1. Membrane Transporter/Ion Channel
  2. Potassium Channel
  3. HMR 1556

HMR 1556 

Cat. No.: HY-106369
Handling Instructions

HMR 1556, a chromanol derivative, is a IKs blocker with IC50s of 10.5 nM and 34 nM in canine and guinea pig left ventricular myocytes, respectively.

For research use only. We do not sell to patients.

HMR 1556 Chemical Structure

HMR 1556 Chemical Structure

CAS No. : 223749-46-0

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Description

HMR 1556, a chromanol derivative, is a IKs blocker with IC50s of 10.5 nM and 34 nM in canine and guinea pig left ventricular myocytes, respectively[1][2].

IC50 & Target

IC50: 10.5 nM (IKs in canine left ventricular myocytes), 34 nM (IKs in guinea pig left ventricular myocytes)[1]

In Vitro

HMR 1556 inhibits Ito, ICa,L and IKr with IC50s of 33.9 μM, 27.5 μM, 12.6 μM in canine left ventricular myocytes, respectively[1].

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

References
Molecular Weight

411.44

Formula

C₁₇H₂₄F₃NO₅S

CAS No.

223749-46-0

SMILES

CS(N([[email protected]]1C2=CC(OCCCC(F)(F)F)=CC=C2OC(C)(C)[[email protected]@H]1O)C)(=O)=O

Shipping

Room temperature in continental US; may vary elsewhere

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This equation is commonly abbreviated as: C1V1 = C2V2

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Product Name:
HMR 1556
Cat. No.:
HY-106369
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HMR 1556

Cat. No.: HY-106369