2. Anti-infection
  3. Bacterial
  4. LP-03

LP-03 is an antibacterial agent with selective activity against Methicillin-resistant Staphylococcus aureus (MRSA). Its minimum inhibitory concentration (MIC) is 6.2 μM. LP-03 has an inhibitory effect on biofilm formation, but it is unable to effectively remove the formed biofilms. LP-03 can enhance membrane permeability, disrupt the membrane structure of MRSA cells, and does not cause significant membrane depolarization. LP-03 has no hemolytic toxicity and shows low mammalian cell toxicity. It can be used for research on MRSA infections.

For research use only. We do not sell to patients.

LP-03

LP-03 Chemical Structure

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LP-03 Related Antibodies

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Description

LP-03 is an antibacterial agent with selective activity against Methicillin-resistant Staphylococcus aureus (MRSA). Its minimum inhibitory concentration (MIC) is 6.2 μM. LP-03 has an inhibitory effect on biofilm formation, but it is unable to effectively remove the formed biofilms. LP-03 can enhance membrane permeability, disrupt the membrane structure of MRSA cells, and does not cause significant membrane depolarization. LP-03 has no hemolytic toxicity and shows low mammalian cell toxicity. It can be used for research on MRSA infections[1].

Molecular Weight

509.43

Formula

C27H29BrN2O3
SMILES

[H][C@]12C(CC[C@]1(C(CC[C@@]3([C@@]2(OC([C@@]34[C@@]5(C(NC6=C5C=C(C=C6)Br)=O)N7CCC[C@H]7C4)=O)[H])[H])=C)[H])=C
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Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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LP-03 Related Classifications

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Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

LP-03LP03LP 03BacterialDehydrocostuslactone1,3-dipolar cycloadditionDispiro-oxindolesAntimicrobial agentsMRSA inhibitionStructure-activity relationshipInhibitorinhibitorinhibit

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