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  4. Reference Standards

Reference Standards

Material, sufficiently homogeneous and stable with respect to one or more specified properties, and the uses include the calibration of a measurement system, assessment of a measurement procedure, assigning values to other materials, and quality control and so on.

Reference Standards Related Products (11061):

Cat. No. Product Name Effect Purity Chemical Structure
  • HY-108613R
    JJKK 048 (Standard)
    JJKK 048 (Standard) is the analytical standard of JJKK 048 (HY-108613). This product is intended for research and analytical applications. JJKK 048 is a highly selective and potent monoacylglycerol lipase (MAGL) inhibitor with IC50 values of 214 pM, 275 pM and 363 pM for human, rat, and mouse MAGL. JJKK 048 displays low cross-reactivity with other endocannabinoid targets. JJKK 048 can be used in the research of diseases such as cancer, neurodegenerative diseases, and pain.
    JJKK 048 (Standard)
  • HY-106067AR
    Dazoxiben hydrochloride (Standard)
    Dazoxiben (hydrochloride) (Standard) is the analytical standard of Dazoxiben (hydrochloride). This product is intended for research and analytical applications. Dazoxiben hydrochloride is a potent and orally active thromboxane (TX) synthase inhibitor.
    Dazoxiben hydrochloride (Standard)
  • HY-100811AR
    7-Chlorokynurenic acid sodium salt (Standard)
    7-Chlorokynurenic acid (sodium salt) (Standard) is the analytical standard of 7-Chlorokynurenic acid (sodium salt). This product is intended for research and analytical applications. 7-Chlorokynurenic acid sodium salt (7-CKA sodium salt) is a potent and selective antagonist of the glycine B coagonist site of the N-methyl-D-aspartate (NMDA) receptor (IC50=0.56 μM). 7-Chlorokynurenic acid sodium salt is also a potent inhibitor of the reuptake of glutamate into synaptic vesicles with a Ki of 0.59 μM. 7-Chlorokynurenic acid sodium salt has potent antinociceptive actions after neuraxial delivery.
    7-Chlorokynurenic acid sodium salt (Standard)
  • HY-101840R
    EIPA (Standard)
    EIPA (Standard) is the analytical standard of EIPA. This product is intended for research and analytical applications. EIPA (L593754) is an orally active TRPP3 channel inhibitor with an IC50 of 10.5 μM. EIPA also enhances autophagy by inhibiting Na+/H+-exchanger 3 (NHE3). EIPA inhibits macropinocytosis as well. EIPA can be used in the research of inflammation and cancers, such as gastric cancer, colon carcinoma, pancreatic carcinoma.
    EIPA (Standard)
  • HY-A0106R
    Levamisole (Standard)
    Levamisole (Standard) is the analytical standard of Levamisole. This product is intended for research and analytical applications. Levamisole ((-)-Levamisole), an anthelmintic agent with immunomodulatory properties. Levamisole acts as a positive allosteric modulator (PAM) for the α3β2 (EC50=300 μM) and α3β4 (EC50=100 μM) subtype of nAChRs. Orally active.
    Levamisole (Standard)
  • HY-101943R
    LY 345899 (Standard)
    LY 345899 (Standard) is the analytical standard of LY 345899 (HY-101943). This product is intended for research and analytical applications. LY 345899 is a Folate analog and is a methylene tetrahydrofolate dehydrogenase (MTHFD1; DC301) and MTHFD2 inbhibitor with IC50 values of 96 nM and 663 nM, respectively and a Ki of 18 nM for MTHFD1.
    LY 345899 (Standard)
  • HY-W007324R
    Maleimide (Standard)
    Maleimide (Standard) is the analytical standard of Maleimide (HY-W007324). This product is intended for research and analytical applications. Maleimide can be used for production of antibody-drug conjugate (ADC) which is used in cancer research. Maleimide also be leveraged for the preparation of fluorogenic probe, which is mainly used for the specific detection of thiol analytes.
    Maleimide (Standard)
  • HY-14734R
    Anamorelin (Standard)
    Anamorelin (Standard) (RC-1291 (Standard)) is the analytical standard of Anamorelin (HY-14734). This product is intended for research and analytical applications. Anamorelin (RC-1291) is an orally active Ghrelin receptor agonist with an EC50 of 0.74 nM. Anamorelin can promote appetite, increase body weight, and stimulate the secretion of growth hormone and insulin-like growth factor-1. Anamorelin can be used in the research of anorexia and cancer cachexia.
    Anamorelin (Standard)
  • HY-N7264R
    7α-Hydroxycholesterol (Standard)
    7α-Hydroxycholesterol is a cholesterol oxide and can serve as a biomarker for oxidative stress and lipid peroxidation. 7α-Hydroxycholesterol has cytotoxic and pro-inflammatory activities. 7α-Hydroxycholesterol can also inhibit sterol synthesis and reduce the activity of HMG-CoA reductase. 7α-Hydroxycholesterol can be used in the research of diseases such as diabetes and atherosclerosis.
    7α-Hydroxycholesterol (Standard)
  • HY-77521R
    Dabigatran (ethyl ester hydrochloride) (Standard)
    Dabigatran ethyl ester hydrochloride (Standard) is the analytical standard of Dabigatran ethyl ester hydrochloride (HY-77521). This product is intended for research and analytical applications. Dabigatran ethyl ester hydrochloride is a potent inhibitor of ribosyldihydronicotinamide dehydrogenase (NQO2) with an IC50 value of 0.8 μM and a thrombin inhibitor.
    Dabigatran (ethyl ester hydrochloride) (Standard)
  • HY-W007557R
    4-Bromo-2-fluoroaniline (Standard)
    4-Bromo-2-fluoroaniline (Standard)
  • HY-106929R
    Moxilubant (Standard)
    Moxilubant (CGS 25019C free base) Standard is the analytical standard of Moxilubant (HY-106929). This product is intended for research and analytical applications. Moxilubant (CGS 25019C free base) is an orally active BLT1 antagonist. Moxilubant inhibits LTB4 signaling with a potency of 2-4 nM. Moxilubant blocks LTB4-induced neutrophil functions. Moxilubant inhibits ear edema and neutrophil infiltration in mice. Moxilubant can be used in research related to chronic obstructive pulmonary disease.
    Moxilubant (Standard)
  • HY-17627R
    Avacopan (Standard)
    Avacopan (Standard) is the analytical standard of Avacopan. This product is intended for research and analytical applications. Avacopan (CCX168) is a potent, selective and orally available complement 5a receptor (C5aR) inhibitor with an IC50 of 0.1 nM.
    Avacopan (Standard)
  • HY-107986R
    GNE-6776 (Standard)
    GNE-6776 (Standard) is the analytical standard of GNE-6776 (HY-107986). This product is intended for research and analytical applications. GNE-6776 is a selective and orally bioavailable USP7 inhibitor.
    GNE-6776 (Standard)
  • HY-78086R
    m-Tolualdehyde (Standard)
    m-Tolualdehyde (Standard) is the analytical standard of m-Tolualdehyde (HY-78086). This product is intended for research and analytical applications. m-Tolualdehyde (3-Methylbenzaldehyde) is an aldehyde metabolite produced by m-xylene metabolism, and it bidirectionally regulates the CYP 2B1, CYP 2E1, and CYP 4B1 isoenzymes in the respiratory tract of rats. m-Tolualdehyde serves as an oxidation substrate and carbon source for Pseudomonas Pxy, and it can be oxidized to m-toluic acid in an NAD+ -dependent manner. m-Tolualdehyde exerts a dose-dependent inhibitory effect on CYP 2B1 and CYP 2E1 in the nasal mucosa and lungs of rats, and a dose-dependent activating effect on pulmonary CYP 4B1. m-Tolualdehyde can form aldehyde-heme adducts with the heme group of cytochrome P450. m-Tolualdehyde can be used in studies related to metabolic enzymes in the respiratory tract of rats.
    m-Tolualdehyde (Standard)
  • HY-B2029R
    Phosalone (Standard)
    Phosalone (Standard) is the analytical standard of Phosalone. This product is intended for research and analytical applications.
    Phosalone (Standard)
  • HY-N2370R
    24-Hydroxycholesterol (Standard)
    24-Hydroxycholesterol is a natural sterol, which serves as a positive allosteric modulator of N-Methyl-d-Aspartate (NMDA) receptorsR, and a potent activator of the transcription factors LXR.
    24-Hydroxycholesterol (Standard)
  • HY-103712AR
    Samuraciclib hydrochloride (Standard)
    Samuraciclib hydrochloride (Standard) is the analytical standard of Samuraciclib hydrochloride (HY-103712A). This product is intended for research and analytical applications. Samuraciclib hydrochloride (CT7001 hydrochloride) is a potent, selective, ATP-competitive and orally active CDK7 inhibitor, with an IC50 of 41 nM. Samuraciclib hydrochloride displays 45-, 15-, 230- and 30-fold selectivity over CDK1, CDK2 (IC50 of 578 nM), CDK5 and CDK9, respectively. Samuraciclib hydrochloride inhibits the growth of breast cancer cell lines with GI50 values between 0.2-0.3 µM. Samuraciclib hydrochloride has anti-tumor effects.
    Samuraciclib hydrochloride (Standard)
  • HY-I0432R
    Cinnarizine impurity 7 (Standard)
    Methanesulfonic acid 3-(3-trifluoromethylphenyl)propyl ester (Standard) is the analytical standard of Methanesulfonic acid 3-(3-trifluoromethylphenyl)propyl ester. This product is intended for research and analytical applications.
    Cinnarizine impurity 7 (Standard)
  • HY-107128R
    Ampreloxetine hydrochloride (Standard)
    Ampreloxetine hydrochloride (Standard) (TD-9855 hydrochloride (Standard)) is the analytical standard of Ampreloxetine (hydrochloride) (HY-107128). This product is intended for research and analytical applications. Ampreloxetine (TD-9855) hydrochloride is an orally active and CNS-penetrant inhibitor of Norepinephrine transporter (NET) and Serotonin 5-HT uptake transporter (SERT), but not Dopamine transporter (DAT). Ampreloxetine hydrochloride binds norepinephrine transporters (NET) and serotonin transporters (SERT) with EC50 values of 11.7 ng/mL and 50.8 ng/mL, respectively, in plasma.
    Ampreloxetine hydrochloride (Standard)