2. Metabolic Enzyme/Protease
  3. Factor Xa
  4. Edoxaban M4

Edoxaban M4 (D21-2393) is an orally active and selective Factor Xa inhibitor with a human Factor Xa IC50 of 1.8 nM. Edoxaban M4 exhibits anticoagulant activity via Factor Xa inhibition. Edoxaban M4 can be used for the research of non-valvular atrial fibrillation, venous thromboembolisms, pulmonary embolism.

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Edoxaban M4

Edoxaban M4 Estructura química

No. CAS : 834919-19-6

Tamaño Precio Stock Cantidad
Solid + Solvent (Highly Recommended)
10 mM * 1 mL in DMSO
ready for reconstitution
 En stock
Solution
10 mM * 1 mL in DMSO En stock
Solid
5 mg En stock
10 mg En stock
25 mg En stock
50 mg   Obtener un presupuesto  
100 mg   Obtener un presupuesto  

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Edoxaban M4 Related Antibodies

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Descripciòn

Edoxaban M4 (D21-2393) is an orally active and selective Factor Xa inhibitor with a human Factor Xa IC50 of 1.8 nM. Edoxaban M4 exhibits anticoagulant activity via Factor Xa inhibition. Edoxaban M4 can be used for the research of non-valvular atrial fibrillation, venous thromboembolisms, pulmonary embolism[1][2].

In Vitro

Edoxaban M4 inhibits human factor Xa with an IC50 of 1.8 nM[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Edoxaban M4 Related Antibodies
Peso molecular

520.99

Fòrmula

C22H25ClN6O5S
No. CAS
Appearance

Solid

Color

White to off-white

SMILES

O=C(O)[C@@H]1C[C@H]([C@H](CC1)NC(C(NC2=NC=C(C=C2)Cl)=O)=O)NC(C3=NC4=C(CN(CC4)C)S3)=O
Envío

Room temperature in continental US; may vary elsewhere.
Almacenamiento
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Solvente y solubilidad
In Vitro: 

DMSO : 25 mg/mL (47.99 mM; ultrasonic and warming and heat to 60°C; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 1.9194 mL 9.5971 mL 19.1942 mL
5 mM 0.3839 mL 1.9194 mL 3.8388 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

  • Calculadora de molaridad

  • Calculadora de dilución

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

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g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Pureza y Documentación

Purity: 98.83%

SDS (394 KB)

COA (256 KB) HNMR (305 KB) LCMS (103 KB)

Instrucciones de manejo (2659 KB)
Referencias

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 1.9194 mL 9.5971 mL 19.1942 mL 47.9856 mL
5 mM 0.3839 mL 1.9194 mL 3.8388 mL 9.5971 mL
10 mM 0.1919 mL 0.9597 mL 1.9194 mL 4.7986 mL
15 mM 0.1280 mL 0.6398 mL 1.2796 mL 3.1990 mL
20 mM 0.0960 mL 0.4799 mL 0.9597 mL 2.3993 mL
25 mM 0.0768 mL 0.3839 mL 0.7678 mL 1.9194 mL
30 mM 0.0640 mL 0.3199 mL 0.6398 mL 1.5995 mL
40 mM 0.0480 mL 0.2399 mL 0.4799 mL 1.1996 mL
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Edoxaban M4 Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Edoxaban M4834919-19-6D21-2393Edoxaban M 4Edoxaban M-4Factor XaFxanon-valvular atrial fibrillationrifampicincarbamazepinechromogenic anti-Xa assaysvenous thromboembolismshuman Factor Xapulmonary embolismanticoagulant activityhuman pooled plasmaInhibitorinhibitorinhibit

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Inquiry Information

Nombre del producto:
Edoxaban M4
Cat. No.:
HY-119124
Cantidad:
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SAFETY DATA SHEET (SDS)

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