1. Signaling Pathways
  2. Cell Cycle/DNA Damage
  3. Polo-like Kinase (PLK)
  4. Polo-like Kinase (PLK) Inhibitors

Polo-like Kinase (PLK) Inhibitors

PLK1

PLK2

PLK3

PLK4

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Sorry. There is currently no product that acts on isoform together.

Please try each isoform separately.

Polo-like Kinase (PLK) Inhibitors
Product Name PLK1 PLK2 PLK3 PLK4 Purity
Wortmannin    
PLK3, IC50: 48 nM
  99.85%
BI 2536
PLK1, IC50: 0.83 nM
Plk2/Snk, IC50: 3.5 nM
Plk3/Fnk, IC50: 9 nM
  99.95%
Volasertib
PLK1, IC50: 0.87 nM
PLK2, IC50: 5 nM
PLK3, IC50: 56 nM
  99.55%
Centrinone      
PLK4, Ki: 0.16 nM
PLK4 (G95L), Ki: 68.57 nM
98.57%
Rigosertib sodium
PLK1, IC50: 9 nM
PLK2, IC50: 260 nM
    99.49%
TC-S 7005
PLK1, IC50: 214 nM
PLK2, IC50: 4 nM
PLK3, IC50: 24 nM
  >99.0%
GW843682X
PLK1, IC50: 2.2 nM
 
PLK3, IC50: 9.1 nM
  99.75%
GSK461364
PLK1, Ki: 2.2 nM
      99.82%
CFI-400945 free base      
PLK4, IC50: 2.8 nM
98.45%
CFI-400945 fumarate      
PLK4, IC50: 2.8 nM
99.27%
Centrinone-B      
PLK4, Ki: 0.59 nM
PLK4 (G95L), Ki: 497.53 nM
98.97%
Rigosertib
PLK1, IC50: 9 nM
PLK2, IC50: 260 nM
    98.81%
Poloxin
PLK1 PBD, IC50: 4.8 μM
PLK2 PBD, IC50: 18.7 μM
PLK3 PBD, IC50: 53.9 μM
  96.26%
Ro3280
PLK1, Kd: 0.09 nM
      99.85%
MLN0905
PLK1, IC50: 2 nM
      99.94%
LFM-A13
Plx1, IC50: 10 μM
 
PLK3, IC50: 61 μM
  99.70%
SBE13 Hydrochloride
PLK1, IC50: 200 pM
 
PLK3, IC50: 875 nM
  98.61%
HMN-214
PLK1
      99.25%
SBE13
PLK1, IC50: 200 pM
 
PLK3, IC50: 875 nM
 
Poloxime
PLK1
      >95.0%