2. Others Neuronal Signaling
  3. Reference Standards Serotonin Transporter
  4. Ampreloxetine hydrochloride (Standard)

Ampreloxetine hydrochloride (Standard)  (Synonyms: TD-9855 hydrochloride (Standard))

Cat. No.: HY-107128R
Handling Instructions Technical Support

Ampreloxetine hydrochloride (Standard) (TD-9855 hydrochloride (Standard)) is the analytical standard of Ampreloxetine (hydrochloride) (HY-107128). This product is intended for research and analytical applications. Ampreloxetine (TD-9855) hydrochloride is an orally active and CNS-penetrant inhibitor of Norepinephrine transporter (NET) and Serotonin 5-HT uptake transporter (SERT), but not Dopamine transporter (DAT). Ampreloxetine hydrochloride binds norepinephrine transporters (NET) and serotonin transporters (SERT) with EC50 values of 11.7 ng/mL and 50.8 ng/mL, respectively, in plasma.

For research use only. We do not sell to patients.

Ampreloxetine hydrochloride (Standard)

Ampreloxetine hydrochloride (Standard) Chemical Structure

CAS No. : 1227056-87-2

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Ampreloxetine hydrochloride (Standard) Related Antibodies

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Description

Ampreloxetine hydrochloride (Standard) (TD-9855 hydrochloride (Standard)) is the analytical standard of Ampreloxetine (hydrochloride) (HY-107128). This product is intended for research and analytical applications. Ampreloxetine (TD-9855) hydrochloride is an orally active and CNS-penetrant inhibitor of Norepinephrine transporter (NET) and Serotonin 5-HT uptake transporter (SERT), but not Dopamine transporter (DAT). Ampreloxetine hydrochloride binds norepinephrine transporters (NET) and serotonin transporters (SERT) with EC50 values of 11.7 ng/mL and 50.8 ng/mL, respectively, in plasma[1].

Molecular Weight

357.80

Formula

C18H19ClF3NO
CAS No.
SMILES

FC1=C(C(F)=CC(F)=C1)OCC2=C(C3CCNCC3)C=CC=C2.Cl
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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Ampreloxetine hydrochloride (Standard) Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Ampreloxetine hydrochloride (Standard)1227056-87-2TD-9855 hydrochloride (Standard)Reference StandardsSerotonin Transporter5-HTTSERTSLC6A4orally activeCNS-penetrantNorepinephrine transporterSerotonin 5-HT uptake transporterDopamine transporterInhibitorinhibitorinhibit

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