1. Membrane Transporter/Ion Channel Neuronal Signaling
  2. nAChR
  3. Dipeptide diaminobutyroyl benzylamide diacetate

Dipeptide diaminobutyroyl benzylamide diacetate 

Cat. No.: HY-P0102 Pureté: 99.72%
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Dipeptide diaminobutyroyl benzylamide diacetate, a Wagerlin-1-mimicking peptide, is a nAChR antagonist. Dipeptide diaminobutyroyl benzylamide diacetate mimics Waglerin-1 to block neuromuscular junction nicotinic acetylcholine receptors, partially inhibits neuronal signal transduction, and relaxes muscles. Dipeptide diaminobutyroyl benzylamide diacetate reduces appearance of facial wrinkles linked to repeated muscle movement.Dipeptide diaminobutyroyl benzylamide diacetate can be used for the research of mild-to-moderate fine and coarse periocular and perioral wrinkles and periorbital ageing.

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Synthèse de peptides personnalisée

Dipeptide diaminobutyroyl benzylamide diacetate

Dipeptide diaminobutyroyl benzylamide diacetate Chemical Structure

CAS No. : 823202-99-9

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Description

Dipeptide diaminobutyroyl benzylamide diacetate, a Wagerlin-1-mimicking peptide, is a nAChR antagonist. Dipeptide diaminobutyroyl benzylamide diacetate mimics Waglerin-1 to block neuromuscular junction nicotinic acetylcholine receptors, partially inhibits neuronal signal transduction, and relaxes muscles. Dipeptide diaminobutyroyl benzylamide diacetate reduces appearance of facial wrinkles linked to repeated muscle movement.Dipeptide diaminobutyroyl benzylamide diacetate can be used for the research of mild-to-moderate fine and coarse periocular and perioral wrinkles and periorbital ageing[1][2].

In Vitro

Dipeptide diaminobutyroyl benzylamide diacetate is an anti-wrinkle polypeptide that can be used in cosmetic research[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Masse moléculaire

495.57

Formule

C23H37N5O7

CAS No.
Appearance

Solid

Color

White to off-white

Sequence

{beta-Ala}-Pro-{Dab-NHBzl}

Sequence Shortening

{beta-Ala}-P-{Dab-NHBzl}

Livraison

Room temperature in continental US; may vary elsewhere.

Stockage

Sealed storage, away from moisture

Powder -80°C 2 years
-20°C 1 year

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

Solvant et solubilité
In Vitro: 

DMSO : 100 mg/mL (201.79 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.0179 mL 10.0894 mL 20.1788 mL
5 mM 0.4036 mL 2.0179 mL 4.0358 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

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Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

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Calculation results:
Working solution concentration: mg/mL
Pureté et documentation

Purity: 99.72%

Références

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 2.0179 mL 10.0894 mL 20.1788 mL 50.4470 mL
5 mM 0.4036 mL 2.0179 mL 4.0358 mL 10.0894 mL
10 mM 0.2018 mL 1.0089 mL 2.0179 mL 5.0447 mL
15 mM 0.1345 mL 0.6726 mL 1.3453 mL 3.3631 mL
20 mM 0.1009 mL 0.5045 mL 1.0089 mL 2.5223 mL
25 mM 0.0807 mL 0.4036 mL 0.8072 mL 2.0179 mL
30 mM 0.0673 mL 0.3363 mL 0.6726 mL 1.6816 mL
40 mM 0.0504 mL 0.2522 mL 0.5045 mL 1.2612 mL
50 mM 0.0404 mL 0.2018 mL 0.4036 mL 1.0089 mL
60 mM 0.0336 mL 0.1682 mL 0.3363 mL 0.8408 mL
80 mM 0.0252 mL 0.1261 mL 0.2522 mL 0.6306 mL
100 mM 0.0202 mL 0.1009 mL 0.2018 mL 0.5045 mL
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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Nom du produit:
Dipeptide diaminobutyroyl benzylamide diacetate
Cat. No.:
HY-P0102
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