1. Signaling Pathways
  2. GPCR/G Protein
    Neuronal Signaling
  3. 5-HT Receptor
  4. 5-HT3 Receptor Isoform
  5. 5-HT3 Receptor Agonist

5-HT3 Receptor Agonist

5-HT3 Receptor Agonists (11):

Cat. No. Product Name Effect Purity
  • HY-19358
    2-Methyl-5-HT
    Agonist 98.73%
    2-Methyl-5-HT (2-Methyl-5-hydroxytryptamine) is a potent and selective 5-HT3 receptor agonist.
  • HY-19650
    Pumosetrag Hydrochloride
    Agonist 99.77%
    Pumosetrag Hydrochloride (MKC-733; DDP-733) is an orally available 5-HT3 partial agonist developed for the treatment of irritable bowel syndrome and gastroesophageal reflux disease.
  • HY-100820
    Sarizotan
    Agonist 98.74%
    Sarizotan (EMD 128130) is an orally active serotonin 5-HT1A receptor and dopamine receptor agonist.
  • HY-13788
    LY 344864
    Agonist 98.93%
    LY 344864 is a selective, orally active 5-HT1F receptor agonist with a Ki of 6 nM.
  • HY-101331
    Phenylbiguanide
    Agonist ≥98.0%
    Phenylbiguanide is a 5-HT3 receptor selective agonist with an EC50 of 3.0±0.1 μM.
  • HY-112707
    AM9405
    Agonist
    AM9405 is a novel peripherally active cannabinoid type 1 (CB1) and serotonin type 3 receptor agonist.
  • HY-19358A
    2-Methyl-5-HT hydrochloride
    Agonist
    2-Methyl-5-HT hydrochloride (2-Methyl-5-hydroxytryptamine hydrochloride) is a potent and selective 5-HT3 receptor agonist.
  • HY-59201A
    A-582941 dihydrochloride
    Agonist
    A-582941 dihydrochloride is a potent, selective and brain-penetrant partial agonist of α7 nAChR, with Kis of 10.8 and 16.7 nM in rat brain membranes and human frontal cortex, respectively.
  • HY-13788B
    LY 344864 hydrochloride
    Agonist
    LY 344864 hydrochloride is a selective, orally active 5-HT1F receptor agonist with a Ki of 6 nM.
  • HY-14442
    ML 10302 hydrochloride
    Agonist
    ML 10302 hydrochloride is a potent and selective 5-HT4 receptor agonist, with an EC50 of 4 nM.
  • HY-19358B
    2-Methyl-5-HT maleate
    Agonist
    2-Methyl-5-HT maleate (2-Methyl-5-hydroxytryptamine maleate) is a potent and selective 5-HT3 receptor agonist.