2. PROTAC
  3. Ligands for E3 Ligase
  4. CCW16

CCW16 is a cofactor for the synthesis of protein degraders, such as PROTACs CCW 28-3 (HY-156774).

연구목적의 판매만을 진행합니다. 환자를 대상으로 한 판매는 하지 않습니다.

CCW16

CCW16 화학구조

CAS No. : 2361138-33-0

사이즈 가격 재고 수량
무료 샘플 (0.1 - 0.2 mg)   지금 신청하기  
Solid + Solvent (Highly Recommended)
10 mM * 1 mL in DMSO
ready for reconstitution
 해외재고보유
Solution
10 mM * 1 mL in DMSO 해외재고보유
Solid
5 mg 해외재고보유
10 mg 해외재고보유
25 mg 해외재고보유
50 mg 해외재고보유
100 mg 해외재고보유
200 mg   견적 받기  
500 mg   견적 받기  

* 장바구니에 담기 전 물품의 수량을 선택해 주십시오.

This product is a controlled substance and not for sale in your territory.

고객리뷰

Based on 1 Customer Validation

CCW16 Related Antibodies

Top Publications Citing Use of Products

View All Ligands for E3 Ligase Isoform Specific Products:

View All Isoforms
von Hippel-Lindau (VHL) MDM2 Cereblon IAP KLHDC2 Fbxo3 RNF4 DCAF11 DCAF1 UHRF1 TRIM21 NEURL1B KLHL41

  • Biological Activity

  • 순도&문서

  • References

  • 고객리뷰

제품 설명

CCW16 is a cofactor for the synthesis of protein degraders, such as PROTACs CCW 28-3 (HY-156774).

IC50 & Target

RNF4

 

분자량

381.85

화학식

C22H20ClNO3
CAS No.
Appearance

Solid

Color

Light yellow to yellow

SMILES

O=C(N(CC1=CC=CC=C1)C2=CC=C(OC3=CC=C(OC)C=C3)C=C2)CCl
선적

Room temperature in continental US; may vary elsewhere.
보관
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
용액&용해도
In Vitro: 

DMSO : 25 mg/mL (65.47 mM; ultrasonic and warming and heat to 60°C; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.6188 mL 13.0941 mL 26.1883 mL
5 mM 0.5238 mL 2.6188 mL 5.2377 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

  • 몰농도 계산기

  • 농도 희석 계산기

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
순도&문서
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 2.6188 mL 13.0941 mL 26.1883 mL 65.4707 mL
5 mM 0.5238 mL 2.6188 mL 5.2377 mL 13.0941 mL
10 mM 0.2619 mL 1.3094 mL 2.6188 mL 6.5471 mL
15 mM 0.1746 mL 0.8729 mL 1.7459 mL 4.3647 mL
20 mM 0.1309 mL 0.6547 mL 1.3094 mL 3.2735 mL
25 mM 0.1048 mL 0.5238 mL 1.0475 mL 2.6188 mL
30 mM 0.0873 mL 0.4365 mL 0.8729 mL 2.1824 mL
40 mM 0.0655 mL 0.3274 mL 0.6547 mL 1.6368 mL
50 mM 0.0524 mL 0.2619 mL 0.5238 mL 1.3094 mL
60 mM 0.0436 mL 0.2182 mL 0.4365 mL 1.0912 mL
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CCW16 Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

CCW162361138-33-0CCW 16CCW-16Ligands for E3 LigaseE3 ligase-recruiting MoietyE3 ubiquitin ligaseRNF4Inhibitorinhibitorinhibit

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대량구매 문의

Inquiry Information

상품명:
CCW16
Cat. No.:
HY-143346
수량:
MCE Japan Authorized Agent:

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