1. Signaling Pathways
  2. Anti-infection
  3. Bacterial

Bacterial

Anything that destroys bacteria or suppresses their growth or their ability to reproduce. Heat, chemicals such as chlorine, and antibiotic drugs all have antibacterial properties. Many antibacterial products for cleaning and handwashing are sold today. Such products do not reduce the risk for symptoms of viral infectious diseases in otherwise healthy persons. This does not preclude the potential contribution of antibacterial products to reducing symptoms of bacterial diseases in the home.

Cat. No. Product Name Effect Purity Chemical Structure
  • HY-14879R
    Avibactam free acid (Standard)
    Inhibitor
    Avibactam (free acid) (Standard) is the analytical standard of Avibactam (free acid). This product is intended for research and analytical applications. Avibactam (NXL-104) free acid is a covalent and reversible non-β-lactam β-lactamase inhibitor which inhibits β-lactamase TEM-1 and CTX-M-15 with IC50s of 8 nM and 5 nM, respectively[1].
    Avibactam free acid (Standard)
  • HY-N14041
    Arizonin A2
    Inhibitor
    Arizonin A2 is a microbial metabolite with anti-Gram-positive bacterial activities.
    Arizonin A2
  • HY-106572
    Cefbuperazone
    Inhibitor
    Cefbuperazone belongs to the cephalomycin-type compound.
    Cefbuperazone
  • HY-U00092A
    BAY-Y 3118 hydrochloride
    Inhibitor
    BAY-Y 3118 hydrochloride is a quinolone antibacterial agent. BAY-Y 3118 hydrochloride has a broad antibacterial spectrum in vitro. BAY-Y 3118 hydrochloride exhibits high activity against gram-positive cocci and anaerobes. BAY-Y 3118 hydrochloride shows moderate activity against Enterobacteriaceae and Pseudomonas aeruginosa. BAY-Y 3118 hydrochloride can be used in the research of infectious diseases.
    BAY-Y 3118 hydrochloride
  • HY-N7515A
    (E)-Pinocembrin chalcone
    Inhibitor
    (E)-Pinocembrin chalcone is an antibacterial compound that can be isolated from Helichrysum trilineatum.
    (E)-Pinocembrin chalcone
  • HY-N14404
    Fosfadecin
    Inhibitor
    Fosfadecin has a weak antibacterial activity.
    Fosfadecin
  • HY-130046R
    16-Epiestriol (Standard)
    Inhibitor
    16-Epiestriol (Standard) is the analytical standard of 16-Epiestriol (HY-130046). This product is intended for research and analytical applications. 16-Epiestriol (16-epi-Estriol; 16β,17β-Estriol) is a natural stereoisomer of estriol and an anti-inflammatory agent that targets UGT. The Ki values of 16-Epiestriol against human UGT1A10 and UGT2B7 are 98.1 μM and 162 μM, respectively. As a glucuronidation substrate, 16-Epiestriol can be modified at the 3-OH, 16-OH and 17-OH sites by various UGT enzymes; in liver microsomes, the modification mainly occurs at the 16-OH and 17-OH sites, while reactions take place at all three sites in intestinal microsomes. 16-Epiestriol acts on the phase II inflammatory process by blocking edema mediated by prostaglandins and leukocyte infiltration. It lacks glycogenic activity or any effect on blood glucose levels, and serves as an important candidate molecule in the research of inflammatory diseases.
    16-Epiestriol (Standard)
  • HY-D0896AR
    ANS ammonium (Standard)
    Inhibitor
    ANS (ammonium) (Standard) is the analytical standard of ANS (ammonium). This product is intended for research and analytical applications. ANS ammonium is a potent antibacterial agent and a textile dye. ANS ammonium can be used as fluorescence probe. ANS ammonium blocks the binding of triiodothyronine to thyroxine binding globulin in radioimmunoassay of triiodothyronine.
    ANS ammonium (Standard)
  • HY-N14172
    Epicorazine B
    Inhibitor
    Epicorazine B has activity against Gram-positive bacteria, including methicillin-resistant Staphylococcus aureus (MRSA) and vancomycin resistant enterococcus (VRE), MICs of 12.5-25 μg/mL. Epicorazine B also has effect on Candida albicans with a MIC of 25 μg/mL.
    Epicorazine B
  • HY-N7114AR
    Chloramphenicol succinate sodium (Standard)
    Inhibitor
    Chloramphenicol succinate sodium (Standard) is the analytical standard of Chloramphenicol succinate sodium. This product is intended for research and analytical applications. Chloramphenicol succinate sodium is a prodrug of Chloramphenicol (HY-B0239), acting as a P2Y14R inhibitor with an IC50 of 1.585 nM. Chloramphenicol succinate sodium serves as a competitive substrate and inhibitor of succinate dehydrogenase (SDH), which may account for its toxicity. Chloramphenicol succinate sodium exerts a significant inhibitory effect on colitis. Chloramphenicol succinate sodium can be used in research related to myelosuppression, gray baby syndrome, aplastic anemia, bacterial meningitis and inflammatory bowel disease.
    Chloramphenicol succinate sodium (Standard)
  • HY-B0947R
    Sulfanitran (Standard)
    Inhibitor
    Sulfanitran (Standard) is the analytical standard of Sulfanitran. This product is intended for research and analytical applications. Sulfanitran is an antibacterial and anticoccidial agent used in poultry feeds. Sulfanitran also is a multidrug resistance protein 2 (MRP2) stimulator that can increase the affinity of MRP2 for estradiol-17-β-D-glucuronide (E217βG).
    Sulfanitran (Standard)
  • HY-179611
    LP-03
    Inhibitor
    LP-03 is an antibacterial agent with selective activity against Methicillin-resistant Staphylococcus aureus (MRSA). Its minimum inhibitory concentration (MIC) is 6.2 μM. LP-03 has an inhibitory effect on biofilm formation, but it is unable to effectively remove the formed biofilms. LP-03 can enhance membrane permeability, disrupt the membrane structure of MRSA cells, and does not cause significant membrane depolarization. LP-03 has no hemolytic toxicity and shows low mammalian cell toxicity. It can be used for research on MRSA infections.
    LP-03
  • HY-125163
    MM 47755
    Inhibitor
    MM 47755 (8-O-Methyltetrangomycin; 6-Deoxy-8-O-methylrabelomycin) is an antibiotic with antibacterial activity. MM 47755 can be isolated from Streptomyces.
    MM 47755
  • HY-N14306
    Aspersitin
    Inhibitor
    Aspersitin is a metabolite of Aspergillus parasiticus with antibacterial activity.
    Aspersitin
  • HY-B0458R
    Cefprozil monohydrate (Standard)
    Inhibitor
    Cefprozil monohydrate (Standard) is the analytical standard of Cefprozil monohydrate (HY-B0458). This product is intended for research and analytical applications. Cefprozil monohydrate is a second-generation cephalosporin type antibiotic. Cefprozil monohydrate exhibits broad-spectrum antibacterial activity, and is orally active. Cefprozil monohydrate can be used for the study of pharyngitis, tonsillitis, otitis media, and uncomplicated skin infections.
    Cefprozil monohydrate (Standard)
  • HY-N16657
    Fusaricidin B
    Inhibitor
    Fusaricidin B (LI-F 04b) is one of the components of a lipopeptide biosurfactant extracted from the marine bacterium Paenibacillus polymyxa. Fusaricidin B can significantly inhibit the formation of multiple single species biofilms, including Gram positive and Gram negative bacteria. Fusaricidin B also has inhibitory effects on complex biofilms and can effectively destroy mature biofilms that have already formed. Fusaricidin B can be used for research on bacterial infections.
    Fusaricidin B
  • HY-181810
    EG36
    Inhibitor
    EG36 is a selective E. coli DnaK inhibitor that inhibits DnaK ATPase activity at a concentration of 100 μM. EG36 directly binds to the nucleotide-binding domain (NBD) of E. coli DnaK by disrupting the DnaK-DnaJ interaction. EG36 can be used for research on bacterial infectious diseases.
    EG36
  • HY-N14260
    Hypelcin A-II
    Inhibitor
    Hypelcin A-II has anti-Gram-negative bacterial and fungal activity.
    Hypelcin A-II
  • HY-168861
    NDM-1 inhibitor-8
    Inhibitor
    NDM-1 inhibitor-8 (Compound 18b) is the covalent inhibitor for new delhi metallo-β-lactamase-1 (NDM-1) with an IC50 of 7.03 μM. NDM-1 inhibitor-8 inhibits the drug resistant strains, exhibits synergistic antibacterial effect with the use of Meropenem (HY-13678). NDM-1 inhibitor-8 exhibits anti-infectious activity in mouse models.
    NDM-1 inhibitor-8
  • HY-N14422
    Collismycin B
    Inhibitor
    Collismycin B is a potent dexamethasone-glucocorticoid receptor inhibitor with an IC50 value of 10 µM. Collismycin B shows antimicrobial activity. Collismycin B shows cytotoxicity.
    Collismycin B
Cat. No. Product Name / Synonyms Application Reactivity