Ophiobolin D
Ophiobolin D is a terpenoid antibiotic found in Cochliobulus miyabeanus and has four components A, B, C and D. A, B, C have anti-Gram-positive bacteria, mycobacteria and fungi, and have a strong inhibitory effect on some plant pathogens. D has a weak inhibitory effect on Staphylococcus aureus.
For research use only. We do not sell to patients.
- CAS No.: 24436-08-6
- Formula: C25H36O4
- Molecular Weight:400.55
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
All Antibiotic Isoforms
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Biological Activity
Description
Chemical Information
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CAS No. 24436-08-6
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Molecular Weight 400.55
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Formula C25H36O4
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SMILES
C[C@@]12[C@](C[C@@H](/C(C(O)=O)=C3[C@](C(C)=CC\3=O)([H])C2)O)([H])[C@@](CC1)([H])[C@@H](C)CC/C=C(C)\C
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Structure Classification
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Initial Source
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Protocols
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Gram Staining of Tissue Sections
Gram staining of tissue sections is a histochemical technique used to differentiate Gram-positive and Gram-negative bacteria within histological specimens based on differences in bacterial cell wall structure and dye retention, adapted from classical bacteriological Gram staining into tissue-compatible “histological Gram stain” variants. In tissue applications, modifications of the Brown-Hopps and Brown-Brenn methods are commonly used to improve differentiation of microorganisms embedded within host connective tissue and to reduce overstaining or loss of Gram-negative signal, which are known limitations of earlier approaches. The principle relies on crystal violet-iodine complex retention in Gram-positive organisms and subsequent decolorization and counterstaining steps that allow contrast visualization of Gram-negative organisms against tissue background.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)