1. Signaling Pathways
  2. Anti-infection
  3. Bacterial

Bacterial

Anything that destroys bacteria or suppresses their growth or their ability to reproduce. Heat, chemicals such as chlorine, and antibiotic drugs all have antibacterial properties. Many antibacterial products for cleaning and handwashing are sold today. Such products do not reduce the risk for symptoms of viral infectious diseases in otherwise healthy persons. This does not preclude the potential contribution of antibacterial products to reducing symptoms of bacterial diseases in the home.

Cat. No. Product Name Effect Purity Chemical Structure
  • HY-122069
    NSC177365
    Inhibitor
    NSC177365 (NSC 1) is a CcrM inhibitor. NSC177365 is a competitive DNA inhibitor and disrupts DNA binding. NSC177365 has antibacterial activity, with IC50s of 2.3 and 14.6 μM for C. crescentus and M. lincolnii respectively. NSC177365 reverses several neurodegenerative disorders and serve as an anticancer agent.
    NSC177365
  • HY-N14589
    Resorcinomycin A
    Inhibitor
    Resorcinomycin A is an antibiotic with strong anti-mycobacterium effect and weak anti-mycoplasma effect.
    Resorcinomycin A
  • HY-P10210
    Paenilagicin
    Inhibitor
    Paenilagicin is a Gram-positive active antibiotic with a unique diphosphorylated prenyl binding mechanism that does not induce drug resistance. Paenilagicin exhibits a MIC value of 2 μg/mL against multidrug-resistant Gram-positive bacteria.
    Paenilagicin
  • HY-B1127R
    Betamipron (Standard)
    Inhibitor
    Betamipron (Standard) is the analytical standard of Betamipron (HY-B1127). This product is intended for research and analytical applications. Betamipron (N-benzoyl-β-alanine) is a carbapenem β-lactam antibiotic with antibacterial activity against most Gram-positive and Gram-negative aerobic and anaerobic bacteria. Betamipron can target and inhibit renal organic anion transporters, alleviate renal injury caused by Cisplatin (HY-17394), without interfering with the biological activity of cisplatin. Betamipron is often used in combination with panipenem, which can attenuate the renal effects induced by panipenem and slightly promote the proliferation of Clostridium difficile in the cecum. Betamipron can be used in studies related to renal injury and bacterial infection.
    Betamipron (Standard)
  • HY-N6869R
    Dehydroabietic acid (Standard)
    Inhibitor
    Dehydroabietic acid (Standard) is the analytical standard of Dehydroabietic acid. This product is intended for research and analytical applications. Dehydroabietic acid is a diterpene resin acid that can be isolated from Pinus and Picea. Dehydroabietic acid has anti-bacterial, anti-fungal, anti-inflammatory, and anticancer activities. Dehydroabietic acid is a dual PPAR-α/γ agonist and PPAR-γ partial agonist, which can attenuate insulin resistance (IR) and hepatic steatosis induced by HFD-consumption in mice.
    Dehydroabietic acid (Standard)
  • HY-144282
    MsbA-IN-4
    Inhibitor
    MsbA-IN-4 (compound 32) is a potent and highly selective MsbA inhibitor with an IC50 value of 3 nM. MsbA-IN-4 has inhibitory activity against Escherichia coli with a MIC of 12 μM.
    MsbA-IN-4
  • HY-17028A
    (Rac)-Besifloxacin hydrochloride
    Inhibitor
    (Rac)-Besifloxacin Hydrochloride is a fourth generation fluoroquinolone antibiotic. (Rac)-Besifloxacin Hydrochloride is a DNA gyrase and topoisomerase IV inhibitor. (Rac)-Besifloxacin Hydrochloride has broad-spectrum antibacterial activity, it is effective against Gram-negative and Gram-positive aerobic and anaerobic strains and reduces the incidence of drug resistance. (Rac)-Besifloxacin Hydrochloride has anti-inflammatory activity. Besifloxacin Hydrochloride can be used in bacterial conjunctivitis research.
    (Rac)-Besifloxacin hydrochloride
  • HY-N9448R
    Lacto-N-tetraose (Standard)
    Inhibitor
    Ethyl 2-chloronicotinate (Standard) is the analytical standard of Ethyl 2-chloronicotinate. This product is intended for research and analytical applications. Ethyl 2-chloronicotinate is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
    Lacto-N-tetraose (Standard)
  • HY-115388
    Rodaplutin
    Inhibitor
    Rodaplutin (Sch 36605) is a ribosomal peptide antibiotic. Rodaplutin demonstrates anti-inflammatory effects by suppressing inflammatory mediator release in animal models. Rodaplutin is promising for research of infections and inflammatory diseases.
    Rodaplutin
  • HY-146190
    Callophycin A
    Inhibitor
    Callophycin A, a red seaweed derived metabolite, possessing potent activity against Candida albicans with MIC of 62.5~250 mg/L. Callophycin A significantly reduces fungal burden of vaginal candidiasis induced mice, also decreases inflammatory response and immune molecules.
    Callophycin A
  • HY-178802
    Antitubercular agent-53
    Inhibitor
    Antitubercular agent-53 (Compound 5b) is an antitubercular agent and antibacterial agent. Antitubercular agent-53 shows antitubercular activity against M. tuberculosis H37RV with an MIC of 4 μg/mL.
    Antitubercular agent-53
  • HY-163906
    Anti-MRSA agent 16
    Inhibitor
    Anti-MRSA agent 16 (Compound 4) is an inhibitor of methicillin-resistant Staphylococcus aureus (MRSA). Anti-MRSA agent 16 is effective in combination with oxacillin or meropenem in infected mice.
    Anti-MRSA agent 16
  • HY-123095
    TS 155-2
    Inhibitor
    TS 155-2 (JBIR 100), an antimicrobial agent, is a Bafilomycin analogue and an antibiotic. TS 155-2 can be isolated from a culture of Streptomyces sp. TS 155-2 inhibits V-ATPase activity. V-ATPase is correlated with an increasing number of diseases such as osteopetrosis, male infertility and renal acidosis.
    TS 155-2
  • HY-161485
    Gentamicin/BSA
    Inhibitor
    Gentamicin/BSA is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
    Gentamicin/BSA
  • HY-P11095
    Pelteobagrin
    Inhibitor
    Pelteobagrin is a broad-spectrum antimicrobial peptide targeting Gram-positive bacteria, Gram-negative bacteria, and fungi (MIC=2-16 μg/mL). Pelteobagrin exerts bactericidal activity via non-competitive disruption of cell wall and cytoplasmic membrane integrity. Pelteobagrin is promising for research of infectious diseases.
    Pelteobagrin
  • HY-N0216S6
    Benzoic acid-13C7
    Inhibitor
    Benzoic acid-13C7 is the 13C-labeled Benzoic acid (HY-N0216). Benzoic acid is an aromatic alcohol existing naturally in many?plants?and is a common additive to food, drinks, cosmetics and?other?products. It acts as?preservatives?through inhibiting both?bacteria?and?fungi.
    Benzoic acid-<sup>13</sup>C<sub>7</sub>
  • HY-105470
    BMY-28271
    Inhibitor
    BMY-28271 is an orally active cephalosporin. BMY-28271 has a widely expanded spectrum with high activity against gram-positive and gram-negative bacteria. BMY-28271 is a poor substrate for various beta-lactamases. BMY-28271 can be used for the research of infection.
    BMY-28271
  • HY-B1773AR
    Sodium propionate (Standard)
    Inhibitor
    Sodium propionate (Standard) is the analytical standard of Sodium propionate. This product is intended for research and analytical applications. Sodium propionate is an orally active short-chain fatty acid. Sodium propionate can be produced by intestinal bacteria from the metabolism of dietary fiber. Sodium propionate increases PPAR-γ, inhibits NF-κB activation, and reduces COX-2 expression and NO production. Sodium propionate also induces Apoptosis and Autophagy. Sodium propionate reduces HSV-1-induced keratitis. Sodium propionate has anticancer effects against glioblastoma. Sodium propionate exhibits neuroprotective, antioxidant, and anti-inflammatory activities. Sodium propionate can be used in the research of spinal cord injury and Alzheimer's disease.
    Sodium propionate (Standard)
  • HY-117746
    KSK120
    Inhibitor
    KSK120 is a potent inhibitor of drug-resistant infections with specific activity against Chlamydia trachomatis (C. trachomatis). KSK120 inhibits the developmental cycle of C. trachomatis, thereby reducing the infectivity of progeny bacteria. KSK120 targets the glucose-6-phosphate (G-6P) metabolic pathway of C. trachomatis, showing its potential application in antimicrobial inhibition. The mechanism of KSK120 may involve inhibition of the transcriptional machinery, which provides new ideas for the development of specific drugs against C. trachomatis infection.
    KSK120
  • HY-W769991
    Lactate sodium-13C2
    Inhibitor
    Lactic acid-13C2 (DL-Lactic acid-13C2) sodium is the 13C-labeled Lactic acid sodium . Lactic acid (DL-Lactic acid) sodium is a hydroxycarboxylic acid receptor 1 (HCAR1) activator and an epigenetic modulator inducing lysine residues lactylation. Lactic acid sodium is a glycolysis end-product, bridging the gap between glycolysis and oxidative phosphorylation. Lactic acid sodium is an oncometabolite and has immune protective role of lactate in anti-tumor immunity. Lactic acid sodium also has antimicrobial activity, which can be used as a food preservative.
    Lactate sodium-<sup>13</sup>C<sub>2</sub>
Cat. No. Product Name / Synonyms Application Reactivity