2. Signaling Pathways
  3. Anti-infection
  4. Bacterial

Bacterial

Bacterial

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Anything that destroys bacteria or suppresses their growth or their ability to reproduce. Heat, chemicals such as chlorine, and antibiotic drugs all have antibacterial properties. Many antibacterial products for cleaning and handwashing are sold today. Such products do not reduce the risk for symptoms of viral infectious diseases in otherwise healthy persons. This does not preclude the potential contribution of antibacterial products to reducing symptoms of bacterial diseases in the home.

Cat. No. Product Name Effect Purity Chemical Structure
  • HY-139764
    Antibacterial agent 47
    		Inhibitor
    Antibacterial agent 47, an antibacterial agent, significantly lowers MIC value of antibacterial agent Ceftazidime.
    Antibacterial agent 47
  • HY-B2176S8
    ATP-13C10,15N5,d14 (dilithium)
    ATP-13C10,15N5,d14 (Adenosine 5'-triphosphate-13C10,15N5,d14) dilithium is the 13C-, 15N- and deuterium labeled ATP dilithium. ATP (Adenosine 5'-triphosphate) is a central component of energy storage and metabolism in vivo. ATP provides the metabolic energy to drive metabolic pumps and serves as a coenzyme in cells. ATP is an important endogenous signaling molecule in immunity and inflammation. ATP can activate the NLRP3 inflammasome and induce IL-1β and chemokines secretion. ATP has anti-bacterial infection effects and can protect mice against bacterial infection in mice.
    ATP-<sup>13</sup>C<sub>10</sub>,<sup>15</sup>N<sub>5</sub>,d<sub>14</sub> (dilithium)
  • HY-145881
    Elongation factor P-IN-2
    Elongation factor P-IN-2 is a potent inhibitor elongation factor P (EFP). Elongation factor P-IN-2 is a β-lysine derivative compound. Elongation factor P-IN-2 affects the proliferation rates of E. coli.
    Elongation factor P-IN-2
  • HY-N8281
    Daldinone A
    		Inhibitor
    Daldinone A (Compound 4) is an antibacterial agent that can be isolated from Nigrospora oryzae. Daldinone A has antimicrobial potential against P. aeruginosa.
    Daldinone A
  • HY-162429
    Antibacterial agent 205
    		Inhibitor
    Antibacterial agent 205 (Compound 10d) is a indolylacryloyl-derived oxacins, which exhibits broad antibacterial spectrum with MIC of 0.25-0.5 μg/mL. Antibacterial agent 205 reduces the exopolysaccharide, eliminates the biofilm, and thus attenuates the drug resistance. Antibacterial agent 205 exhibits antibacterial activity through destory of membrane integrity, accumulation of reactive oxygen species ROS, and inhibition of DNA replication.
    Antibacterial agent 205
  • HY-W083821
    1-[(4-Nitrophenyl)methyl]-1,4-diazepane
    		Inhibitor
    1-[(4-Nitrophenyl) methyl]-1,4-diazepane (1-(4-Nitrobenzyl)-1,4-diazepane) is an anti-biofilm agent. 1-[(4-Nitrophenyl) methyl]-1,4-diazepane reduces biofilm formation in Escherichia coli. 1-[(4-Nitrophenyl) methyl]-1,4-diazepane is used for the research of Escherichia coli biofilm-related infections.
    1-[(4-Nitrophenyl)methyl]-1,4-diazepane
  • HY-B1064R
    Clindamycin phosphate (Standard)
    		Inhibitor
    Clindamycin phosphate (Standard) is the analytical standard of Clindamycin phosphate. This product is intended for research and analytical applications. Clindamycin phosphate (Clindamycin 2-phosphate) is a broad-spectrum bacteriostatic lincosamide antibiotic. Clindamycin phosphate is the proagent of Clindamycin (HY-B1455) with no antimicrobial activity in vitro but can be rapidly converted in vivo to the active parent agent, Clindamycin, by phosphatase ester hydrolysis. Clindamycin phosphate can be used for researching acne and bacterial vaginosis.
    Clindamycin phosphate (Standard)
  • HY-15025AS
    Sildenafil citrate-d8
    Sildenafil (citrate)-d8 is the deuterium labeled Sildenafil citrate. Sildenafil citrate is a potent phosphodiesterase type 5 (PDE5) inhibitor with IC50 of 5.22 nM.
    Sildenafil citrate-d<sub>8</sub>
  • HY-B1459AS
    Dicloxacillin-13C4
    Dicloxacillin-13C4 is the 13C labeled Dicloxacillin (HY-B1459A). Dicloxacillin is a β-lactam antibiotic of the penicillin family. Dicloxacillin against Gram-positive bacteria. Dicloxacillin is active against β-lactamase-producing organisms such as Staphylococcus aureus.
    Dicloxacillin-<sup>13</sup>C<sub>4</sub>
  • HY-126732
    L-640876
    		Inhibitor
    L-640876 is a broad-spectrum and orally active lactam antimicrobial agent. L-640876 showa MIC90 of 0.125 pg/mL for the E. coli strains, 2 /mg/mL for the S.choleraerai strains and 4 pg/mL for the S. typhinwrium strains.
    L-640876
  • HY-107120
    CB-182804
    		Inhibitor
    CB-182804, Polymyxin B (HY-149179) analogue, is a polypeptide antibiotic. CB-182804 has inhibitory activity against all Gram-negative pathogenic bacteria, including Escherichia coli, Klebsiella pneumoniae, Acinetobacter baumannii, and Pseudomonas aeruginosa with MIC50 values of 2 μg/mL. CB-182804 is mainly used for the research on refractory infections caused by multidrug-resistant (MDR) Gram-negative bacteria.
    CB-182804
  • HY-A0163CR
    trans-Clopenthixol dihydrochloride (Standard)
    		Inhibitor
    trans-Clopenthixol (dihydrochloride) (Standard) is the analytical standard of trans-Clopenthixol (dihydrochloride). This product is intended for research and analytical applications. trans-Clopenthixol ((E)-Clopenthixol) dihydrochloride is an antibiotic agent, without neuroleptic effect. trans-Clopenthixol can be used to inhibit Pseudomonas aeruginosa and Plasmodium falciparum in vitro[1][2].
    trans-Clopenthixol dihydrochloride (Standard)
  • HY-W403633
    Hexahydrohippuric acid
    		Inhibitor 98.44%
    Hexahydrohippuric acid is a metabolite of Shikimate acid in both liver and kidney, under microbial metabolism effect. Hexahydrohippuric acid is made of cyclohexane carboxylic acid and glycinamide, and shows antibacterial activity.
    Hexahydrohippuric acid
  • HY-P10230
    Sublancin
    		Inhibitor
    Sublancin is an antimicrobial peptide, which inhibits DNA replication, transcription and translation, without affecting membrane integrity. Sublancin suppresses glucose uptake for the competition of phosphotransferase system (PTS). Sublancin inhibits B. subtilis strain 168 ΔSPβ with MIC of 0.312 μM.
    Sublancin
  • HY-121333
    Dinactin
    		Inhibitor
    Dinactin, an antibiotic ionophore produced by Streptomyces species, as an effective small molecule targeting Wnt/β-catenin signaling pathway in cancer cells. Dinactin shows marked inhibition of HCT-116 cell growth with an IC50 of 1.1 μM. Dinactin shows anti-proliferative activity against the cancer cells in apoptosis-independent manner. Dinactin is also an effective agent for the research of neuropathic pain.
    Dinactin
  • HY-125461
    Altersolanol A
    		Inhibitor
    Altersolanol A (Stemphylin; NSC 173943) exhibits antimicrobial activities against Bacillus subtilis and Pseudomonas aeruginosa, with MIC of 25-100 μg/mL. Altersolanol A exhibits no phytotoxicity to Taxus (at dose of 4 μg/μL).
    Altersolanol A
  • HY-W588257
    (+)-Thienamycin
    		Inhibitor
    (+)-Thienamycin is a potent broad-spectrum antibacterial and β-lactamase inhibitor that can be from Streptomyces cattleya.
    (+)-Thienamycin
  • HY-B0535AS
    Ethambutol-d4 dihydrochloride
    		Inhibitor
    Ethambutol-d4 dihydrochloride is deuterated labeled Ethambutol dihydrochloride (HY-B0535A). Ethambutol dihydrochloride is an antimycobacterial compound that prevents cell wall formation by inhibiting arabinosyltransferase activity.
    Ethambutol-d<sub>4</sub> dihydrochloride
  • HY-172962
    DNA Gyrase-IN-17
    DNA Gyrase-IN-17 (Compound 5C) is a DNA Gyrase inhibitor. DNA Gyrase-IN-17 exhibits significant antibacterial activity against a variety of Gram-positive and Gram-negative strains (such as Enterococcus faecalis, Escherichia coli, Pseudomonas aeruginosa, etc.), with a MIC value of 62.5 μg/mL. DNA Gyrase-IN-17 interferes with DNA replication by inhibiting bacterial DNA gyrase. DNA Gyrase-IN-17 can be used in the development of antibacterial drugs, especially for the study of drug-resistant strains.
    DNA Gyrase-IN-17
  • HY-138050
    Nyasol
    		Inhibitor
    Nyasol ((-)-Nyasol) is an active compound that has antifungal, antibacterial, antileishmanial, hyaluronidase inhibition activities. Nyasol inhibits LTB4 binding to human neutrophils. Nyasol suppresses neuroinflammatory response through the inhibition of I-κB degradation in LPS (HY-D1056)-stimulated BV-2 microglial cells.
    Nyasol
Cat. No. Product Name / Synonyms Application Reactivity