2. Signaling Pathways
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  4. Fluorescent Dye

Fluorescent Dye

Fluorescence is a phenomenon of photoluminescence in luminescence. When an atom is irradiated by light, some electrons around the nucleus jump from their original orbitals to higher energy orbitals under the influence of light energy, i.e., from the ground state to the first or second excited single-line state, etc. Due to the instability of the first or second excited singlet state, the electron returns from the excited singlet state to the ground state accompanied by released energy, resulting in fluorescence.

Fluorescent dyes can be covalently bound or physically adsorbed in the structure of the substance. The fluorescence properties allow for the characterization, localization and quantitative analysis of the labeled object. Fluorescent dyes have shown great potential for the detection of proteins, nucleic acids, cells, and immunoassays, attributed to the advantages in non-radioactive contamination, simple experimental operation and easy observation.

Fluorescent dyes have penetrated many fields such as pharmacology, physiology, environmental science, and information science, as well as functional studies of proteins and drug screening.

Cat. No. Product Name Effect Purity Chemical Structure
  • HY-D0497
    C.I. Disperse orange 37
    C.I. Disperse orange 37 is an orange-orange dye commonly used for fiber dyeing.
    C.I. Disperse orange 37
  • HY-D2592
    Cy7.5-PEG1000-DSPE
    Cy7.5-PEG1000-DSPE is a PEG phospholipid with CY7.5 (HY-D0926) dye used in protein/nucelic acid labeling and fluorescence microscopy. Cy7.5-PEG1000-DSPE can self-assemble in aqueous solution to form micelles/lipid bilayer and used to prepare liposomes or nanoparticles for nutrients delivery such as mRNA or DNA vaccine (Ex/Em=770/820 nm).
    Cy7.5-PEG1000-DSPE
  • HY-D0625
    Disperse Red 177
    Disperse Red 177 is a red dye derived from anthraquinone. It is used in plastics, textiles and cosmetics.
    Disperse Red 177
  • HY-D0725
    C.I. Pigment yellow 180
    C.I. Pigment yellow 180 is the most important colorant used to add color or change the color of something and is chemically essentially unaffected by the carrier or medium into which it is incorporated. It can be widely used in textile, medicine, food, cosmetics, plastics, paint, ink, photography and paper industries.
    C.I. Pigment yellow 180
  • HY-D0325
    Direct Black BH sodium
    Direct Black BH sodium is a good dyeing agent for cotton fabrics.
    Direct Black BH sodium
  • HY-175046
    C12 Lissamine-rhodamine galactosylceramide (d18:1/12:0)
    C12 Lissamine-rhodamine galactosylceramide (d18:1/12:0) (Lissamine-rhodamine B-dodecanoyl Galactosylceramide) is a fluorescently labeled version of C12 galactosylceramide.
    C12 Lissamine-rhodamine galactosylceramide (d18:1/12:0)
  • HY-D2622
    Cy3 HA (MW 3000)
    Cy3 HA (MW 3000) is a hyaluronic acid labeled with CY3 (HY-D0822). Cy3 HA (MW 3000) is widely used for cell imaging and in vivo imaging of shallow tissue (Ex/Em = 550/570 nm).
    Cy3 HA (MW 3000)
  • HY-D2121
    Cy3-PEG7-endo-BCN
    Cy3-PEG7-endo-BCN is a dye derivative of Cyanine 3 (Cy3) (HY-D0822) containing 7 PEG units. Cy3-PEG7-endo-BCN contains the lyophilic bidentate macrocyclic ligand BCN, which can further synthesize macrocyclic complexes. In click chemistry, endo-BCN can react with molecules containing azide groups to form stable triazoles in the absence of catalysts.
    Cy3-PEG7-endo-BCN
  • HY-D2757
    5(6)-Carboxyrhodamine 110 NHS ester
    5(6)-Carboxyrhodamine 110 NHS Ester is the nonsulfonated analog of the BP Fluor 488 dye. The amine-reactive 5(6)-Carboxyrhodamine 110 NHS ester can be used to create bright and photostable green-fluorescent bioconjugates with excitation/emission maxima ~502/527 nm. The conjugates of this dye often used for Fluorescence Correlation Spectroscopy (FCS).
    5(6)-Carboxyrhodamine 110 NHS ester
  • HY-W019997
    PDAM
    PDAM (1-Pyrenyldiazomethane) is a compound 1-Pyrenyldiazomethane with strong biomarker and fluorescence activity. PDAM is used as a stain for cell imaging in histological studies, which can clearly mark specific cell structures. PDAM is also used as a hematological stain to improve the visualization of cellular components and help make more accurate diagnoses.
    PDAM
  • HY-131461
    6-TET Dipivaloate
    6-TET Dipivaloate is a nucleic acid sequencing probe.
    6-TET Dipivaloate
  • HY-N7131R
    Coumarin 6 (Standard)
    Coumarin 6 (Standard) is the analytical standard of Coumarin 6 (HY-N7131). This product is intended for research and analytical applications. Coumarin 6, a fluorescent dye, is used as a fluorescent probe in a microparticle drug delivery system to conduct in vivo tracking, cell uptake, and transport mechanism studies of drug delivery systems (λexc=450 nm, λem=505 nm).
    Coumarin 6 (Standard)
  • HY-D0339
    Disperse Yellow 3
    Disperse Yellow 3 is a yellow dye commonly used for fiber dyeing.
    Disperse Yellow 3
  • HY-W800832
    MB 660R DBCO
    MB 660R DBCO is a bright and photostable far-red dye that emits fluorescence at about 685 nm in the borderline spectral region between far-red and near-IR. Although the absorption maximum is at around 665 nm, this dye can be sufficiently excited by the 633 or 635 nm laser. MB 660R DBCO is water soluble and pH-insensitive from pH 4 to pH 10. MB 660R DBCO is a rhodamine-based dye, and like rhodamine dyes in general, it is very bright and exceptionally photostable.
    MB 660R DBCO
  • HY-D2435
    MTX-PEG-Cy3
    CDDP-PEG-Cy3 is a MTX-PEG conjugate labeled with Cy3 (HY-D0822). The Cy3 fluorophore is commonly used in applications such as immunolabeling, nucleic acid labeling, fluorescence microscopy, and flow cytometry. The maximum emission wavelength of Cy3 is approximately 562-570 nm. Methotrexate (Amethopterin; MTX) (HY-14519), an antimetabolite and antifolate agent, inhibits the enzyme dihydrofolate reductase, thereby preventing the conversion of folic acid into tetrahydrofolate, and inhibiting DNA synthesis. Methotrexate, also an immunosuppressant and antineoplastic agent, is used for the research of rheumatoid arthritis and a number of different cancers (such as acute lymphoblastic leukemia).
    MTX-PEG-Cy3
  • HY-174322
    SHP2-IN-38
    		Chemical
    SHP2-IN-38 is a novel green-fluorescent SHP2 inhibitor with IC50 values of 2.89 μM (SHP2), 8.73 μM (SHP1), 11.08 μM (PTP1B), 33.07 μM (TCPTP). SHP2-IN-38 blocks the SHP2-mediated ERK signaling pathway and inhibits MV4-11 cells proliferation in vitro with IC50 of 7.90 μM. SHP2-IN-38 has an excitation wavelength of 360 nm, with a maximum emission wavelength of 550 nm in DMSO and 540 nm in DMF. SHP2-IN-38 shows green fluorescence imaging in HeLa cells and zebrafish.
    SHP2-IN-38
  • HY-D0514
    Reactive blue 5
    Reactive blue 5 is common textile dyes that can be adsorbed onto single-walled carbon nanotubes (SWCNTs) through electrostatic interactions, allowing the separation of residual dyes.
    Reactive blue 5
  • HY-D2438
    CDDP-PEG-Cy3
    CDDP-PEG-Cy3 is a CDDP-PEG conjugate labeled with Cy3 (HY-D0822). The Cy3 fluorophore is commonly used in applications such as immunolabeling, nucleic acid labeling, fluorescence microscopy, and flow cytometry. The maximum emission wavelength of Cy3 is approximately 562-570 nm. Cisplatin (CDDP) (HY-17394) is an antineoplastic chemotherapy agent by cross-linking with DNA and causing DNA damage in cancer cells. Cisplatin activates ferroptosis and induces autophagy.
    CDDP-PEG-Cy3
  • HY-P3699A
    TNO003 TFA
    TNO003 TFA is a selective fluorogenic substrate for stromelysin-1 (MMP-3). TNO003 TFA has higher selectivity for MMP-3 than MMP-1, MMP-2, MMP-7, MMP-8, MMP-9 and MMP-13. TNO003 TFA can be used for the determination of stromelysin activity (Ex/Em = 360/490 nm).
    TNO003 TFA
  • HY-D0445
    C.I. Pigment orange 16
    C.I. Pigment orange 16 is the most important colorant used to add color or change the color of something and is chemically essentially unaffected by the carrier or medium into which it is incorporated. It can be widely used in textile, medicine, food, cosmetics, plastics, paint, ink, photography and paper industries.
    C.I. Pigment orange 16
Cat. No. Product Name / Synonyms Application Reactivity