2. GPCR/G Protein Neuronal Signaling
  3. mAChR
  4. L-Hyoscyamine-d3

L-Hyoscyamine-d3  (Synonyms: Daturine-d3)

製品番号: HY-N0471S 純度: 98.87%
COA 取扱説明書 Technical Support

L-Hyoscyamine-d3 is the deuterium labeled L-Hyoscyamine. L-Hyoscyamine (Daturine), a natural plant tropane alkaloid, is a potent and competitive muscarinic receptor (MR) antagonist. L-Hyoscyamine is a levo-isomer to Atropine (HY-B1205).

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L-Hyoscyamine-d<sub>3</sub>

L-Hyoscyamine-d3 構造式

CAS 番号 : 3032205-96-9

容量 価格（税別） 在庫状況 数量
1 mg $650 在庫あり
5 mg   お問い合わせ  
10 mg   お問い合わせ  

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L-Hyoscyamine-d3 関連抗体

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製品説明

L-Hyoscyamine-d3 is the deuterium labeled L-Hyoscyamine. L-Hyoscyamine (Daturine), a natural plant tropane alkaloid, is a potent and competitive muscarinic receptor (MR) antagonist. L-Hyoscyamine is a levo-isomer to Atropine (HY-B1205)[1][2].

Application

1. This compound can be used as a tracer.
2. This compound can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.

体外実験

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

L-Hyoscyamine-d3 関連抗体
分子量

292.39

分子式

C17H20D3NO3
CAS 番号
Unlabeled CAS
Appearance

Solid

Color

White to off-white

SMILES

O=C([C@@H](C1=CC=CC=C1)CO)O[C@H]2C[C@H]3CC[C@H](N3C([2H])([2H])[2H])C2
輸送条件

Room temperature in continental US; may vary elsewhere.
保管条件
Powder -20°C 3 years
  4°C 2 years
In solvent -80°C 6 months
  -20°C 1 month
溶剤 & 溶解度
体外: 

DMSO : 100 mg/mL (342.01 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 3.4201 mL 17.1004 mL 34.2009 mL
5 mM 0.6840 mL 3.4201 mL 6.8402 mL
10 mM 0.3420 mL 1.7100 mL 3.4201 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
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Volume
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Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

一般には略語で表示されます：C1V1 = C2V2

濃度 （開始）

C1

×
体積 （開始）

V1

=
濃度 （終了）

C2

×
体積 （終了）

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

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Calculation results:
Working solution concentration: mg/mL
純度とドキュメンテーション
参考文献

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 3.4201 mL 17.1004 mL 34.2009 mL 85.5022 mL
5 mM 0.6840 mL 3.4201 mL 6.8402 mL 17.1004 mL
10 mM 0.3420 mL 1.7100 mL 3.4201 mL 8.5502 mL
15 mM 0.2280 mL 1.1400 mL 2.2801 mL 5.7001 mL
20 mM 0.1710 mL 0.8550 mL 1.7100 mL 4.2751 mL
25 mM 0.1368 mL 0.6840 mL 1.3680 mL 3.4201 mL
30 mM 0.1140 mL 0.5700 mL 1.1400 mL 2.8501 mL
40 mM 0.0855 mL 0.4275 mL 0.8550 mL 2.1376 mL
50 mM 0.0684 mL 0.3420 mL 0.6840 mL 1.7100 mL
60 mM 0.0570 mL 0.2850 mL 0.5700 mL 1.4250 mL
80 mM 0.0428 mL 0.2138 mL 0.4275 mL 1.0688 mL
100 mM 0.0342 mL 0.1710 mL 0.3420 mL 0.8550 mL
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L-Hyoscyamine-d3 Related Classifications

  • Molarity Calculator

  • Dilution Calculator

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

質量   濃度   体積   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

一般には略語で表示されます：C1V1 = C2V2

濃度 （開始） × 体積 （開始） = 濃度 （終了） × 体積 （終了）
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

L-Hyoscyamine-d33032205-96-9Daturine-d3mAChRMuscarinic acetylcholine receptorInhibitorinhibitorinhibit

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製品名:
L-Hyoscyamine-d3
製品番号:
HY-N0471S
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