Anti-Glycophorin A (type M) Antibody (6A7M) 

Anti-Glycophorin A (type M) Antibody (6A7M) is a kind of mouse IgG1 κ chimeric antibody inhibitor, targeting to human Glycophorin A (type M). Anti-Glycophorin A (type M) reacts with the human glycophorin A (GPA) M allele also known as CD235a. Anti-Glycophorin A (type M) can be used for the research of infection, such as human immunodeficiency virus (HIV)^[1].

Mouse IgG1 kappa

Mouse IgG1 kappa, Isotype Control

Mouse

Glycophorin A (type M)

Anti-Glycophorin A (type M) Antibody (6A7M) (2.5-10 μg/mL) reduces the binding of human immunodeficiency virus (HIV)-1 to both CD71⁺ erythroid cells (CECs) and red blood cells (RBCs)^[1].
Anti-Glycophorin A (type M) Antibody (6A7M) (5-10 μg/mL) abrogates the trans-infection of HIV-1 by CECs to already activated autologous CD4⁺ T cells^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

14934  [NCBI]

P14220

in vitro GPA blockade

Unconjugated

The product can be reconstituted/diluted with sterile PBS or saline.

150 kDa

[Anti-Glycophorin A (type M) Antibody (6A7M)]

Please refer to the lot-specific COA for specific buffer information.

Please store the product under the recommended conditions in the Certificate of Analysis.

• [1]. Namdar A, et al. CD71+ Erythroid Cells Exacerbate HIV-1 Susceptibility, Mediate trans-Infection, and Harbor Infective Viral Particles. mBio. 2019 Nov 26;10(6):e02767-19.