2. Immunology/Inflammation
  3. Toll-like Receptor (TLR)
  4. Agatolimod sodium

Agatolimod sodium  (Synonyms: ODN 2006 sodium; ODN 7909 sodium; PF-3512676 sodium; CpG 7909 sodium)

Cat. No.: HY-150218 Pureza: 99.13%
COA
SDS
Instrucciones de manejo Technical Support

Agatolimod sodium (ODN 2006) is a class B CpG ODN and is a TLR9 agonist. Agatolimod sodium can be used as vaccine adjuvant. Agatolimod sodium can be used for the research of cancer. Sequence: 5’-TCGTCGTTTTGTCGTTTTGTCGTT-3’.

Para uso exclusivo en investigación. No vendemos a pacientes.

DNA, d(P-thio)(T-C-G-T-C-G-T-T-T-T-G-T-C-G-T-T-T-T-G-T-C-G-T-T), tricosasodium salt

Agatolimod sodium Estructura química

No. CAS : 541547-35-7

Tamaño Precio Stock Cantidad
1 mg En stock
5 mg En stock
10 mg En stock
25 mg En stock
50 mg En stock
100 mg En stock
200 mg   Obtener un presupuesto  
500 mg   Obtener un presupuesto  

* Seleccione Cantidad antes de agregar artículos.

This product is a controlled substance and not for sale in your territory.

Revisión del cliente

Based on 1 publication(s) in Google Scholar

Other Forms of Agatolimod sodium:

Agatolimod sodium Related Antibodies

Top Publications Citing Use of Products

1 Publications Citing Use of MCE Agatolimod sodium

Ver todos los productos específicos de isoformas Toll-like Receptor (TLR):

Ver todas las isoformas
TLR3 TLR8 TLR9 TLR2 TLR4 TLR7 TLR1 TLR6

  • Actividad biológica

  • Pureza y Documentación

  • Referencias

  • Revisión del cliente

Descripciòn

Agatolimod sodium (ODN 2006) is a class B CpG ODN and is a TLR9 agonist. Agatolimod sodium can be used as vaccine adjuvant. Agatolimod sodium can be used for the research of cancer. Sequence: 5’-TCGTCGTTTTGTCGTTTTGTCGTT-3’[1][2].

IC50 & Target[1]

TLR9

 

In Vitro

Agatolimod sodium (ODN 2006) (10 μg/mL; 24 and 48 h) increases radiation sensitivity of radiation-resistant human lung adenocarcinoma cell line by overexpression of TLR9[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Agatolimod sodium Related Antibodies
Ensayo clínico
Peso molecular

7699 (free acid)

No. CAS
Appearance

Solid

Color

White to off-white

Sequence

DNA, d(P-thio)(T-C-G-T-C-G-T-T-T-T-G-T-C-G-T-T-T-T-G-T-C-G-T-T)
SMILES

[Agatolimod (sodium)]
Envío

Room temperature in continental US; may vary elsewhere.
Almacenamiento

-20°C, sealed storage, away from moisture

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

Solvente y solubilidad
In Vitro: 

H2O : 100 mg/mL (Need ultrasonic)

  • Calculadora de molaridad

  • Calculadora de dilución

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
This product has good water solubility, please refer to the measured solubility data in water/PBS/Saline for details.
The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only.If necessary, please contact MedChemExpress (MCE).
Pureza y Documentación

Purity: 99.13%

SDS (252 KB)

COA (244 KB) LCMS (321 KB)

Instrucciones de manejo (2242 KB)
Referencias
  • No file chosen (Maximum size is: 1024 Kb)
  • If you have published this work, please enter the PubMed ID.
  • Your name will appear on the site.

Agatolimod sodium Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Agatolimod541547-35-7ODN 2006ODN 7909PF-3512676CpG 7909ODN2006ODN-2006ODN7909ODN-7909PF3512676PF 3512676CpG7909CpG-7909Toll-like Receptor (TLR)vaccine adjuvantA549radiation sensitivitycancerInhibitorinhibitorinhibit

Productos vistos recientemente:

Consulta en línea

Your information is safe with us. * Required Fields.

Nombre del producto

  

Requested Quantity *

Nombre del solicitante *

 

Saludo

Direcciòn del E-mail *

 

Número de teléfono *

Department

 

Nombre de la Organizaciòn *

City

Provincia

Country or Region *

      

Observaciones

Consulta para venta a granel

Inquiry Information

Nombre del producto:
Agatolimod sodium
Cat. No.:
HY-150218
Cantidad:
MCE Japan Authorized Agent:

Revisión del cliente

Thank You for Your Feedback!

Request for HNMR Report

Please fill out this form to request the QC report. We will send it to your Email address shortly.

Your information is safe with us. * Required Fields.

Nombre del producto

  

Lot #

Nombre del solicitante *

 

Direcciòn del E-mail *

Número de teléfono

 

Department *

Nombre de la Organizaciòn *

 

Country or Region *

Observaciones

SAFETY DATA SHEET (SDS)

English - EN (252 KB) Français - FR (252 KB) Deutsch - DE (252 KB) Norwegian - NO (252 KB) Español - ES (252 KB) Swedish - SV (252 KB) Italian - IT (252 KB) Korean - KR (252 KB) Portuguese - PT (252 KB)

Request for HNMR Report

We have received your request and will respond to you as soon as possible.