2. Signaling Pathways
  3. Others
  4. Reference Standards

Reference Standards

Material, sufficiently homogeneous and stable with respect to one or more specified properties, and the uses include the calibration of a measurement system, assessment of a measurement procedure, assigning values to other materials, and quality control and so on.

Reference Standards Related Products (10971):

Cat. No. Product Name Effect Purity Chemical Structure
  • HY-I0534R
    Canagliflozin impurity 5 (Standard)
    2-(5-Bromo-2-methylbenzyl)thiophene (Standard) is the analytical standard of 2-(5-Bromo-2-methylbenzyl)thiophene. This product is intended for research and analytical applications.
    Canagliflozin impurity 5 (Standard)
  • HY-W010526R
    Cyclohexanemethanol (Standard)
    Cyclohexanemethanol (Standard) is the analytical standard of Cyclohexanemethanol. This product is intended for research and analytical applications.
    Cyclohexanemethanol (Standard)
  • HY-W003969R
    Aminopicoline (Standard)
    Aminopicoline (Standard) is the analytical standard of Aminopicoline. Aminopicoline (Ascensil) is a potent and non-selective inhibitor of nitric oxide synthase (NOS) isoenzymes (iNOS, nNOS, eNOS). Aminopicoline competes with arginine at the substrate-binding site of nitric oxide synthase, reduces cellular nitric oxide production, inhibits the elevation of plasma nitrate, increases mean arterial pressure at high doses, and also serves as a basis for radiolabeled ligands to localize nitric oxide synthase binding sites. Aminopicoline can be used in the research of diseases associated with septic shock, joint inflammation, intestinal inflammation, and CNS inflammation。
    Aminopicoline (Standard)
  • HY-108933R
    JK-P3 (Standard)
    JK-P3 (Standard) is the analytical standard of JK-P3 (HY-108933). This product is intended for research and analytical applications. JK-P3 is a potent and pan VEGFR2 inhibitor, with IC50s of 7.83 μM, 27 μM and 5.18 μM for VEGFR2, FGFR1 and FGFR3, respectively. JK-P3 can inhibit VEGF-A-stimulated VEGFR2 activation and intracellular signalling, also inhibits endothelial monolayer wound closure and angiogenesis, as well as fibroblast growth factor receptor Kinase activity in vitro. JK-P3 has anti-angiogenic activity.
    JK-P3 (Standard)
  • HY-B1738AR
    Pralidoxime iodide (Standard)
    Pralidoxime (iodide) (Standard) is the analytical standard of Pralidoxime (iodide). This product is intended for research and analytical applications. Pralidoxime iodide is a potent reactivator of acetylcholinesterase (AChE). Pralidoxime iodide reactivates nerve agent-inhibited AChE via direct nucleophilic attack by the oxime moiety on the phosphorus center of the bound nerve agent. Pralidoxime iodide is an antidote for organophosphate poisoning.
    Pralidoxime iodide (Standard)
  • HY-103597R
    Thalidomide-O-COOH (Standard)
    Thalidomide-O-COOH (Standard) is the analytical standard of Thalidomide-O-COOH (HY-103597). This product is intended for research and analytical applications. Thalidomide-O-COOH (Cereblon ligand 3) is the Thalidomide-based Cereblon ligand used in the recruitment of CRBN protein. Thalidomide-O-COOH (Cereblon ligand 3) can be connected to the ligand for protein by a linker to form PROTACs.
    Thalidomide-O-COOH (Standard)
  • HY-108504R
    Co 102862 (Standard)
    Co 102862 (Standard) is the analytical standard of Co 102862 (HY-108504). This product is intended for research and analytical applications. Co 102862 (V 102862) is a potent, broad-spectrum, state-dependent Na+ channel blocker. Co 102862 is also an orally active anticonvulsant.
    Co 102862 (Standard)
  • HY-100754CR
    Ritlecitinib tosylate (Standard)
    Ritlecitinib (tosylate) (Standard) is the analytical standard of Ritlecitinib (tosylate) (HY-100754C). This product is intended for research and analytical applications. Ritlecitinib (PF-06651600) tosylate is a highly selective, orally active, irreversible covalent JAK3 inhibitor (IC50=33 nM) without inhibitory activity towards JAK1, JAK2, and TYK2 (IC50 >10 μ M). Ritlecitinib tosylate rapidly inactivates the JAK3 kinase, and blocks signaling and downstream STAT phosphorylation mediated by common gamma chain cytokines such as IL-2 and IL-15. Ritlecitinib tosylate can inhibit Th1/Th17 cell differentiation and function, and effectively suppress preclinical animal models such as alopecia areata, adjuvant-induced arthritis (AIA), and experimental autoimmune encephalomyelitis (EAE).
    Ritlecitinib tosylate (Standard)
  • HY-14261R
    Vilazodone Hydrochloride (Standard)
    Vilazodone (Hydrochloride) (Standard) is the analytical standard of Vilazodone (Hydrochloride). This product is intended for research and analytical applications. Vilazodone Hydrochloride (EMD 68843 Hydrochloride) is a serotonin transporter (SER) inhibitor and 5-HT1A receptor partial agonist.
    Vilazodone Hydrochloride (Standard)
  • HY-176114
    2-Methyl-α-pyrrolidinoisohexanophenone hydrochloride
    2-Methyl-α-pyrrolidinoisohexanophenone (hydrochloride) (2-Methyl-α-PiHP (hydrochloride)) is a drug derivative.
    2-Methyl-α-pyrrolidinoisohexanophenone hydrochloride
  • HY-W020043R
    Pyribencarb (Standard)
    Pyribencarb (Standard) is the analytical standard of Pyribencarb. This product is intended for research and analytical applications. Pyribencarb is a benzylcarbamate-type fungicide, which is active against a wide range of plant pathogenic fungi. Pyribencarb is a potent Qo inhibitor of cytochrome b. Pyribencarb is especially active against Botrytis cinerea and Sclerotinia sclerotirum.
    Pyribencarb (Standard)
  • HY-N2156R
    Paeonolide (Standard)
    Paeonolide (Standard) is the analytical standard of Paeonolide (HY-N2156). This product is intended for research and analytical applications. Paeonolide, found in Paeonia suffruticosa, is an ERK1/2 activator. Paeonolide promotes early and late osteoblast differentiation, stimulates pre-osteoblast transmigration, and activates the BMP-Smad1/5/8, Wnt-β-catenin, JNK and p38 pathways. Paeonolide can be used for the research of osteoporosis, periodontitis.
    Paeonolide (Standard)
  • HY-Y0145R
    Methyl 4-methylbenzoate (Standard)
    Methyl 4-methylbenzoate (Standard) is the analytical standard of Methyl 4-methylbenzoate. This product is intended for research and analytical applications.
    Methyl 4-methylbenzoate (Standard)
  • HY-N0481R
    Roburic acid (Standard)
    Roburic acid (Standard) is the analytical standard of Roburic acid. This product is intended for research and analytical applications. Roburic acid acts as an anti-inflammatory, anti-tumor and osteoclastogenesis inhibitor, with a Ki of 7.066 μM against human TNF, an IC50 of 9 μM against human COX-2, and an IC50 of 5 μM against ovine COX-1. Roburic acid reduces the production of inflammatory mediators such as NO and IL-6 in macrophages by inhibiting the NF-κB and MAPK (p38/JNK) pathways. By competitively inhibiting the TNF-TNF-R1 interaction, Roburic acid blocks the downstream NF-κB signaling pathway, thereby inducing cell cycle arrest and apoptosis in cancer cells. Roburic acid specifically inhibits osteoclastogenesis and bone resorption by suppressing the RANKL/TRAF6/NF-κB/NFATc1 axis. Roburic acid can be used in research related to osteolytic diseases such as osteoporosis, colorectal cancer and inflammatory diseases.
    Roburic acid (Standard)
  • HY-W010669R
    L-Thyroxine sodium xhydrate (Standard)
    L-Thyroxine sodium xhydrate (Standard) is the analytical standard of L-Thyroxine sodium xhydrate. This product is intended for research and analytical applications. L-Thyroxine sodium xhydrate (Levothyroxine; T4) is a synthetic hormone in the treatment of hypothyroidism. DIO enzymes convert biologically active hormone (Triiodothyronine,T3) from L-Thyroxine (T4).
    L-Thyroxine sodium xhydrate (Standard)
  • HY-W014590R
    (S)-Thioctic acid (Standard)
    (S)-Thioctic acid ((S)-lipoic acid; (S)-5-(1,2-Dithiolan-3-yl)pentanoic acid) is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
    (S)-Thioctic acid (Standard)
  • HY-W010249R
    H-D-Phg-OH (Standard)
    H-D-Phg-OH (Standard) is the analytical standard of H-D-Phg-OH. This product is intended for research and analytical applications. H-D-Phg-OH is a Glycine (HY-Y0966) derivative.
    H-D-Phg-OH (Standard)
  • HY-W016286R
    2,6-Dithiopurine (Standard)
    2,6-Dithiopurine (2,6-Dimercaptopurine) is a nucleophilic scavenger for electrophilic carcinogens. 2,6-Dithiopurine abolishes both DNA adduct formation and the initiation of carcinogenesis.
    2,6-Dithiopurine (Standard)
  • HY-B0135AR
    Furosemide sodium (Standard)
    Furosemide (sodium) (Standard) is the analytical standard of Furosemide (sodium). This product is intended for research and analytical applications. Furosemide sodium is a potent and orally active inhibitor of Na+/K+/2Cl- (NKCC) cotransporter, NKCC1 and NKCC2. Furosemide sodium is also a GABAA receptors antagonist and displays 100-fold selectivity for α6-containing receptors than α1-containing receptors. Furosemide sodium acts as a loop diuretic and used for the study of congestive heart failure, hypertension and edema.
    Furosemide sodium (Standard)
  • HY-10499R
    PH-064 (Standard)
    PH-064 (Standard) is the analytical standard of PH-064 (HY-10499). This product is intended for research and analytical applications. PH-064 (BIM-46187) is an orally active inhibitor of the heterotrimeric G-protein complex. PH-064 inhibits SERT activity and attenuates shear stress-induced Akt phosphorylation. PH-064 has potent anti-hyperalgesia activity. PH-064 inhibits G protein-coupled receptor-dependent tumorigenesis. PH-064 can be used in the study of pain (e.g., inflammatory pain, neuropathic pain), GPCR-dependent tumors, and inflammatory lung injury.
    PH-064 (Standard)