2. Vitamin D Related/Nuclear Receptor
  3. Estrogen Receptor/ERR
  4. Enclomiphene hydrochloride

Enclomiphene hydrochloride  (Synonyms: (E)-Clomiphene hydrochloride; trans-Clomiphene hydrochloride; Enclomifene hydrochloride)

Cat. No.: HY-118861B
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Enclomiphene ((E)-Clomiphene) hydrochloride is a potent and orally active non-steroidal estrogen receptor antagonist, with antioestrogenic property. Enclomiphene hydrochloride can be used for the research of ovarian dysfunction, testosterone deficiency, male hypogonadism and type 2 diabetes.

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Enclomiphene hydrochloride

Enclomiphene hydrochloride Estructura química

No. CAS : 14158-65-7

Tamaño Precio Stock Cantidad
1 mg Obtener un presupuesto 3 - 4 Weeks 4 - 5 Weeks 5 - 6 Weeks 2 - 3 weeks
5 mg Obtener un presupuesto 3 - 4 Weeks 4 - 5 Weeks 5 - 6 Weeks 2 - 3 weeks
10 mg Obtener un presupuesto 3 - 4 Weeks 4 - 5 Weeks 5 - 6 Weeks 2 - 3 weeks
50 mg   Obtener un presupuesto  
100 mg   Obtener un presupuesto  
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Enclomiphene hydrochloride Related Antibodies

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1 Publications Citing Use of MCE Enclomiphene hydrochloride

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Estrogen receptor ERα ERβ ERRα ERRβ ERRγ

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Descripciòn

Enclomiphene ((E)-Clomiphene) hydrochloride is a potent and orally active non-steroidal estrogen receptor antagonist, with antioestrogenic property. Enclomiphene hydrochloride can be used for the research of ovarian dysfunction, testosterone deficiency, male hypogonadism and type 2 diabetes[1].

In Vitro

Enclomiphene hydrochloride (0-100 μM, 6 h) dose-dependently inhibits basal and gonadotrophin-stimulated small and large ovine luteal cell progesterone secretion[2].
Enclomiphene hydrochloride (0-100 μg/mL, 24 h) dose-dependently inhibits fertilization rates, blastocyst formation rates, and degeneration rates in mouse oocytes[3].
Enclomiphene hydrochloride (1 nM-10 μM, 6 h) dose-dependently decreases E2-induced inhibition of follicle stimulating hormone (FSH) secretion in primary sheep pituitary cells[4].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Enclomiphene hydrochloride Related Antibodies
In Vivo

Enclomiphene hydrochloride (subcutaneous injection, 0.25 and 0.5 mg/animal, daily) inhibits spermatogenesis and decreases serum luteinizing hormone (LH) and testosterone levels in intact or castrated rats[5].
Enclomiphene hydrochloride (oral adminstration, 0.03-3 mg/kg, daily for 90 days) reductes body weight to sham levels, and reduced serum cholesterol[6].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model: 21 days-old Charles River male rats[5]
Dosage: 0.25 and 0.5 mg/animal, daily for 24 days.
Administration: Subcutaneous injection
Result: Decreased LH and testosterone levels in the serum.
Animal Model: OVX (ovariectomy) rat model[6]
Dosage: 0.03, 1, and 3 mg/kg, daily for 90 days.
Administration: Oral adminstration
Result: Reducted body weight to sham levels, and reduced serum cholesterol.
Showed dose-dependent effects on the proximal tibia with BMD and BMC approaching posttreatment Sham levels.
Peso molecular

442.42

Fòrmula

C26H29Cl2NO
No. CAS
SMILES

Cl/C(C1=CC=CC=C1)=C(C2=CC=CC=C2)/C3=CC=C(C=C3)OCCN(CC)CC.Cl
Envío

Room temperature in continental US; may vary elsewhere.
Almacenamiento

Please store the product under the recommended conditions in the Certificate of Analysis.
Pureza y Documentación
Referencias
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Enclomiphene hydrochloride Related Classifications

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The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass   Concentration   Volume   Molecular Weight *
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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Enclomiphene14158-65-7(E)-Clomiphenetrans-ClomipheneEnclomifeneEstrogen Receptor/ERRHypogonadalhypogonadismtestosterone deficiencyovarian dysfunctionhormoneenclomiphene citrateestrogen receptor modulatortestosteroneInhibitorinhibitorinhibit

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Nombre del producto:
Enclomiphene hydrochloride
Cat. No.:
HY-118861B
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