CCW 28-3
Based on 1 Customer Validation
CCW 28-3 is a PROTAC-based BRD4 degrader in a proteasome- and RNF4-dependent manner.
(Pink: BRD4 ligand (HY-78695); Blue: RNF4 ligand (HY-143346); Black: linker (HY-170384)).
For research use only. We do not sell to patients.
- Purity: 99.38%
- CAS No.: 2361142-23-4
- Formula: C44H42Cl2N6O4S
- Molecular Weight:821.81
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Storage:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
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Biological Activity
Chemical Information
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CAS No. 2361142-23-4
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Appearance Solid
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Molecular Weight 821.81
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Formula C44H42Cl2N6O4S
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Color White to off-white
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SMILES
O=C(CCl)N(C1=CC=C(C=C1)OC2=CC=C(C=C2)OCCCCNC(C[C@H]3C4=NN=C(N4C5=C(C(C6=CC=C(C=C6)Cl)=N3)C(C)=C(S5)C)C)=O)CC7=CC=CC=C7
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Solvent & Solubility
DMSO : 100 mg/mL (121.68 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (268 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
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| DMSO | 1 mM | 1.2168 mL | 6.0841 mL | 12.1683 mL | 30.4207 mL |
| 5 mM | 0.2434 mL | 1.2168 mL | 2.4337 mL | 6.0841 mL | |
| 10 mM | 0.1217 mL | 0.6084 mL | 1.2168 mL | 3.0421 mL | |
| 15 mM | 0.0811 mL | 0.4056 mL | 0.8112 mL | 2.0280 mL | |
| 20 mM | 0.0608 mL | 0.3042 mL | 0.6084 mL | 1.5210 mL | |
| 25 mM | 0.0487 mL | 0.2434 mL | 0.4867 mL | 1.2168 mL | |
| 30 mM | 0.0406 mL | 0.2028 mL | 0.4056 mL | 1.0140 mL | |
| 40 mM | 0.0304 mL | 0.1521 mL | 0.3042 mL | 0.7605 mL | |
| 50 mM | 0.0243 mL | 0.1217 mL | 0.2434 mL | 0.6084 mL | |
| 60 mM | 0.0203 mL | 0.1014 mL | 0.2028 mL | 0.5070 mL | |
| 80 mM | 0.0152 mL | 0.0761 mL | 0.1521 mL | 0.3803 mL | |
| 100 mM | 0.0122 mL | 0.0608 mL | 0.1217 mL | 0.3042 mL |
CCW 28-3 Related Classifications
HY-156774 Related Classifications
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