8-Oxo-GTP tetrasodium
8-Oxo-GTP (8-Hydroxyguanosine triphosphate) tetrasodium is an oxidized oxidized guanine nucleotides and acts as a crucial biomarker for oxidative stress.
For research use only. We do not sell to patients.
- Formula: C10H12N5Na4O15P3
- Molecular Weight:627.11
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
Chemical Information
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Molecular Weight 627.11
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Formula C10H12N5Na4O15P3
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SMILES
O[C@H]1[C@@H](O)[C@H](N2C(N=C(N)NC3=O)=C3N=C2O)O[C@@H]1COP(OP(OP(O[Na])(O[Na])=O)(O[Na])=O)(O[Na])=O
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Synonyms
8-Hydroxyguanosine triphosphate tetrasodium
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
[1]. Patil AG, et al. Mycobacterium tuberculosis MutT1 (Rv2985) and ADPRase (Rv1700) proteins constitute a two-stage mechanism of 8-oxo-dGTP and 8-oxo-GTP detoxification and adenosine to cytidine mutation avoidance. J Biol Chem. 2013 Apr 19;288(16):11252-62. [Content Brief]
[2]. Li Y, et al. The role of DNA and RNA guanosine oxidation in cardiovascular diseases. Pharmacol Res. 2024 Jun;204:107187. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)