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Ammonium iron(III) citrate

(Synonyms: Ammonium ferric citrate; FAC)
36 Cited Publications
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Based on 36 publication(s) in Google Scholar

Ammonium iron(III) citrate (Ammonium ferric citrate), a physiological form of nonetransferrin-bound iron, induces intracellular iron overload to cause ferroptosis. Ammonium iron(III) citrate can enhance protein production.

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  • Purity: 98.0%
  • CAS No.: 1185-57-5
  • Formula: C6H8O7.xFe.xH3N
  • Storage:

    Store at room temperature, keep dry and cool.

    In solvent   -80°C, 1 year , -20°C, 6 months
  • Ammonium iron(III) citrate Chemical Structure
    Ammonium iron(III) citrate Chemical Structure
  • Experimental Validation Results for Ammonium iron(III) citrate
  • Experimental Validation Results for Ammonium iron(III) citrate
  • Experimental Validation Results for Ammonium iron(III) citrate
  • Experimental Validation Results for Ammonium iron(III) citrate
  • Experimental Validation Results for Ammonium iron(III) citrate
CAS No.: 1185-57-5
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  • Ammonium iron(III) citrate Chemical Structure
    Ammonium iron(III) citrate Chemical Structure
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    Ammonium iron(III) citrate purchased from MedChemExpress. Usage Cited in: Adv Sci (Weinh). 2025 Nov 7:e18323. [Abstract]

    Customer Validation
     Immunoblot analysis of FDX1 and mitochondrial marker TOMM20 in OSRC2 cells treated for 24 h with either FAC (Ammonium iron(III) citrate) 0–4 μM.

  • 1/16

    Ammonium iron(III) citrate purchased from MedChemExpress. Usage Cited in: Adv Sci (Weinh). 2025 Jul;12(28):e2505359. [Abstract]

    Customer Validation
     Ferroptosis was induced by erastin or FAC (Ammonium iron(III) citrate; 0-1600 μM) with different doses, and cell viability was analyzed by the CCK-8 after cells were treated for 2 days.

  • 1/16

    Ammonium iron(III) citrate purchased from MedChemExpress. Usage Cited in: Adv Sci (Weinh). 2025 Jul;12(28):e2505359. [Abstract]

    Customer Validation
     Intracellular ROS was assessed using the DCFH-DA probe after being treated with 30 µM erastin or 500 µM FAC (Ammonium iron(III) citrate) for 4 h.

  • 1/16

    Ammonium iron(III) citrate purchased from MedChemExpress. Usage Cited in: Adv Sci (Weinh). 2025 Jul;12(28):e2505359. [Abstract]

    Customer Validation
     Intracellular Fe2+ levels under 30 µM erastin or 500 µM FAC (Ammonium iron(III) citrate) treatment for 4 h were detected with the RhoNox-1(1μM; 1 h) fluorescent probe.

  • 1/16

    Ammonium iron(III) citrate purchased from MedChemExpress. Usage Cited in: Adv Sci (Weinh). 2025 Jul;12(28):e2505359. [Abstract]

    Customer Validation
     Representative images of ferroptotic cells among iPSC-RPE cells, De-iPSC-RPE cells, and iRPE cells treated with 30 µM erastin or 500 µM FAC (Ammonium iron(III) citrate) for 2 days.

  • Ammonium iron(III) citrate