Thiambutosine
Based on 1 Customer Validation
Thiambutosine is an inhibitor of Mycobacterium leprae with low oral activity. In animal experiments, Thiambutosine can inhibit leprosy infection by intramuscular injection.
For research use only. We do not sell to patients.
- Purity: 99.33%
- CAS No.: 500-89-0
- Formula: C19H25N3OS
- Molecular Weight:343.49
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Storage:
4°C, protect from light
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
Thiambutosine has antimycobacterial activities with an EC50 of 11 μg/mL for L. m. amazonensis[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 500-89-0
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Appearance Solid
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Molecular Weight 343.49
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Formula C19H25N3OS
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Color White to off-white
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SMILES
S=C(NC1=CC=C(N(C)C)C=C1)NC2=CC=C(OCCCC)C=C2
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Synonyms
CIBA-1906
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
4°C, protect from light
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
Solvent & Solubility
DMSO : 125 mg/mL (363.91 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (267 KB)
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SDS (393 KB)
- English - EN (393 KB)
- Français - FR (393 KB)
- Deutsch - DE (393 KB)
- Norwegian - NO (393 KB)
- Español - ES (393 KB)
- Swedish - SV (393 KB)
- Italian - IT (393 KB)
- Portuguese - PT (393 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 2.9113 mL | 14.5565 mL | 29.1129 mL | 72.7823 mL |
| 5 mM | 0.5823 mL | 2.9113 mL | 5.8226 mL | 14.5565 mL | |
| 10 mM | 0.2911 mL | 1.4556 mL | 2.9113 mL | 7.2782 mL | |
| 15 mM | 0.1941 mL | 0.9704 mL | 1.9409 mL | 4.8522 mL | |
| 20 mM | 0.1456 mL | 0.7278 mL | 1.4556 mL | 3.6391 mL | |
| 25 mM | 0.1165 mL | 0.5823 mL | 1.1645 mL | 2.9113 mL | |
| 30 mM | 0.0970 mL | 0.4852 mL | 0.9704 mL | 2.4261 mL | |
| 40 mM | 0.0728 mL | 0.3639 mL | 0.7278 mL | 1.8196 mL | |
| 50 mM | 0.0582 mL | 0.2911 mL | 0.5823 mL | 1.4556 mL | |
| 60 mM | 0.0485 mL | 0.2426 mL | 0.4852 mL | 1.2130 mL | |
| 80 mM | 0.0364 mL | 0.1820 mL | 0.3639 mL | 0.9098 mL | |
| 100 mM | 0.0291 mL | 0.1456 mL | 0.2911 mL | 0.7278 mL |
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