2. Signaling Pathways
  3. Anti-infection
  4. Bacterial

Bacterial

Bacterial

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Anything that destroys bacteria or suppresses their growth or their ability to reproduce. Heat, chemicals such as chlorine, and antibiotic drugs all have antibacterial properties. Many antibacterial products for cleaning and handwashing are sold today. Such products do not reduce the risk for symptoms of viral infectious diseases in otherwise healthy persons. This does not preclude the potential contribution of antibacterial products to reducing symptoms of bacterial diseases in the home.

Cat. No. Product Name Effect Purity Chemical Structure
  • HY-143483
    NBTIs-IN-5
    		Inhibitor
    NBTIs-IN-5 (Compound 5r) is a NBTI (Novel Bacterial Topoisomerase Inhibitor) DNA gyrase inhibitor with an IC50 of 1.5 μM against Mycobacterium abscessus (Mabs) DNA gyrase. NBTIs-IN-5 inhibits Mabs bamboo bacterial growth with an MIC90 of 0.4 μM.
    NBTIs-IN-5
  • HY-114816S
    N-butyryl-L-Homoserine lactone-d5
    		Inhibitor
    N-butyryl-L-Homoserine lactone-d5 is the deuterium labeled N-Butanoyl-L-homoserine lactone. N-Butanoyl-L-homoserine lactone (C4-HSL) is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). N-Butanoyl-L-homoserine lactone has antibacterial activity and is used in antibacterial biofilm. N-Butanoyl-L-homoserine lactone aptamers blocks qurom sensing and inhibits biofilm formation in Pseudomonas aeruginosa.
    N-butyryl-L-Homoserine lactone-d<sub>5</sub>
  • HY-N8507
    Tunicamycin B
    		Inhibitor
    Tunicamycin B is a Tunicamycin (HY-A0098) derivative with antimicrobial activity. Tunicamycin B shows antibacterial activity against Bacillus thuringiensis BT01 and B. thuringiensis W102 (MICs of 0.125 and 0.063 μg/mL, respectively) and antifungal activity against Candida albicans ATCC 96901 and C. albicans CMCC (F) 98001 (MICs of 8.0 and 4.0 μg/mL, respectively). Tunicamycin B can be used for antimicrobial research.
    Tunicamycin B
  • HY-B0356BS
    Ciprofloxacin-d8 hydrochloride monohydrate
    		Inhibitor
    Ciprofloxacin-d8 (hydrochloride monohydrate) is the deuterium labeled Ciprofloxacin (hydrochloride monohydrate). Ciprofloxacin hydrochloride is a fluoroquinolone antibiotic, exhibiting potent antibacterial activity.
    Ciprofloxacin-d<sub>8</sub> hydrochloride monohydrate
  • HY-152250
    Antibacterial agent 132
    		Inhibitor
    Antibacterial agent 132 has anticandidal effects against C. parapsilosis (ATCC 22019) and C. krusei (ATCC 6258) with MIC90 values of <0.06 μg/mL and 62.50 μg/mL, respectively. Antibacterial agent 132 inhibits aromatase enzyme with an IC50 of 0.047μM.
    Antibacterial agent 132
  • HY-149925
    DNA Gyrase-IN-6
    		Inhibitor
    Antibacterial agent 138 is a benzothiazole inhibitor of bacterial DNA gyrase and topoisomerase IV. Antibacterial agent 138 exhibits favorable solubility and plasma protein binding. Antibacterial agent 138 has antibacterial activity against Gram-positive and Gram-negative strains. Antibacterial agent 138 is a dual GyrB and ParE inhibitor.
    DNA Gyrase-IN-6
  • HY-B0466R
    Cloxacillin sodium monohydrate (Standard)
    		Inhibitor
    Cloxacillin (sodium monohydrate) (Standard) is the analytical standard of Cloxacillin (sodium monohydrate). This product is intended for research and analytical applications. Cloxacillin sodium monohydrate is an orally active antibacterial agent and β-lactamase inhibitor with an IC50 of 0.04 μM. Cloxacillin sodium monohydrate can suppress the S. aureus-induced inflammatory response by inhibiting the activation of MAPKs, NF-кB and NLRP3-related proteins.
    Cloxacillin sodium monohydrate (Standard)
  • HY-P5700
    SAAP Fraction 3
    		Inhibitor
    SAAP Fraction 3 is an antimicrobial peptide. SAAP Fraction 3 is active against P. haemolytica in Zn-saline buffer.
    SAAP Fraction 3
  • HY-N4145
    Procyanidin A3
    		Inhibitor
    Procyanidin A3 (Cinnamtannin A3; Cinnamtannin II) is a sub class of Proanthocyanidins (HY-N0794). Proanthocyanidin are a class of polyphenolic that are widely distributed in higher plants, consisted of an electrophilic flavanyl unit. Proanthocyanidin can be used as antioxidant and anti-cancer agent. Proanthocyanidin also exhibit anti-inflammatory, cardioprotective, antibacterial and antifungal properties, which can be used in the treatment of chronic venous insufficiency, capillary fragility, sunburn and retinopathy.
    Procyanidin A3
  • HY-168881
    Antibacterial agent 262
    		Inhibitor
    Antibacterial agent 262 (compound A23) is a potent antibacterial agent. Antibacterial agent 262 inhibits Xanthomonas oryzae pv oryzae activity. Antibacterial agent 262 inhibits the formation of Xanthomonas oryzae pv oryzae biofilms, disrupting the integrity of bacterial cell membranes.
    Antibacterial agent 262
  • HY-B0441R
    Tobramycin (Standard)
    		Inhibitor
    Tobramycin (Standard) is the analytical standard of Tobramycin. This product is intended for research and analytical applications. Tobramycin (Nebramycin Factor 6) is a parenterally administered, broad spectrum aminoglycoside antibiotic that is widely used in the treatment of moderate to severe bacterial infections due to sensitive organisms.Tobramycin can be used to pneumonia research caused by Pseudomonas aeruginosa.
    Tobramycin (Standard)
  • HY-131054
    Cinerubin B
    		Inhibitor
    Cinerubin B, a glycosylated anthracycline antibiotic, is an anticancer agent from Streptomyces sp. SPB74.
    Cinerubin B
  • HY-N3912
    Furomollugin
    		Inhibitor
    Furomollugin is a natural product with antioxidant and antibacterial activities, can be isolated from Rubia cordifolia. Furomollugin lacks potent anti-tyrosinase activity, but also exhibits significant anticancer property.
    Furomollugin
  • HY-147871
    Antimycobacterial agent-3
    		Inhibitor
    Antimycobacterial agent-3 (Compound 1h) is an antimycobacterial agent against both agent-sensitive MTB strain H37Rv and drug-resistant clinical isolates (MIC: < 0.029–0.110 μM). Antimycobacterial agent-3 shows low cell cytotoxicity.
    Antimycobacterial agent-3
  • HY-15390
    Thiambutosine
    		Inhibitor 99.33%
    Thiambutosine is an inhibitor of Mycobacterium leprae with low oral activity. In animal experiments, Thiambutosine can inhibit leprosy infection by intramuscular injection.
    Thiambutosine
  • HY-176144
    Antibacterial agent 278
    		Inhibitor
    Antibacterial agent 278 (compound B1) is an antibacterial agent. Antibacterial agent 278 exhibites potent activity against Gram-positive bacteria.
    Antibacterial agent 278
  • HY-N10259
    Norfunalenone
    		Inhibitor
    Norfunalenone exhibits weak cytotoxic activity in mouse myeloma NS-1 cell line (ATCC TIB-18) with an IC50 of 70 μM. Norfunalenone also exhibits weak antibacterial activity against B. subtilis (MIC=100 μg/mL; IC50=265 μM).
    Norfunalenone
  • HY-115127S
    3-Methylanisole-d3
    		Inhibitor
    3-Methylanisole-d3 (m-Methoxytoluene-d3; m-MetHYlanisole-d3) is the deuterium labeled 3-Methylanisole (HY-115127). Methylanisole is a volatile metabolite produced by Penicillium strains growing on barley. 3-Methylanisole serves as a precursor for the biotechnological production of vanillin.
    3-Methylanisole-d<sub>3</sub>
  • HY-P5640
    Tritrpticin
    		Inhibitor
    Tritrpticin is a porcine-derived antimicrobial peptide with properties such as membrane disruption and hemolysis. Tritrpticin disrupts the cell membranes of bacteria, fungi and Jurkat T cell leukemia cells and induces their death. Tritrpticin also enhances the efficacy of Metronidazole (HY-B0318) against *Trichomonas vaginalis*, reduces plasma endotoxin and inflammatory cytokine levels, restricts bacterial growth in blood and visceral tissues, decreases the mortality rate of septic shock in rats and enhances the therapeutic effect of ertapenem. Tritrpticin exhibits selective cytotoxicity against Jurkat T cell leukemia cells, while showing low toxicity to normal peripheral blood mononuclear cells and red blood cells, and can serve as a template for antimicrobial peptide design. Tritrpticin can be applied to research related to bacterial infections, fungal infections, trichomoniasis, septic shock and leukemia.
    Tritrpticin
  • HY-B1148B
    Furaltadone L-tartrate
    		Inhibitor
    Furaltadone L-tartrate (Altafur L-tartrate), a nitrofuran agent, has the potential for the study in infections of chickens with salmonella enteritidis. Furaltadone is inhibitory and bactericidal in vitro for staphylococci .
    Furaltadone L-tartrate
Cat. No. Product Name / Synonyms Application Reactivity