2. TGF-beta/Smad
  3. TGF-β Receptor
  4. Bintrafusp alfa

Bintrafusp alfa  (Synonyms: M7824; MSB0011359C)

Art. -Nr.: HY-P99480 Reinheit: 97.96%
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Bintrafusp alfa (M 7824) is a first-in-class bifunctional fusion protein composed of the extracellular domain of TGF-βRII fused to a human IgG1 mAb blocking programmed cell death ligand. Bintrafusp alfa can be used for the research of cancer.

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CAS. Nr. : 1918149-01-5

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Bintrafusp alfa Related Antibodies

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Beschreibung

Bintrafusp alfa (M 7824) is a first-in-class bifunctional fusion protein composed of the extracellular domain of TGF-βRII fused to a human IgG1 mAb blocking programmed cell death ligand. Bintrafusp alfa can be used for the research of cancer[1].

Isotype

Human IgG1 lambda
Recommend Isotype Controls
In Vitro

Bintrafusp alfa can confer long-term protective immunity, decrease regulatory T-cell function, substantially increase CD8+ T cell and natural killer cell infiltration, and decrease myeloid-derived suppressor cell infiltration within tumors[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Bintrafusp alfa Related Antibodies
Klinische Studie
Application

ELISA, FACS, Functional assay
Conjugated

Unconjugated
Reconsititution

The product can be reconstituted/diluted with sterile PBS or saline.
Molekulargewicht

177.21 kDa

CAS. Nr.
Appearance

Liquid

Color

Colorless to light yellow

SMILES

[Bintrafusp alfa]
Versand

Shipping with dry ice.
Formulation

Please refer to the lot-specific COA for specific buffer information.
Speicherung

Please store the product under the recommended conditions in the Certificate of Analysis.
Format
  • Human IgG1 lambda
Reinheit & Dokumentation
Verweise
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Bintrafusp alfa Related Classifications

  • Molaritätsrechner

  • Verdünnungsrechner

Die Formel zur Berechnung von Molaritäten

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass   Concentration   Volume   Molecular Weight *
= × ×

The dilution calculator equation

Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)

Diese Gleichung wird häufig abgekürzt als: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Bintrafusp alfa1918149-01-5M7824 MSB0011359CM 7824M-7824TGF-β ReceptorTransforming growth factor beta receptorsbifunctional fusion proteinTGF-βRIIIgG1mAbInhibitorinhibitorinhibit

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