1. Apoptosis
  2. Bcl-2 Family Apoptosis
  3. anti-TNBC agent-3

anti-TNBC agent-3 (compound 3g) is an apoptosis inducer with anti-cancer cell proliferation activity. anti-TNBC agent-3 inhibits tumor growth and metastasis in triple-negative breast cancer (TNBC) xenograft models.

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anti-TNBC agent-3

anti-TNBC agent-3 화학구조

CAS No. : 2422001-25-8

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제품 설명

anti-TNBC agent-3 (compound 3g) is an apoptosis inducer with anti-cancer cell proliferation activity. anti-TNBC agent-3 inhibits tumor growth and metastasis in triple-negative breast cancer (TNBC) xenograft models[1].

IC50 & Target

Bcl-2

 

In Vitro

anti-TNBC agent-3 (compound 3g) inhibits K562 and HepG2 proliferation with IC50s of 0.24 μM and 0.25 μM, respectively[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

In Vivo

anti-TNBC agent-3 (compound 3g) (10 mg/kg, 20 mg/kg; ip) inhibits tumor growth and metastasis in a mouse triple-negative breast cancer (TNBC) xenograft model[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

분자량

539.66

화학식

C29H39F2N7O

CAS No.
SMILES

OCCN1CCC(C2CCN(C3=NC(N(C4CCCC4)C=N5)=C5C(NCC6=CC(F)=C(F)C=C6)=N3)CC2)CC1

선적

Room temperature in continental US; may vary elsewhere.

보관

Please store the product under the recommended conditions in the Certificate of Analysis.

순도&문서
References
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anti-TNBC agent-3 Related Classifications

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The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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The dilution calculator equation

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This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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상품명:
anti-TNBC agent-3
Cat. No.:
HY-155251
수량:
MCE Japan Authorized Agent: