Complete Freund's adjuvant (CFA, 1 mg/ml)

Name: Complete Freund's adjuvant (CFA, 1 mg/ml)
Brand: MedChemExpress
SKU: HY-153808B
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製品番号: HY-153808B: Data Sheet SDS COA 取扱説明書
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Complete Freund's adjuvant (CFA, 1 mg/ml) is an immunoadjuvant emulsified with antigen that can enhance an animal's immune response to an antigen. Complete Freund's adjuvant (CFA, 1 mg/ml) is also an inducer of the Th1 immune response and a ligand of TLRs. Complete Freund's adjuvant (CFA, 1 mg/ml) contains heat-killed inactive tuberculosis bacilli and consists of a paraffin oil-in-water emulsion. Complete Freund's adjuvant (CFA, 1 mg/ml) stimulates a strong and durable immune response and can be used to induce rheumatoid arthritis in rats, and more.

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Complete Freund's adjuvant (CFA, 1 mg/ml) 構造式

CAS 番号 : 9007-81-2

容量	価格（税別）	在庫状況	数量
Solvent
10 mL	USD 125	在庫あり	Estimated Time of Arrival: December 31
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100 mL		お問い合わせ

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カスタマーレビュー

Based on 0 publication(s) in Google Scholar

Other Forms of Complete Freund's adjuvant (CFA, 1 mg/ml):

Complete Freund's adjuvant (CFA) 在庫あり
Incomplete Freund's adjuvant (IFA) 在庫あり

Toll-like Receptor (TLR) アイソフォーム固有の製品をすべて表示:

すべてのアイソフォームを表示

TLR3 TLR8 TLR9 TLR2 TLR4 TLR7 TLR1 TLR6

生物活性
純度とドキュメンテーション
参考文献
カスタマーレビュー

製品説明

体内実験

Note:
Please do not refer to only one article to determine the experimental conditions. It is recommended to determine the optimal experimental conditions (animal strain, age, dosage, frequency and cycle, detection time and indicators, etc.) through preliminary experiments before the formal experiment.

Complete Freund's adjuvant (1 mg/ml, 0.1 mL; s.c.; once a day for two days) can be used to induce rheumatoid arthritis in Sprague-Dawley rats^[3].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model:	Sprague-Dawley rats^[3]
Dosage:	1 mg/ml, 0.1 mL
Administration:	s.c.; once a day for two days
Result:	Increased the index of thymus and spleen. Decreased the activities of GSH, CAT, SOD and MPO. Increased the level of IL-1β, IL-6, IL-17, MCP-1, TNF-α, COX-2, 5-LOX, NF-p65, IgG1 and IgG2a. Reduced level of IL-10.

CAS 番号

9007-81-2

Appearance

Liquid

Color

Colorless to light yellow

SMILES

[Complete Freund's adjuvant (CFA, 1 mg/ml)]

輸送条件

Room temperature in continental US; may vary elsewhere.

保管条件

Store at 4°C, do not freeze

純度とドキュメンテーション

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データシート (267 KB) SDS (251 KB)

COA (240 KB)

取扱説明書 (2659 KB)

参考文献

[1]. Fontes JA, et al. Complete Freund's adjuvant induces experimental autoimmune myocarditis by enhancing IL-6 production during initiation of the immune response. Immun Inflamm Dis. 2017 Jun;5(2):163-176. [Content Brief]

[2]. Ji YW, et al. Plasticity in ventral pallidal cholinergic neuron-derived circuits contributes to comorbid chronic pain-like and depression-like behaviour in male mice. Nat Commun. 2023 Apr 17;14(1):2182. [Content Brief]

[3]. Weng W, et al. Protective effect of Corynoline on the CFA induced Rheumatoid arthritis via attenuation of oxidative and inflammatory mediators. Mol Cell Biochem. 2021 Feb;476(2):831-839. [Content Brief]