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Cat. No.: HY-158193

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N-Decanoyl cyclopentylamide

(Synonyms: C10-CPA)

N-Decanoyl cyclopentylamide (C10-CPA) is a potent inhibitor of quorum sensing in Pseudomonas aeruginosa. N-Decanoyl cyclopentylamide interferes with expression of Pseudomonas aeruginosa virulence factors regulated by the las and rhl quorum-sensing systems. N-Decanoyl cyclopentylamide inhibits production of elastase, pyocyanin, and rhamnolipid and biofilm formation.

For research use only. We do not sell to patients.

CAS No.: 540796-75-6
Formula: C₁₅H₂₉NO
Molecular Weight:239.40

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Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (262 KB)

N-Decanoyl cyclopentylamide Chemical Structure

CAS No.: 540796-75-6

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Biological Activity

Description

In Vitro

N-Decanoyl cyclopentylamide (C10-CPA) inhibits quorum sensing in Pseudomonas aeruginosa, and its concentrations required for half-maximal inhibition for lasB-lacZ and rhlA-lacZ expression are 80 μM and 90 μM, respectively^[1].
N-Decanoyl cyclopentylamide also inhibits production of virulence factors, including elastase, pyocyanin, and rhamnolipid, and biofilm formation without affecting growth of Pseudomonas aeruginosa PAO1^[1].
N-Decanoyl cyclopentylamide interferes with the las and rhl quorum-sensing systems via inhibiting interaction between their response regulators (LasR and RhlR) and autoinducers^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Chemical Information

CAS No. 540796-75-6
Molecular Weight 239.40
Formula C₁₅H₂₉NO
SMILES

O=C(CCCCCCCCC)NC1CCCC1
Synonyms

C10-CPA
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Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (262 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Takenori Ishida, et al. Inhibition of quorum sensing in Pseudomonas aeruginosa by N-acyl cyclopentylamides. Appl Environ Microbiol. 2007 May;73(10):3183-8. [Content Brief]

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How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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N-Decanoyl cyclopentylamide

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N-Decanoyl cyclopentylamide Related Classifications

HY-158193 Related Classifications