Ezetimibe ketone (Standard)
Ezetimibe ketone (Standard) is the analytical standard of Ezetimibe ketone (HY-133114). This product is intended for research and analytical applications. Ezetimibe ketone is an orall active Nrf2 activator and ROS inhibitor. Ezetimibe ketone attenuates H2O2-induced reactive oxygen species production and reduces H2O2-induced apoptosis in renal tubular epithelial cells. Ezetimibe ketone suppresses renal tubular injury and inflammation.
商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- 純度 : 98%
- CAS 番号: 191330-56-0
- 分子式: C24H19F2NO3
- 分子量:407.41
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保管条件:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Product Information
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化学情報
- 純度とドキュメンテーション
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Help & FAQs
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HY-133114
Ezetimibe ketoneNrf2 Activator/ROS Inhibitor -
HY-100523
ML385Nrf2 Inhibitor -
HY-12212
OmaveloxoloneNrf2 Activator -
HY-N1913
DanshensuNrf2/HO-1 Activator -
HY-Z0548
Methyl 3,4-dihydroxybenzoate -
HY-136059
Desfluoro-ezetimibeCholesterol Absorption Inhibitor -
HY-17376
EzetimibeCholesterol Absorption Inhibitor -
HY-13755
SulforaphaneKeap1/Nrf2/ARE Inducer -
HY-15725
CDDO-ImNrf2 Activator -
HY-N0509
AstilbinTNF Receptor Inhibitor -
HY-N2292
KinsenosideAnti-Apoptosis Agent -
HY-N1902
4-Hydroxyphenylacetic acidEndogenous Metabolite
Product Information
説明
アプリケーション
The compound is the grade of analytical standard, which is the reference standard supplied assay. It is commonly used in qualitative, quantitative and methodological research experiments in HPLC, GC and MS.
化学情報
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CAS 番号 191330-56-0
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分子量 407.41
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分子式 C24H19F2NO3
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SMILES
O=C1N(C2=CC=C(F)C=C2)[C@H](C3=CC=C(O)C=C3)[C@H]1CCC(C4=CC=C(F)C=C4)=O
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別名
EZM-K (Standard)
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
Please store the product under the recommended conditions in the Certificate of Analysis.
純度とドキュメンテーション
参考文献
[2]. Lee DH, et al. Ezetimibe, an NPC1L1 inhibitor, is a potent Nrf2 activator that protects mice from diet-induced nonalcoholic steatohepatitis. Free Radic Biol Med. 2016 Sep 12;99:520-532. [Content Brief]
[3]. Chang E, et al. Ezetimibe improves hepatic steatosis in relation to autophagy in obese and diabetic rats. World J Gastroenterol. 2015 Jul 7;21(25):7754-63. [Content Brief]
Calculators
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
Ezetimibe ketone (Standard) 関連分類
HY-133114R 関連分類
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