1. Membrane Transporter/Ion Channel
  2. Potassium Channel
  3. HMR 1556

HMR 1556 

Cat. No.: HY-106369 Purity: >99.0%
Handling Instructions

HMR 1556, a chromanol derivative, is a IKs blocker with IC50s of 10.5 nM and 34 nM in canine and guinea pig left ventricular myocytes, respectively.

For research use only. We do not sell to patients.

HMR 1556 Chemical Structure

HMR 1556 Chemical Structure

CAS No. : 223749-46-0

Size Price Stock Quantity
10 mM * 1 mL in DMSO USD 176 In-stock
Estimated Time of Arrival: December 31
5 mg USD 160 In-stock
Estimated Time of Arrival: December 31
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Based on 1 publication(s) in Google Scholar

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Description

HMR 1556, a chromanol derivative, is a IKs blocker with IC50s of 10.5 nM and 34 nM in canine and guinea pig left ventricular myocytes, respectively[1][2].

IC50 & Target

IC50: 10.5 nM (IKs in canine left ventricular myocytes), 34 nM (IKs in guinea pig left ventricular myocytes)[1]

In Vitro

HMR 1556 inhibits Ito, ICa,L and IKr with IC50s of 33.9 μM, 27.5 μM, 12.6 μM in canine left ventricular myocytes, respectively[1].

Molecular Weight

411.44

Formula

C₁₇H₂₄F₃NO₅S

CAS No.

223749-46-0

SMILES

CS(N([[email protected]]1C2=CC(OCCCC(F)(F)F)=CC=C2OC(C)(C)[[email protected]@H]1O)C)(=O)=O

Shipping

Room temperature in continental US; may vary elsewhere

Storage
Powder -20°C 3 years
  4°C 2 years
In solvent -80°C 6 months
  -20°C 1 month
References

Purity: >99.0%

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HMR 1556
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