1. Anti-infection
  2. Bacterial
  3. Thiambutosine

Thiambutosine  (Synonyms: CIBA-1906)

Cat. No.: HY-15390 Purity: 99.33%
COA Handling Instructions

Thiambutosine is an inhibitor of Mycobacterium leprae with low oral activity. In animal experiments, Thiambutosine can inhibit leprosy infection by intramuscular injection.

For research use only. We do not sell to patients.

Thiambutosine Chemical Structure

Thiambutosine Chemical Structure

CAS No. : 500-89-0

Size Price Stock Quantity
5 mg USD 70 In-stock
10 mg USD 115 In-stock
25 mg USD 200 In-stock
50 mg   Get quote  
100 mg   Get quote  

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This product is a controlled substance and not for sale in your territory.

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Based on 1 publication(s) in Google Scholar

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Description

Thiambutosine is an inhibitor of Mycobacterium leprae with low oral activity. In animal experiments, Thiambutosine can inhibit leprosy infection by intramuscular injection[1][2].

Molecular Weight

343.49

Formula

C19H25N3OS

CAS No.
Unlabeled CAS

Appearance

Solid

Color

White to off-white

SMILES

S=C(NC1=CC=C(N(C)C)C=C1)NC2=CC=C(OCCCC)C=C2

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

4°C, protect from light

*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)

Solvent & Solubility
In Vitro: 

DMSO : 125 mg/mL (363.91 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.9113 mL 14.5565 mL 29.1129 mL
5 mM 0.5823 mL 2.9113 mL 5.8226 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 2.9113 mL 14.5565 mL 29.1129 mL 72.7823 mL
5 mM 0.5823 mL 2.9113 mL 5.8226 mL 14.5565 mL
10 mM 0.2911 mL 1.4556 mL 2.9113 mL 7.2782 mL
15 mM 0.1941 mL 0.9704 mL 1.9409 mL 4.8522 mL
20 mM 0.1456 mL 0.7278 mL 1.4556 mL 3.6391 mL
25 mM 0.1165 mL 0.5823 mL 1.1645 mL 2.9113 mL
30 mM 0.0970 mL 0.4852 mL 0.9704 mL 2.4261 mL
40 mM 0.0728 mL 0.3639 mL 0.7278 mL 1.8196 mL
50 mM 0.0582 mL 0.2911 mL 0.5823 mL 1.4556 mL
60 mM 0.0485 mL 0.2426 mL 0.4852 mL 1.2130 mL
80 mM 0.0364 mL 0.1820 mL 0.3639 mL 0.9098 mL
100 mM 0.0291 mL 0.1456 mL 0.2911 mL 0.7278 mL
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Thiambutosine Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Product Name:
Thiambutosine
Cat. No.:
HY-15390
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