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TBHQ (Synonyms: tert-Butylhydroquinone)

Cat. No.: HY-100489 Purity: >98.0%
Handling Instructions

TBHQ is an antioxidant that activates Nrf2.

For research use only. We do not sell to patients.

TBHQ Chemical Structure

TBHQ Chemical Structure

CAS No. : 1948-33-0

Size Price Stock Quantity
Free Sample (0.5-1 mg)   Apply now  
10 mM * 1 mL in DMSO USD 66 In-stock
Estimated Time of Arrival: December 31
1 g USD 60 In-stock
Estimated Time of Arrival: December 31
5 g   Get quote  
10 g   Get quote  

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Customer Review

    TBHQ purchased from MCE. Usage Cited in: Biochem Biophys Res Commun. 2018 Jun 7;500(3):790-796.

    Macrophages are isolated from wild-type mice, treated with tBHQ (100 μM) or not, and induced for 3 h using LPS, IFN-g, IL-4 or IL-13. Western blot analysis of the expression of Nrf2, p65 subunit of NF-kB, phosphorylated p65 and PPARg in the cytoplasm and nucleus.

    TBHQ purchased from MCE. Usage Cited in: Front Pharmacol. 2018 Jun 6;9:540.

    BHQ promotes higher protein expression of Nrf2 in a time-dependent manner in neonatal rat cardiac fibroblasts (NRCF) while notably downregulated collagen I and collagen III.
    • Biological Activity

    • Technical Information

    • Purity & Documentation

    • References


    TBHQ is an antioxidant that activates Nrf2.

    Solvent & Solubility
    In Vitro: 

    DMSO : ≥ 56.66 mg/mL (340.87 mM)

    *"≥" means soluble, but saturation unknown.

    Stock Solutions
    Concentration Solvent Mass 1 mg 5 mg 10 mg
    1 mM 6.0161 mL 30.0806 mL 60.1612 mL
    5 mM 1.2032 mL 6.0161 mL 12.0322 mL
    10 mM 0.6016 mL 3.0081 mL 6.0161 mL
    *Please refer to the solubility information to select the appropriate solvent.
    Molecular Weight




    CAS No.




    Powder -20°C 3 years
      4°C 2 years
    In solvent -80°C 6 months
      -20°C 1 month

    Room temperature in continental US; may vary elsewhere

    • Molarity Calculator

    • Dilution Calculator

    The molarity calculator equation

    Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

    Mass   Concentration   Volume   Molecular Weight *
    = × ×

    The dilution calculator equation

    Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

    This equation is commonly abbreviated as: C1V1 = C2V2

    Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
    × = ×
    C1   V1   C2   V2

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    Cat. No.: HY-100489