2. Signaling Pathways
  3. Anti-infection
  4. Bacterial

Bacterial

Bacterial

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Anything that destroys bacteria or suppresses their growth or their ability to reproduce. Heat, chemicals such as chlorine, and antibiotic drugs all have antibacterial properties. Many antibacterial products for cleaning and handwashing are sold today. Such products do not reduce the risk for symptoms of viral infectious diseases in otherwise healthy persons. This does not preclude the potential contribution of antibacterial products to reducing symptoms of bacterial diseases in the home.

Cat. No. Product Name Effect Purity Chemical Structure
  • HY-160669
    Antibacterial agent 198
    		Inhibitor
    Antibacterial agent 198 (Compound 16) is an antibacterial agent against gram positive Staphylococcus aureus and strains of Entercoccus.
    Antibacterial agent 198
  • HY-N7123S1
    Sulfacetamide-13C6
    		Inhibitor
    Sulfacetamide-13C6 (Sulphacetamide13C6) is the 13C6 labeled Sulfacetamide (HY-N7123). Sulfacetamide (Sulphacetamide) is a sulfonamide antibiotic that can be used for the study of ocular infections. Sulfacetamide has antifungal and antibacterial activities.
    Sulfacetamide-<sup>13</sup>C<sub>6</sub>
  • HY-143292
    Antibacterial agent 81
    		Inhibitor
    Antibacterial agent 81 is a DNA transcription inhibitor. Antibacterial agent 81 inhibits S. aureus USA300 and M. smegmatis ATCC14468 with MIC values of 12.5 and 7.8 μM, respectively. Antibacterial agent 81 can be used for the research of infection.
    Antibacterial agent 81
  • HY-W725641
    Tricyclazole-d3
    		Inhibitor
    Tricyclazole-d3 is the deuterium labeled Tricyclazole. Tricyclazole is a pentaketide-derived melanin biosynthesis inhibitor.
    Tricyclazole-d<sub>3</sub>
  • HY-181994
    RNAP-IN-1
    		Inhibitor
    RNAP-IN-1 is a ribonucleic acid polymerase (RNAP) inhibitor, with an IC50 of 0.95 μM against E. coli RNAP. RNAP-IN-1 can be used in studies of bacterial infections.
    RNAP-IN-1
  • HY-B0147S
    Pefloxacin-d5
    		Inhibitor 98.33%
    Pefloxacin-d5 (Pefloxacinium-d5) is the deuterium labeled Pefloxacin (HY-B0147). Pefloxacin (Pefloxacinium) is a broad spectrum antibiotic. Pefloxacin blocks DNA replication by inhibiting DNA gyrase. Pefloxacin inhibits DNA relaxation catalyzed by topoisomerase I with an IC50 of 45 μg/mL. Pefloxacin exhibits antibacterial activity against Escherichia coli, Pseudomonas aeruginosa, and Bacteroides fragilis with MIC90s of 0.12, 4, and 16 mg/L, respectively. Pefloxacin has anti-Plasmodium yoelii infection activity. Pefloxacin increase UVA-induced edema and immunesuppression. Pefloxacin can be used for infection studies.
    Pefloxacin-d<sub>5</sub>
  • HY-N9907
    7,3′-Dihydroxy-8,4′-dimethoxyisoflavone
    		Inhibitor
    7,3′-Dihydroxy-8,4′-dimethoxyisoflavone is an isoflavone Antibacterial agent. 7,3′-Dihydroxy-8,4′-dimethoxyisoflavone is isolated from the stems of S. parviflorus. 7,3′-Dihydroxy-8,4′-dimethoxyisoflavone exhibits weak antibacterial activity against Gram-positive and Gram-negative bacterial strains. 7,3′-Dihydroxy-8,4′-dimethoxyisoflavone can be used in the research of bacterial infections.
    7,3′-Dihydroxy-8,4′-dimethoxyisoflavone
  • HY-147349A
    Pilabactam
    		Inhibitor
    Pilabactam (ANT3310) is a broad-spectrum covalent Serine β-Lactamase inhibitor, with IC50 values ranging from 1 nM to 175 nM (a panel of Serine β-Lactamase). Pilabactam potentiates activity of β-lactam antibiotics against Carbapenem-Resistant Enterobacterales (CRE) and Acinetobacter baumannii (CRAB). Pilabactam can be used in the research of bacterial infection.
    Pilabactam
  • HY-P5678
    Bombinin H4
    		Inhibitor
    Bombinin H4 is an antimicrobial peptide derived from the skin of moth Bombina variegata. The lethal concentrations of Bombinin H4 against Escherichia coli D21 and Staphylococcus aureus Cowan 1 are 4.8 and 3.3 μM, respectively.
    Bombinin H4
  • HY-155504
    Metallo-β-lactamase-IN-11
    		Inhibitor
    Metallo-β-lactamase-IN-11 (compound 5f) is a Metallo-β-lactamases (MBLs) inhibitor, potent against bacterial metallophyllactamase CphA (IC50=45 µM). Metallo-β-lactamase-IN-11 (10 µM) inhibits NDM-1 by 49% and AIM-1 by 61%. Metallo-β-lactamase-IN-11 can be used in the research of inhibiting antibiotic resistance.
    Metallo-β-lactamase-IN-11
  • HY-N14162
    Dihydroabikoviromycin
    		Inhibitor
    Dihydroabikoviromycin, a secondary metabolite of Streptomyces anulatus, is a polyketide synthase inhibitor.
    Dihydroabikoviromycin
  • HY-177540
    ent-Rhizocarpic acid
    		Inhibitor
    ent-Rhizocarpic acid is an enantiomer of Rhizocarpic acid. ent-Rhizocarpic acid has more potent antibacterial and antiparasitic activity against Staphylococcus aureus (ATCC 25923) and Giardiaduodenalis 713 compared to Rhizocarpic acid. ent-Rhizocarpic acid also has a weak but selective antitumor activity against NS-1 cells.
    ent-Rhizocarpic acid
  • HY-P5672
    Maximin 39
    		Inhibitor
    Maximin 39 is an antimicrobial peptide derived from the toad brain. Maximin 39 is active against Staphylococcus aureus and Escherichia coli, with MIC values of 18.8, 37.5 μg/mL, respectively.
    Maximin 39
  • HY-181751
    FabI-IN-1
    		Inhibitor
    FabI-IN-1 is a FabI (enoyl-acyl carrier protein reductase) inhibitor with a Ki of 0.32 μM against E. coli FabI. FabI-IN-1 inhibits exhibits activity against Gram-negative bacteria including Escherichia coli (MIC = 6.25 μM) and Klebsiella pneumoniae. FabI-IN-1 rescues Galleria mellonella larvae from lethal Escherichia coli infection. FabI-IN-1 exerts a synergistic effect with Colistin (HY-113678) against Escherichia coli. FabI-IN-1 can be used for the research of gram-negative bacterial infection.
    FabI-IN-1
  • HY-106597
    Pirlimycin
    		Inhibitor
    Pirlimycin, a lincosamide antibiotic, is active against Gram-positive bacteria. Pirlimycin acts by inhibiting bacterial protein synthesis via binding with the 50S subunit of the ribosome.
    Pirlimycin
  • HY-N18705
    Cinnamomum zeylanicum extract
    Cinnamomum zeylanicum extract is derived from the bark, leaves, and other parts of the Cinnamomum zeylanicum tree. It is rich in bioactive compounds such as cinnamaldehyde, eugenol, and linalool. Cinnamomum zeylanicum extract is widely used due to its anti-inflammatory, antibacterial, and antioxidant properties.
    Cinnamomum zeylanicum extract
  • HY-106959
    Flurithromycin
    		Inhibitor 99.73%
    Flurithromycin ((8S)-8-Fluoroerythromycin A) is an orally active broad spectrum antibiotic. Flurithromycin can be used in the research of bacterial infections.
    Flurithromycin
  • HY-183542
    DprE1-IN-15
    		Inhibitor
    DprE1-IN-15 is a covalent Mycobacterium tuberculosis essential cell wall enzyme DprE1 inhibitor with an IC50 of 0.073 μM. DprE1-IN-15 forms an irreversible covalent adduct with its target enzyme. DprE1-IN-15 shows inhibitory effects against multiple Mycobacterium tuberculosis.
    DprE1-IN-15
  • HY-163042
    HSGN-218
    		Inhibitor
    HSGN-218 is an antibacterial agent with low Caco-2 permeability. HSGN-218 efficiently inhibits the growth of different C. difficile species with MIC values ranging from 0.007 μM to 0.07 μM.
    HSGN-218
  • HY-121076
    Berteroin
    		Inhibitor 99.9%
    Berteroin, a naturally occurring Sulforaphane analog, ia an antimetastatic agent. Berteroin has anti-inflammatory, antitumor and bactericidal effects.
    Berteroin
Cat. No. Product Name / Synonyms Application Reactivity