1. Apoptosis
  2. Ferroptosis
  3. Ammonium iron(III) citrate

Ammonium iron(III) citrate (Synonyms: Ammonium ferric citrate; FAC)

Cat. No.: HY-B1645
Handling Instructions

Ammonium iron(III) citrate (Ammonium ferric citrate), a physiological form of nonetransferrin-bound iron, induces intracellular iron overload to cause ferroptosis. Ammonium iron(III) citrate can enhance protein production.

For research use only. We do not sell to patients.

Ammonium iron(III) citrate Chemical Structure

Ammonium iron(III) citrate Chemical Structure

CAS No. : 1185-57-5

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5 mg USD 50 In-stock
Estimated Time of Arrival: December 31
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Description

Ammonium iron(III) citrate (Ammonium ferric citrate), a physiological form of nonetransferrin-bound iron, induces intracellular iron overload to cause ferroptosis[1]. Ammonium iron(III) citrate can enhance protein production[2].

In Vitro

Ammonium iron(III) citrate (Ammonium ferric citrate; 1, 5, 10, 15 mM; 24 hours) with 5 mM induces cell death in HT1080 cells. AML12 cells were highly resistant to Ammonium iron(III) citrate, as they maintained cell viability about 80%. Ammonium iron(III) citrate can be actively transported into cells by specific transporter[1].
Ammonium iron(III) citrate (6, 12, 18 mg/L) has a higher biomas for Chlorella vulgaris FSP-E (CV) in BG-11 medium with 12 mg/L and 18 mg/L[2].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Formula

C₆H₈O₇.xFe.xH₃N

CAS No.
SMILES

OC(CC(C(O)=O)(O)CC(O)=O)=O.[x Fe(III)].[x NH3]

Shipping

Room temperature in continental US; may vary elsewhere.

Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

H2O : 33.33 mg/mL (Need ultrasonic)

DMSO : < 1 mg/mL (ultrasonic) (insoluble or slightly soluble)

References
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Keywords:

Ammonium iron(III)Ammonium ferric FACFerroptosisHT1080AML12ironInhibitorinhibitorinhibit

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Ammonium iron(III) citrate
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