Ep vinyl quinidine  (Synonyms: 3-Epiquinine; Epivinylquinidine)

Ep vinyl quinidine (3-Epiquinine) is an epi-vinyl stereoisomer of Quinidine. Quinidine is an antiarrhythmic agent. Quinidine is a potent, orally active, selective cytochrome P450db inhibitor. Quinidine is also a K+ channel blocker with an IC₅₀ of 19.9 μM. Quinidine can be used for malaria research^[1][2][3].

Parasite^[1]

324.42

C₂₀H₂₄N₂O₂

101143-87-7

O[C@H]([C@]1([H])[N@@]2C[C@H]([C@@H](CC2)C1)C=C)C3=CC=NC4=C3C=C(OC)C=C4

Room temperature in continental US; may vary elsewhere.

Please store the product under the recommended conditions in the Certificate of Analysis.

• [1]. Hu B, et al. Origin of and a Solution for Uneven Efficiency by Cinchona Alkaloid-Derived, Pseudoenantiomeric Catalysts for Asymmetric Reactions. J Am Chem Soc. 2018 Oct 24;140(42):13913-13920.  [Content Brief]

  [2]. Kehl SJ. Quinidine-induced inhibition of the fast transient outward K+ current in rat melanotrophs. Br J Pharmacol. 1991 Jul;103(3):1807-13.  [Content Brief]

  [3]. Roden DM, et al. Class I antiarrhythmic agents: quinidine, procainamide and N-acetylprocainamide, disopyramide. Pharmacol Ther. 1983;23(2):179-91.  [Content Brief]