of Norfenefrine (hydrochloride). This product is intended for research and analytical applications. Norfenefrine hydrochloride is an orally active, endogenously found α-adrenergic agonist and can be used for the research of female stress incontinence.
    Ristomycin sulfate (Standard)
  • HY-131259R
    Ibuprofen Impurity F (Standard) 65322-85-2
    Ibuprofen Impurity F (Standard) is the analytical standard of Ibuprofen Impurity F. This product is intended for research and analytical applications. Ibuprofen Impurity F is an Ibuprofen impurity. Ibuprofen is an anti-inflammatory inhibitor targeting COX-1 and COX-2 with IC50s of 13 μM and 370 μM, respectively.
    Ibuprofen Impurity F (Standard)
  • HY-131260R
    Ibuprofen Impurity K (Standard) 43153-07-7
    Ibuprofen Impurity K (Standard) is the analytical standard of Ibuprofen Impurity K. This product is intended for research and analytical applications. Ibuprofen Impurity K is an Ibuprofen impurity. Ibuprofen is an anti-inflammatory inhibitor targeting COX-1 and COX-2 with IC50s of 13 μM and 370 μM, respectively.
    Ibuprofen Impurity K (Standard)
  • HY-131261R
    Ibuprofen alcohol (Standard) 36039-36-8
    Ibuprofen alcohol (Standard) is the analytical standard of Ibuprofen alcohol. This product is intended for research and analytical applications. Ibuprofen alcohol, a nonsteroidal antiinflammatory agent (NSAID), exhibits very little activity for acid-sensing ion channels (ASICs).
    Ibuprofen alcohol (Standard)
  • HY-131495R
    (S)-6-O-Desmethylnaproxen (Standard) 52079-10-4
    (S)-6-O-Desmethylnaproxen (Standard) is the analytical standard of (S)-6-O-Desmethylnaproxen. This product is intended for research and analytical applications. (S)-6-O-Desmethylnaproxen ((S)-6-Desmethyl Naproxen) is a metabolite of the non-steroidal anti-inflammatory drug (NSAID) and COX inhibitor (+)-naproxen ((S)-naproxen). (S)-6-O-Desmethylnaproxen is formed from (S)-naproxen by the cytochrome P450 (CYP) isoforms CYP1A2 and CYP2C9.
    (S)-6-O-Desmethylnaproxen (Standard)
  • HY-131597B
    8-Oxo-GTP tetrasodium
    8-Oxo-GTP (8-Hydroxyguanosine triphosphate) tetrasodium is an oxidized oxidized guanine nucleotides and acts as a crucial biomarker for oxidative stress.
    8-Oxo-GTP tetrasodium
  • HY-132269R
    Isoflupredone (Standard) 338-95-4
    Isoflupredone (Standard) is the analytical standard of Isoflupredone. This product is intended for research and analytical applications. Isoflupredone belongs to the class of corticosteroids and exerts its effect by binding to glucocorticoid and mineralocorticoid receptors of animals, such as horses. Isoflupredone can be used in wide range of conditions, such as infection and inflammatory diseases.
    Isoflupredone (Standard)
  • HY-133026R
    N-Acetylcarnosine (Standard) 56353-15-2 98%
    N-Acetylcarnosine (Standard) is the analytical standard of N-Acetylcarnosine. This product is intended for research and analytical applications. N-Acetylcarnosine, a natural histidine-containing dipeptide, is a source of pharmacological principal L-carnosine. N-Acetylcarnosine is a potent ophthalmic agent in human cataracts.
    N-Acetylcarnosine (Standard)
  • HY-133114R
    Ezetimibe ketone (Standard) 191330-56-0 98%
    Ezetimibe ketone (Standard) is the analytical standard of Ezetimibe ketone (HY-133114). This product is intended for research and analytical applications. Ezetimibe ketone is an orall active Nrf2 activator and ROS inhibitor. Ezetimibe ketone attenuates H2O2-induced reactive oxygen species production and reduces H2O2-induced apoptosis in renal tubular epithelial cells. Ezetimibe ketone suppresses renal tubular injury and inflammation.
    Ezetimibe ketone (Standard)
Cat. No. Product Name / Synonyms Application Reactivity