2. Signaling Pathways
  3. Anti-infection
  4. Bacterial

Bacterial

Bacterial

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Anything that destroys bacteria or suppresses their growth or their ability to reproduce. Heat, chemicals such as chlorine, and antibiotic drugs all have antibacterial properties. Many antibacterial products for cleaning and handwashing are sold today. Such products do not reduce the risk for symptoms of viral infectious diseases in otherwise healthy persons. This does not preclude the potential contribution of antibacterial products to reducing symptoms of bacterial diseases in the home.

Cat. No. Product Name Effect Purity Chemical Structure
  • HY-N14378
    Parimycin
    		Inhibitor
    Parimycin has activity against Gram-positive bacteria, negative bacteria and tumors, and no effect on fungal. Parimycin can inhibit tumor cells including GXF 251L, H640, LXFA 629L, MCF-7, MEXF 514L with IC70s of 0.9-6.7 μg/mL.
    Parimycin
  • HY-129252
    Prothracarcin
    		Inhibitor
    Prothracarcin is an antibiotic with antitumor activity that exerts its tumor cell toxicity by covalently binding to the C-2 amino group of guanine residues in the minor groove of DNA. Prothracarcin also shows antibacterial activity against Gram-positive bacteria and some Gram-negative bacteria such as Escherichia coli.
    Prothracarcin
  • HY-N4136R
    Lonicerin (Standard)
    		Inhibitor
    Lonicerin (Standard) (Veronicastroside (Standard)) is the analytical standard of Lonicerin (HY-N4136). This product is intended for research and analytical applications. Lonicerin is a flavonoid with multiple biological activities. Lonicerin inhibits xanthine oxidase with an IC50 of 37.4 µg/mL. Lonicerin inhibits alginate secretion protein (AlgE). Lonicerin inhibits P. aeruginosa and C. albicans. Lonicerin has anti-inflammatory, anti-arthritic, antioxidant, antifungal, anti-bacterial, and neuroprotective properties.
    Lonicerin (Standard)
  • HY-178952
    Anti-infective agent 12
    		Inhibitor
    Anti-infective agent 12 (Compound A09) is a competitive inhibitor of type I signal peptidease (SPase I), with an IC50 of 4.475 μM and a Kd of 16.3 μM. Anti-infective agent 12 has the ability to disrupt bacterial membranes and remove biofilms. Anti-infective agent 12 exhibits potent bactericidal activity against Gram-positive bacteria, with MIC values of 4, 4, 8, and 8 μg/mL for Staphylococcus aureus, Enterococcus faecalis, Enterococcus faecium, and Streptococcus suis, respectively. Anti-infective agent 12 remains effective against multi-drug resistant strains, but has weaker activity against Gram-negative bacteria (such as Escherichia coli and Salmonella), with MIC values > 64 μg/mL. Anti-infective agent 12 has low hemolytic activity and shows significant efficacy in mouse skin infection models.
    Anti-infective agent 12
  • HY-180808
    Antibacterial agent 313
    		Inhibitor
    Antibacterial agent 313 (Compound 20) is a broad-spectrum antibacterial agent. Antibacterial agent 313 can be used for research of bacterial infection.
    Antibacterial agent 313
  • HY-N14433
    Fumigatin
    		Inhibitor
    Fumigatin has anti-Gram-positive bacteria, negative bacteria (weak) and vibrio cholerae activities.
    Fumigatin
  • HY-N14860
    Milbemycin β3
    		Inhibitor
    Milbemycin β3 is a macrolide antibiotic. Milbemycin β3 has insecticidal effects on agricultural harmful insects, pans, larvae, etc.
    Milbemycin β3
  • HY-N5169
    Argimicin C
    		Inhibitor
    Argimicin C is an antibiotic that can be isolated from Sphingomonas sp.. Argimicin C exhibits algicidal activity against a variety of toxic cyanobacteria with MIC of low micromolar levels.
    Argimicin C
  • HY-N14344
    Manumycin G
    		Inhibitor
    Manumycin G has anti-Gram-positive bacteria and Escherichia coli effects, but the effect is very weak against other anti-Gram-negative bacteria, and has no effect on fungi. Manumycin G inhibits RAS Faraday base transfer and has weak cytotoxic activity against human cloned cancer cell lines HCT-116 (IC50 is 15.6 μg/mL).
    Manumycin G
  • HY-B0501R
    Danofloxacin mesylate (Standard)
    		Inhibitor
    Danofloxacin mesylate (Standard) is the analytical standard of Danofloxacin mesylate. This product is intended for research and analytical applications. Danofloxacin mesylate (CP 76136-27) is a fluoroquinolone used as a veterinary drug. Danofloxacin mesylate has a broad spectrum of bactericidal activity, mainly inhibiting the DNA cycloenzyme of the bacteria. In addition, Danofloxacin mesylate is a substrate for ATP-dependent efflux transporters (P-gp and MRP2).
    Danofloxacin mesylate (Standard)
  • HY-165460
    AM-112
    		Inhibitor
    AM-112 is a β-lactamase (β-lactamase) inhibitor and antibacterial agent, with IC50 values ranging from 0.0002 μg/mL to 0.67 μg/mL against class A, C, and D β-lactamase. By inhibiting PBP2, the penicillin-binding protein of E. coli, and protecting Ceftazidime (HY-B0593) from enzymatic hydrolysis, AM-112 significantly enhances the antibacterial efficacy of Ceftazidime against Gram-negative bacteria, enterococci, and staphylococci. AM-112 exhibits favorable pharmacokinetic properties and acid-base stability. AM-112 can be used for the research of bacterial infections.
    AM-112
  • HY-158193
    N-Decanoyl cyclopentylamide
    		Inhibitor
    N-Decanoyl cyclopentylamide (C10-CPA) is a potent inhibitor of quorum sensing in Pseudomonas aeruginosa. N-Decanoyl cyclopentylamide interferes with expression of Pseudomonas aeruginosa virulence factors regulated by the las and rhl quorum-sensing systems. N-Decanoyl cyclopentylamide inhibits production of elastase, pyocyanin, and rhamnolipid and biofilm formation.
    N-Decanoyl cyclopentylamide
  • HY-17574R
    Thio-TEPA (Standard)
    		Inhibitor
    Thio-TEPA (Standard) is the analytical standard of Thio-TEPA. This product is intended for research and analytical applications. Thio-TEPA is a DNA alkylating agent, with antitumor activity.
    Thio-TEPA (Standard)
  • HY-156074
    Erythromycin propionate
    		Inhibitor
    Erythromycin propionate, erythromycin (HY-B0220) derivative, is a macrolide antibiotic used in the treatment of a wide variety of bacterial infections. Erythromycin propionate causes several cases of liver injury which mostly include cholestatic hepatitis. Erythromycin propionate toxicity is related to its inhibitory effect on bile acid transport.
    Erythromycin propionate
  • HY-176246
    Antitubercular agent-52
    		Inhibitor
    Antitubercular agent-52 (Compound 7k) is an antitubercular agent targeting Mycobacterium tuberculosis (Mtb). Antitubercular agent-52 selectively inhibits the cytochrome bcc (cyt-bcc) electron transport chain of Mtb and also acts on cytochrome bd (cyt-bd). Antitubercular agent-52 blocks electron transfer and ATP production by interfering with the key energy metabolism pathway of Mtb. Antitubercular agent-52 is promising for research of tuberculosis.
    Antitubercular agent-52
  • HY-116034
    Arasertaconazole
    		Inhibitor
    Arasertaconazole is a potent 14α-lanosterol demethylase inhibitor. Arasertaconazole has antifungal and antibacterial activity.
    Arasertaconazole
  • HY-N14889
    Ophiobolin D
    		Inhibitor
    Ophiobolin D is a terpenoid antibiotic found in Cochliobulus miyabeanus and has four components A, B, C and D. A, B, C have anti-Gram-positive bacteria, mycobacteria and fungi, and have a strong inhibitory effect on some plant pathogens. D has a weak inhibitory effect on Staphylococcus aureus.
    Ophiobolin D
  • HY-W799435
    Tosufloxacin hydrate
    		Inhibitor
    Tosufloxacin (A-61827) tosylate is an orally active fluoroquinolone antibiotic. Tosufloxacin tosylate shows a broad spectrum of antibacterial activity against gram-positive and gram-negative bacteria.
    Tosufloxacin hydrate
  • HY-Y1718R
    Tridecanoic acid (Standard)
    		Inhibitor
    Tridecanoic acid (Standard) is the analytical standard of Tridecanoic acid. This product is intended for research and analytical applications. Tridecanoic acid (N-Tridecanoic acid), a 13-carbon medium-chain saturated fatty acid, can serve as an antipersister and antibiofilm agent that may be applied to research bacterial infections. Tridecanoic acid inhibits Escherichia coli persistence and biofilm formation.
    Tridecanoic acid (Standard)
  • HY-181713
    Antibiofilm agent-19
    		Inhibitor
    Antibiofilm agent-19 is an antibiofilm agent with iron-chelating activity. Antibiofilm agent-19 potently inhibits biofilm formation by wild-type PAO1 and the hyper-biofilm mutant strain PAO1-ΔwspF. Antibiofilm agent-19 promotes the formation of c-di-GMP G-quadruplexes and disrupts iron acquisition systems. It can be used in studies on antibacterial adjuvants.
    Antibiofilm agent-19
Cat. No. Product Name / Synonyms Application Reactivity